Temple, Brenda RS

Structural basis for the activation of PLC-γ isozymes by phosphorylation and cancer-associated mutations

Hajicek, N., Keith, N. C., Siraliev-Perez, E., Temple, B. R., Huang, W., Zhang, Q., Harden, T. K., & Sondek, J. (2019) · eLife

Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancer

Cited by 89

SmgGDS is a guanine nucleotide exchange factor that specifically activates RhoA and RhoC

Hamel, B., Monaghan-Benson, E., Rojas, R. J., Temple, B. R. S., Marston, D. J., Burridge, K., & Sondek, J. (2011) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 64

Dynamics of allosteric regulation of the phospholipase C-γ isozymes upon recruitment to membranes

Siraliev-Perez, E., Stariha, J. T., Hoffmann, R. M., Temple, B. R., Zhang, Q., Hajicek, N., Jenkins, M. L., Burke, J. E., & Sondek, J. (2022) · eLife

Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancer

Cited by 18

Coro1A and TRIM67 collaborate in netrin-dependent neuronal morphogenesis

Ho, C. T., Evans, E. B., Lukasik, K., O’Shaughnessy, E. C., Shah, A., Hsu, C.-H., Temple, B., Bear, J. E., & Gupton, S. L. (2025) · Journal of Cell Biology

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 1

Coro1A and TRIM67 collaborate in netrin-dependent neuronal morphogenesis

Ho, C. T., Evans, E. B., Lukasik, K., O’Shaughnessy, E. C., Shah, A., Hsu, C.-H., Temple, B., Bear, J. E., & Gupton, S. L. (2025) · The Journal of Cell Biology

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 1