Xian, Xunde

ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling

Chen, Y., Durakoglugil, M. S., Xian, X., & Herz, J. (2010) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 368

Genetic Restoration of Plasma ApoE Improves Cognition and Partially Restores Synaptic Defects in ApoE-Deficient Mice

Lane-Donovan, C., Wong, W. M., Durakoglugil, M. S., Wasser, C. R., Jiang, S., Xian, X., & Herz, J. (2016) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 115

Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer’s disease

Xian, X., Pohlkamp, T., Durakoglugil, M. S., Wong, C. H., Beck, J. K., Lane-Donovan, C., Plattner, F., & Herz, J. (2018) · eLife

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 98

Spontaneous atherosclerosis in aged lipoprotein lipase-deficient mice with severe hypertriglyceridemia on a normal chow diet.

Zhang, X., Qi, R., Xian, X., Yang, F., Blackstein, M., Deng, X., Fan, J., Ross, C., Karasinska, J., Hayden, M. R., et al. (2008) · Circulation Research

Lipid metabolism and disordersAtherosclerosis and Cardiovascular Diseases

Cited by 98

Loss of Reelin protects against atherosclerosis by reducing leukocyte-endothelial cell adhesion and lesion macrophage accumulation

Ding, Y., Huang, L., Xian, X., Yuhanna, I. S., Wasser, C. R., Frotscher, M., Mineo, C., Shaul, P. W., & Herz, J. (2016) · Science Signaling

Atherosclerosis and Cardiovascular DiseasesCell Adhesion Molecules Research

Cited by 72

Differential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learning

Wasser, C. R., Masiulis, I., Durakoglugil, M. S., Lane-Donovan, C., Xian, X., Beffert, U., Agarwala, A., Hammer, R. E., & Herz, J. (2014) · Science Signaling

Neuroscience and Neuropharmacology ResearchAlzheimer's disease research and treatments

Cited by 48

NHE6 depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load

Pohlkamp, T., Xian, X., Wong, C. H., Durakoglugil, M. S., Werthmann, G. C., Saido, T. C., Evers, B. M., White, C. L., Connor, J., Hammer, R. E., et al. (2021) · eLife

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 46

Lrp4 domains differentially regulate limb/brain development and synaptic plasticity

Pohlkamp, T., Durakoglugil, M., Lane-Donovan, C., Xian, X., Johnson, E. B., Hammer, R. E., & Herz, J. (2015) · PLOS ONE

Neuroscience and Neuropharmacology ResearchAlzheimer's disease research and treatments

Cited by 28