Kranenburg, Onno

Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy

Driehuis, E., Kolders, S., Spelier, S., Lõhmussaar, K., Willems, S. M., Devriese, L. A., de Bree, R., de Ruiter, E. J., Korving, J., Begthel, H., et al. (2019) · Cancer Discovery

Cancer Cells and MetastasisHead and Neck Cancer Studies

Cited by 408

Patient-derived organoids as a predictive biomarker for treatment response in cancer patients

Wensink, G. E., Elias, S. G., Mullenders, J., Koopman, M., Boj, S. F., Kranenburg, O. W., & Roodhart, J. M. L. (2021) · npj Precision Oncology

Cancer Cells and Metastasis3D Printing in Biomedical Research

Cited by 323

Patient-derived organoids model cervical tissue dynamics and viral oncogenesis in cervical cancer

Lõhmussaar, K., Oka, R., Espejo Valle-Inclan, J., Smits, M. H. H., Wardak, H., Korving, J., Begthel, H., Proost, N., van de Ven, M., Kranenburg, O. W., et al. (2021) · Cell Stem Cell

Cervical Cancer and HPV ResearchCancer Cells and Metastasis

Cited by 211

Practical and robust identification of molecular subtypes in colorectal cancer by immunohistochemistry

Trinh, A., Trumpi, K., De Sousa E Melo, F., Wang, X., de Jong, J. H., Fessler, E., Kuppen, P. J. K., Reimers, M. S., Swets, M., Koopman, M., et al. (2017) · Clinical Cancer Research

Colorectal Cancer Treatments and StudiesGenetic factors in colorectal cancer

Cited by 180

Characterization of p190RhoGEF, A RhoA-specific Guanine Nucleotide Exchange Factor That Interacts with Microtubules

van Horck, F. P. G., Ahmadian, M. R., Haeusler, L. C., Moolenaar, W. H., & Kranenburg, O. (2001) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 174

Molecular characterization of colorectal cancer related peritoneal metastatic disease

Lenos, K. J., Bach, S., Ferreira Moreno, L., ten Hoorn, S., Sluiter, N. R., Bootsma, S., Vieira Braga, F. A., Nijman, L. E., van den Bosch, T., Miedema, D. M., et al. (2022) · Nature Communications

Intraperitoneal and Appendiceal MalignanciesColorectal Cancer Treatments and Studies

Cited by 125

Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion

Vellinga, T. T., den Uil, S., Rinkes, I. H. B., Marvin, D., Ponsioen, B., Alvarez-Varela, A., Fatrai, S., Scheele, C., Zwijnenburg, D. A., Snippert, H., et al. (2016) · Oncogene

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 115

Wip1 confers G2 checkpoint recovery competence by counteracting p53‐dependent transcriptional repression

Lindqvist, A., de Bruijn, M., Macurek, L., Brás, A., Mensinga, A., Bruinsma, W., Voets, O., Kranenburg, O., & Medema, R. H. (2009) · The EMBO Journal

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 75

Neoadjuvant chemotherapy affects molecular classification of colorectal tumors

Trumpi, K., Ubink, I., Trinh, A., Djafarihamedani, M., Jongen, J. M., Govaert, K. M., Elias, S. G., van Hooff, S. R., Medema, J. P., Lacle, M. M., et al. (2017) · Oncogenesis

Colorectal Cancer Treatments and StudiesCancer Cells and Metastasis

Cited by 46

A novel diagnostic tool for selecting patients with mesenchymal-type colon cancer reveals intratumor subtype heterogeneity

Ubink, I., Elias, S. G., Moelans, C. B., Laclé, M. M., van Grevenstein, W. M. U., van Diest, P. J., Borel Rinkes, I. H. M., & Kranenburg, O. (2017) · JNCI: Journal of the National Cancer Institute

Colorectal Cancer Treatments and StudiesGenetic factors in colorectal cancer

Cited by 40

Fibroblast activation protein identifies consensus molecular subtype 4 in colorectal cancer and allows its detection by 68Ga-FAPI-PET imaging

Strating, E., Wassenaar, E., Verhagen, M., Rauwerdink, P., van Schelven, S., de Hingh, I., Rinkes, I. B., Boerma, D., Witkamp, A., Lacle, M., et al. (2022) · British Journal of Cancer

Peptidase Inhibition and AnalysisColorectal Cancer Treatments and Studies

Cited by 36

Consensus molecular subtype 4 (CMS4)-targeted therapy in primary colon cancer: a proof-of-concept study

Peters, N. A., Constantinides, A., Ubink, I., van Kuik, J., Bloemendal, H. J., van Dodewaard, J. M., Brink, M. A., Schwartz, T. P., Lolkema, M. P. J. K., Lacle, M. M., et al. (2022) · Frontiers in Oncology

Colorectal Cancer Treatments and StudiesColorectal Cancer Surgical Treatments

Cited by 35

Associations of non-pedunculated T1 colorectal adenocarcinoma outcome with consensus molecular subtypes, immunoscore, and microsatellite status: a multicenter case-cohort study

Haasnoot, K. J. C., Backes, Y., Moons, L. M. G., Kranenburg, O., Trinh, A., Vermeulen, L., Noë, M., Tuynman, J. B., van Lent, A. U. G., van Ginneken, R., et al. (2020) · Modern Pathology

Genetic factors in colorectal cancerColorectal Cancer Treatments and Studies

Cited by 30

KIT promotes tumor stroma formation and counteracts tumor-suppressive TGFβ signaling in colorectal cancer

Küçükköse, E., Peters, N. A., Ubink, I., van Keulen, V. A. M., Daghighian, R., Verheem, A., Laoukili, J., & Kranenburg, O. (2022) · Cell Death & Disease

TGF-β signaling in diseasesCancer Cells and Metastasis

Cited by 18