Schürer, Stephan C.

Proteogenomic and metabolomic characterization of human glioblastoma

Wang, L.-B., Karpova, A., Gritsenko, M. A., Kyle, J. E., Cao, S., Li, Y., Rykunov, D., Colaprico, A., Rothstein, J. H., Hong, R., et al. (2021) · Cancer Cell

Glioma Diagnosis and TreatmentCancer Genomics and Diagnostics

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Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand

Solt, L. A., Kumar, N., Nuhant, P., Wang, Y., Lauer, J. L., Liu, J., Istrate, M. A., Kamenecka, T. M., Roush, W. R., Vidović, D., et al. (2011) · Nature

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

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The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

Keenan, A. B., Jenkins, S. L., Jagodnik, K. M., Koplev, S., He, E., Torre, D., Wang, Z., Dohlman, A. B., Silverstein, M. C., Lachmann, A., et al. (2018) · Cell Systems

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

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Unexplored therapeutic opportunities in the human genome

Oprea, T. I., Bologa, C. G., Brunak, S., Campbell, A., Gan, G. N., Gaulton, A., Gomez, S. M., Guha, R., Hersey, A., Holmes, J., et al. (2018) · Nature Reviews Drug Discovery

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

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Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer

Petralia, F., Tignor, N., Reva, B., Koptyra, M., Chowdhury, S., Rykunov, D., Krek, A., Ma, W., Zhu, Y., Ji, J., et al. (2020) · Cell

Glioma Diagnosis and TreatmentCancer Genomics and Diagnostics

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Pharos: collating protein information to shed light on the druggable genome

Nguyen, D.-T., Mathias, S., Bologa, C., Brunak, S., Fernandez, N., Gaulton, A., Hersey, A., Holmes, J., Jensen, L. J., Karlsson, A., et al. (2017) · Nucleic Acids Research

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

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Data Portal for the Library of Integrated Network-based cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data

Koleti, A., Terryn, R., Stathias, V., Chung, C., Cooper, D. J., Turner, J. P., Vidović, D., Forlin, M., Kelley, T. T., D’Urso, A., et al. (2018) · Nucleic Acids Research

Bioinformatics and Genomic NetworksResearch Data Management Practices

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LINCS Data Portal 2.0: next generation access point for perturbation-response signatures

Stathias, V., Turner, J., Koleti, A., Vidovic, D., Cooper, D., Fazel-Najafabadi, M., Pilarczyk, M., Terryn, R., Chung, C., Umeano, A., et al. (2020) · Nucleic Acids Research

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

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TCRD and pharos 2021: mining the human proteome for disease biology

Sheils, T. K., Mathias, S. L., Kelleher, K. J., Siramshetty, V. B., Nguyen, D.-T., Bologa, C. G., Jensen, L. J., Vidović, D., Koleti, A., Schürer, S. C., et al. (2021) · Nucleic Acids Research

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

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Pharos 2023: an integrated resource for the understudied human proteome

Kelleher, K. J., Sheils, T. K., Mathias, S. L., Yang, J. J., Metzger, V. T., Siramshetty, V. B., Nguyen, D.-T., Jensen, L. J., Vidović, D., Schürer, S. C., et al. (2023) · Nucleic Acids Research

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

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Integrative multi-omic cancer profiling reveals DNA methylation patterns associated with therapeutic vulnerability and cell-of-origin

Liang, W.-W., Lu, R. J.-H., Jayasinghe, R. G., Foltz, S. M., Porta-Pardo, E., Geffen, Y., Wendl, M. C., Lazcano, R., Kolodziejczak, I., Song, Y., et al. (2023) · Cancer Cell

Epigenetics and DNA MethylationCancer Genomics and Diagnostics

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TIN-X: target importance and novelty explorer

Cannon, D. C., Yang, J. J., Mathias, S. L., Ursu, O., Mani, S., Waller, A., Schürer, S. C., Jensen, L. J., Sklar, L. A., Bologa, C. G., et al. (2017) · Bioinformatics

Biomedical Text Mining and OntologiesBioinformatics and Genomic Networks

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A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals

Schaniel, C., Dhanan, P., Hu, B., Xiong, Y., Raghunandan, T., Gonzalez, D. M., Dariolli, R., D'Souza, S. L., Yadaw, A. S., Hansen, J., et al. (2021) · Stem Cell Reports

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

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PRosettaC outperforms AlphaFold3 for modeling PROTAC ternary complexes

Schulz, J. M., Schürer, S. I., Reynolds, R. C., & Schürer, S. C. (2025) · Scientific Reports

Protein Degradation and InhibitorsProtein Structure and Dynamics

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Benchmarking the Builders: A Comparative Analysis of PRosettaC and AlphaFold3 for Predicting PROTAC Ternary Complexes

Schulz, J. M., Schürer, S. I., Reynolds, R. C., & Schürer, S. C. (2025) · Scientific Reports

Protein Degradation and InhibitorsProtein Structure and Dynamics

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AI-Assisted Chemical Probe Discovery for the Understudied Calcium-Calmodulin Dependent Kinase, PNCK

Essegian, D. J., Chavez, V., Khurshid, R., Merchan, J. R., & Schürer, S. C. (2022) · PLoS Computational Biology

Computational Drug Discovery MethodsSynthesis and Characterization of Heterocyclic Compounds

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AI-Assisted chemical probe discovery for the understudied Calcium-Calmodulin Dependent Kinase, PNCK

Essegian, D. J., Chavez, V., Khurshid, R., Merchan, J. R., & Schürer, S. C. (2023) · PLOS Computational Biology

Computational Drug Discovery MethodsSynthesis and Characterization of Heterocyclic Compounds

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