Gauthier, Karine

Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease

Finan, B., Clemmensen, C., Zhu, Z., Stemmer, K., Gauthier, K., Müller, L., De Angelis, M., Moreth, K., Neff, F., Perez-Tilve, D., et al. (2016) · Cell

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 191

Congenital Hypothyroid Pax8−/− Mutant Mice Can Be Rescued by Inactivating the TRα Gene

Flamant, F., Poguet, A.-L., Plateroti, M., Chassande, O., Gauthier, K., Streichenberger, N., Mansouri, A., & Samarut, J. (2002) · Molecular Endocrinology

Thyroid Disorders and TreatmentsDevelopmental Biology and Gene Regulation

Cited by 184

Thyroid hormone receptor and ERRα coordinately regulate mitochondrial fission, mitophagy, biogenesis, and function

Singh, B. K., Sinha, R. A., Tripathi, M., Mendoza, A., Ohba, K., Sy, J. A. C., Xie, S. Y., Zhou, J., Ho, J. P., Chang, C.-Y., et al. (2018) · Science Signaling

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 145

TRα Protects Against Atherosclerosis in Male Mice: Identification of a Novel Anti-Inflammatory Property for TRα in Mice

Billon, C., Canaple, L., Fleury, S., Deloire, A., Beylot, M., Dombrowicz, D., del Carmine, P., Samarut, J., & Gauthier, K. (2014) · Endocrinology

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 45

Methylcytosine dioxygenase TET3 interacts with thyroid hormone nuclear receptors and stabilizes their association to chromatin

Guan, W., Guyot, R., Samarut, J., Flamant, F., Wong, J., & Gauthier, K. C. (2017) · Proceedings of the National Academy of Sciences

Thyroid Disorders and TreatmentsEstrogen and related hormone effects

Cited by 32

Lack of muscle mTOR kinase activity causes early onset myopathy and compromises whole‐body homeostasis

Zhang, Q., Duplany, A., Moncollin, V., Mouradian, S., Goillot, E., Mazelin, L., Gauthier, K., Streichenberger, N., Angleraux, C., Chen, J., et al. (2019) · Journal of Cachexia, Sarcopenia and Muscle

Muscle Physiology and DisordersPI3K/AKT/mTOR signaling in cancer

Cited by 31

Central vs. Peripheral Action of Thyroid Hormone in Adaptive Thermogenesis: A Burning Topic

Zekri, Y., Flamant, F., & Gauthier, K. (2021) · Cells

Adipose Tissue and MetabolismThyroid Disorders and Treatments

Cited by 27

Thyroid hormone receptor regulates hepatic stellate cell activation

Manka, P. P., Coombes, J. D., Bechmann, L. P., Dollé, L., Swiderska-Syn, M., Briones-Orta, M. A., Williams, R., van Grunsven, L., Canbay, A., Flamant, F., et al. (2017) · Journal of Hepatology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 14

An extended transcription factor regulatory network controls hepatocyte identity

Dubois‐Chevalier, J., Gheeraert, C., Berthier, A., Boulet, C., Dubois, V., Guille, L., Fourcot, M., Marot, G., Gauthier, K., Dubuquoy, L., et al. (2023) · EMBO Reports

Liver physiology and pathologyGene Regulatory Network Analysis

Cited by 6