Kalna, Gabriela

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress

Schug, Z. T., Peck, B., Jones, D. T., Zhang, Q., Grosskurth, S., Alam, I. S., Goodwin, L. M., Smethurst, E., Mason, S., Blyth, K., et al. (2015) · Cancer Cell

Cancer, Lipids, and MetabolismCancer, Hypoxia, and Metabolism

Cited by 820

Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase

Frezza, C., Zheng, L., Folger, O., Rajagopalan, K. N., MacKenzie, E. D., Jerby, L., Micaroni, M., Chaneton, B., Adam, J., Hedley, A., et al. (2011) · Nature

Cancer, Hypoxia, and MetabolismHeme Oxygenase-1 and Carbon Monoxide

Cited by 503

Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis

Cardaci, S., Zheng, L., MacKay, G., van den Broek, N. J. F., MacKenzie, E. D., Nixon, C., Stevenson, D., Tumanov, S., Bulusu, V., Kamphorst, J. J., et al. (2015) · Nature Cell Biology

Cancer, Hypoxia, and MetabolismCancer and biochemical research

Cited by 286

Fumarate induces redox-dependent senescence by modifying glutathione metabolism

Zheng, L., Cardaci, S., Jerby, L., MacKenzie, E. D., Sciacovelli, M., Johnson, T. I., Gaude, E., King, A., Leach, J. D. G., Edrada-Ebel, R., et al. (2015) · Nature Communications

Cancer, Hypoxia, and MetabolismRedox biology and oxidative stress

Cited by 281

Metabolic Profiling of Hypoxic Cells Revealed a Catabolic Signature Required for Cell Survival

Frezza, C., Zheng, L., Tennant, D. A., Papkovsky, D. B., Hedley, B. A., Kalna, G., Watson, D. G., & Gottlieb, E. (2011) · PLoS ONE

Cancer, Hypoxia, and MetabolismAutophagy in Disease and Therapy

Cited by 177

Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells

Zheng, L., MacKenzie, E. D., Karim, S. A., Hedley, A., Blyth, K., Kalna, G., Watson, D. G., Szlosarek, P., Frezza, C., & Gottlieb, E. (2013) · Cancer & Metabolism

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 103

Mtss1 regulates epidermal growth factor signaling in head and neck squamous carcinoma cells

Dawson, J. C., Timpson, P., Kalna, G., & Machesky, L. M. (2012) · Oncogene

HER2/EGFR in Cancer ResearchHead and Neck Cancer Studies

Cited by 42