Seehofer, Daniel

Multilineage communication regulates human liver bud development from pluripotency

Camp, J. G., Sekine, K., Gerber, T., Loeffler-Wirth, H., Binder, H., Gac, M., Kanton, S., Kageyama, J., Damm, G., Seehofer, D., et al. (2017) · Nature

Pluripotent Stem Cells ResearchLiver physiology and pathology

Cited by 621

The LiMAx test: a new liver function test for predicting postoperative outcome in liver surgery

Stockmann, M., Lock, J. F., Malinowski, M., Niehues, S. M., Seehofer, D., & Neuhaus, P. (2010) · HPB

Hepatocellular Carcinoma Treatment and PrognosisOrgan Transplantation Techniques and Outcomes

Cited by 260

Cell sources for in vitro human liver cell culture models

Zeilinger, K., Freyer, N., Damm, G., Seehofer, D., & Knöspel, F. (2016) · Experimental Biology and Medicine

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 230

Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control

Brosch, M., Kattler, K., Herrmann, A., von Schönfels, W., Nordström, K., Seehofer, D., Damm, G., Becker, T., Zeissig, S., Nehring, S., et al. (2018) · Nature Communications

Epigenetics and DNA MethylationLiver physiology and pathology

Cited by 98

Diploid hepatocytes drive physiological liver renewal in adult humans

Heinke, P., Rost, F., Rode, J., Trus, P., Simonova, I., Lázár, E., Feddema, J., Welsch, T., Alkass, K., Salehpour, M., et al. (2022) · Cell Systems

Liver physiology and pathologyNeurogenesis and neuroplasticity mechanisms

Cited by 73

Function and volume recovery after partial hepatectomy: influence of preoperative liver function, residual liver volume, and obesity

Lock, J. F., Malinowski, M., Seehofer, D., Hoppe, S., Röhl, R. I., Niehues, S. M., Neuhaus, P., & Stockmann, M. (2012) · Langenbeck's Archives of Surgery

Organ Transplantation Techniques and OutcomesLiver physiology and pathology

Cited by 68

Bile canaliculi formation and biliary transport in 3D sandwich-cultured hepatocytes in dependence of the extracellular matrix composition

Deharde, D., Schneider, C., Hiller, T., Fischer, N., Kegel, V., Lübberstedt, M., Freyer, N., Hengstler, J. G., Andersson, T. B., Seehofer, D., et al. (2016) · Archives of Toxicology

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 58

Increased Level of Interleukin 6 Associates With Increased 90-Day and 1-Year Mortality in Patients With End-Stage Liver Disease

Remmler, J., Schneider, C., Treuner-Kaueroff, T., Bartels, M., Seehofer, D., Scholz, M., Berg, T., & Kaiser, T. (2018) · Clinical Gastroenterology and Hepatology

Liver Disease and TransplantationSepsis Diagnosis and Treatment

Cited by 56

Epigenetic Modifications of the Liver Tumor Cell Line HepG2 Increase Their Drug Metabolic Capacity

Ruoß, M., Damm, G., Vosough, M., Ehret, L., Grom-Baumgarten, C., Petkov, M., Naddalin, S., Ladurner, R., Seehofer, D., Nussler, A., et al. (2019) · International Journal of Molecular Sciences

Pharmacogenetics and Drug MetabolismEpigenetics and DNA Methylation

Cited by 37

Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib

Sobotta, S., Raue, A., Huang, X., Vanlier, J., Jünger, A., Bohl, S., Albrecht, U., Hahnel, M. J., Wolf, S., Mueller, N. S., et al. (2017) · Frontiers in Physiology

Cytokine Signaling Pathways and InteractionsGene Regulatory Network Analysis

Cited by 28

Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human

Kolbe, E., Aleithe, S., Rennert, C., Spormann, L., Ott, F., Meierhofer, D., Gajowski, R., Stöpel, C., Hoehme, S., Kücken, M., et al. (2019) · Cell Reports

Wnt/β-catenin signaling in development and cancerHedgehog Signaling Pathway Studies

Cited by 22

Optimization of extracellular matrix for primary human hepatocyte cultures using mixed collagen-matrigel matrices

Seidemann, L., Prinz, S., Scherbel, J.-C., Götz, C., Seehofer, D., & Damm, G. (2023) · IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

Cited by 3

Investigation and Distinction of Energy Metabolism in Proliferating Hepatocytes and Hepatocellular Carcinoma Cells

Nerusch, J., Schicht, G., Herzog, N., Küpper, J.-H., Seehofer, D., & Damm, G. (2025) · Cells

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 3