Novotny, Brenna

TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.

Gratuze, M., Schlachetzki, J. C. M., D’Oliveira Albanus, R., Jain, N., Novotny, B., Brase, L., Rodriguez, L., Mansel, C., Kipnis, M., O’Brien, S., et al. (2023) · Neuron

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 115

Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer’s disease

Sung, Y. J., Yang, C., Norton, J., Johnson, M., Fagan, A., Bateman, R. J., Perrin, R. J., Morris, J. C., Farlow, M. R., Chhatwal, J. P., et al. (2023) · Science Translational Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 84

Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer’s disease

Eteleeb, A. M., Novotny, B. C., Tarraga, C. S., Sohn, C., Dhungel, E., Brase, L., Nallapu, A., Buss, J., Farias, F., Bergmann, K., et al. (2024) · PLOS Biology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 64

Generating dermatopathology reports from gigapixel whole slide images with HistoGPT

Tran, M., Schmidle, P., Guo, R. R., Wagner, S. J., Koch, V., Lupperger, V., Novotny, B., Murphree, D. H., Hardway, H. D., D’Amato, M., et al. (2025) · Nature Communications

AI in cancer detectionArtificial Intelligence in Healthcare and Education

Cited by 36

Systematic analysis of cellular cross-talk reveals a role for SEMA6D-TREM2 regulating microglial function in Alzheimer’s disease

D’Oliveira Albanus, R., Finan, G. M., Brase, L., Sweeney, N., Kim, T. Y., Chen, S., Ryoo, Y., Park, J., Guo, Q., Iyer, A. K., et al. (2025) · Science Translational Medicine

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 19

Genetic and glial heterogeneity in Alzheimer disease

Brase, L., You, S., Novotny, B. C., Soriano‐Tarraga, C., Morris, J. C., Bateman, R. J., Perrin, R. J., McDade, E., Goate, A., Karch, C. M., et al. (2022) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1