Rottner, Klemens

Regulation of actin dynamics by WASP and WAVE family proteins

Stradal, T. E. B., Rottner, K., Disanza, A., Confalonieri, S., Innocenti, M., & Scita, G. (2004) · Trends in Cell Biology

Cellular Mechanics and InteractionsProtein Kinase Regulation and GTPase Signaling

Cited by 286

Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes

Leithner, A., Eichner, A., Müller, J., Reversat, A., Brown, M., Schwarz, J., Merrin, J., de Gorter, D. J. J., Schur, F., Bayerl, J., et al. (2016) · Nature Cell Biology

Cellular Mechanics and InteractionsProtein Kinase Regulation and GTPase Signaling

Cited by 163

WAVE regulatory complex

Rottner, K., Stradal, T. E. B., & Chen, B. (2021) · Current Biology

Cellular Mechanics and InteractionsProtein Kinase Regulation and GTPase Signaling

Cited by 116

Distinct Interaction Sites of Rac GTPase with WAVE Regulatory Complex Have Non-redundant Functions in Vivo

Schaks, M., Singh, S. P., Kage, F., Thomason, P., Klünemann, T., Steffen, A., Blankenfeldt, W., Stradal, T. E., Insall, R. H., & Rottner, K. (2018) · Current Biology

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

Cited by 85

Structures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase

Ding, B., Yang, S., Schaks, M., Liu, Y., Brown, A. J., Rottner, K., Chowdhury, S., & Chen, B. (2022) · Nature Communications

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

Cited by 82

Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

Dubielecka, P. M., Ladwein, K. I., Xiong, X., Migeotte, I., Chorzalska, A., Anderson, K. V., Sawicki, J. A., Rottner, K., Stradal, T. E., & Kotula, L. (2011) · Proceedings of the National Academy of Sciences

Cellular Mechanics and InteractionsProtein Kinase Regulation and GTPase Signaling

Cited by 66

The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity

Salzer, E., Zoghi, S., Kiss, M. G., Kage, F., Rashkova, C., Stahnke, S., Haimel, M., Platzer, R., Caldera, M., Ardy, R. C., et al. (2020) · Science Immunology

T-cell and B-cell ImmunologySystemic Lupus Erythematosus Research

Cited by 48

Arf GTPase activates the WAVE regulatory complex through a distinct binding site

Yang, S., Tang, Y., Liu, Y., Brown, A. J., Schaks, M., Ding, B., Kramer, D. A., Mietkowska, M., Ding, L., Alekhina, O., et al. (2022) · Science Advances

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

Cited by 24