Georgiadis, Anastasios

Long-Term Effect of Gene Therapy on Leber’s Congenital Amaurosis

Bainbridge, J. W. B., Mehat, M. S., Sundaram, V., Robbie, S. J., Barker, S. E., Ripamonti, C., Georgiadis, A., Mowat, F. M., Beattie, S. G., Gardner, P. J., et al. (2015) · New England Journal of Medicine

Retinal Development and DisordersVirus-based gene therapy research

Cited by 743

Development of an optimized AAV2/5 gene therapy vector for Leber congenital amaurosis owing to defects in RPE65

Georgiadis, A., Duran, Y., Ribeiro, J., Abelleira-Hervas, L., Robbie, S. J., Sünkel-Laing, B., Fourali, S., Gonzalez-Cordero, A., Cristante, E., Michaelides, M., et al. (2016) · Gene Therapy

Retinal Development and DisordersVirus-based gene therapy research

Cited by 84

Stable RAAV-Mediated Transduction of Rod and Cone Photoreceptors in the Canine Retina

Bainbridge, J. W. B., Mistry, A., Schlichtenbrede, F. C., Smith, A., Broderick, C., De Alwis, M., Georgiadis, A., Taylor, P. M., Squires, M., Sethi, C., et al. (2003) · Gene Therapy

Retinal Development and DisordersVirus-based gene therapy research

Cited by 58

Phase 1/2 AAV5-hRKp.RPGR (botaretigene sparoparvovec) gene therapy: safety and efficacy in RPGR-associated X-linked retinitis pigmentosa

MICHAELIDES, M., BESIRLI, C. G., YANG, Y., DE GUIMARAES, T. A. C., WONG, S. C., HUCKFELDT, R. M., COMANDER, J. I., SAHEL, J.-A., SHAH, S. M., TEE, J. J. L., et al. (2024) · American Journal of Ophthalmology

Retinal Development and DisordersVirus-based gene therapy research

Cited by 55

First-in-Human gene therapy trial of AAV8-hCARp.hCNGB3 in adults and children with CNGB3-associated achromatopsia

Michaelides, M., Hirji, N., Wong, S. C., Besirli, C. G., Zaman, S., Kumaran, N., Georgiadis, A., Smith, A. J., Ripamonti, C., Gottlob, I., et al. (2023) · American Journal of Ophthalmology

Retinal Development and DisordersVirus-based gene therapy research

Cited by 54

Antioxidant and lipid supplementation improve the development of photoreceptor outer segments in pluripotent stem cell-derived retinal organoids

West, E. L., Majumder, P., Naeem, A., Fernando, M., O'Hara-Wright, M., Lanning, E., Kloc, M., Ribeiro, J., Ovando-Roche, P., Shum, I. O., et al. (2022) · Stem Cell Reports

Retinal Development and DisordersPluripotent Stem Cells Research

Cited by 53

Genetic treatment for autosomal dominant inherited retinal dystrophies: Approaches, challenges and targeted genotypes

Daich Varela, M., Georgiadis, A., & Michaelides, M. (2023) · British Journal of Ophthalmology

Retinal Development and DisordersVirus-based gene therapy research

Cited by 30