Gereben, Balázs

Paradigms of dynamic control of thyroid hormone signaling

Bianco, A. C., Dumitrescu, A., Gereben, B., Ribeiro, M. O., Fonseca, T. L., Fernandes, G. W., & Bocco, B. M. L. C. (2019) · Endocrine Reviews

Thyroid Disorders and TreatmentsEstrogen and related hormone effects

Cited by 293

The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate

Dentice, M., Bandyopadhyay, A., Gereben, B., Callebaut, I., Christoffolete, M. A., Kim, B. W., Nissim, S., Mornon, J.-P., Zavacki, A. M., Zeöld, A., et al. (2005) · Nature Cell Biology

Hedgehog Signaling Pathway StudiesUbiquitin and proteasome pathways

Cited by 227

Activation and inactivation of thyroid hormone by deiodinases: Local action with general consequences

Gereben, B., Zeöld, A., Dentice, M., Salvatore, D., & Bianco, A. C. (2008) · Cellular and Molecular Life Sciences

Thyroid Disorders and TreatmentsSelenium in Biological Systems

Cited by 207

American Thyroid Association Guide to Investigating Thyroid Hormone Economy and Action in Rodent and Cell Models: Report of the American Thyroid Association Task Force on Approaches and Strategies to Investigate Thyroid Hormone Economy and Action

Bianco, A. C., Anderson, G., Forrest, D., Galton, V. A., Gereben, B., Kim, B. W., Kopp, P. A., Liao, X. H., Obregon, M. J., Peeters, R. P., et al. (2014) · Thyroid

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 205

Lipopolysaccharide Induces Type 2 Iodothyronine Deiodinase in the Mediobasal Hypothalamus: Implications for the Nonthyroidal Illness Syndrome

Fekete, C., Gereben, B., Doleschall, M., Harney, J. W., Dora, J. M., Bianco, A. C., Sarkar, S., Liposits, Z., Rand, W., Emerson, C., et al. (2004) · Endocrinology

Thyroid Disorders and TreatmentsNeuropeptides and Animal Physiology

Cited by 179

Selective Proteolysis of Human Type 2 Deiodinase: A Novel Ubiquitin-Proteasomal Mediated Mechanism for Regulation of Hormone Activation

Gereben, B., Goncalves, C., Harney, J. W., Larsen, P. R., & Bianco, A. C. (2000) · Molecular Endocrinology

Thyroid Disorders and TreatmentsUbiquitin and proteasome pathways

Cited by 161

Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells

Freitas, B. C. G., Gereben, B., Castillo, M., Kalló, I., Zeöld, A., Egri, P., Liposits, Z., Zavacki, A. M., Maciel, R. M. B., Jo, S., et al. (2010) · Journal of Clinical Investigation

Thyroid Disorders and TreatmentsEstrogen and related hormone effects

Cited by 160

Scope and limitations of iodothyronine deiodinases in hypothyroidism

Gereben, B., McAninch, E. A., Ribeiro, M. O., & Bianco, A. C. (2015) · Nature Reviews Endocrinology

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 146

Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain

Jo, S., Fonseca, T. L., Bocco, B. M. L. C., Fernandes, G. W., McAninch, E. A., Bolin, A. P., Da Conceição, R. R., Werneck-de-Castro, J. P., Ignacio, D. L., Egri, P., et al. (2018) · Journal of Clinical Investigation

Thyroid Disorders and TreatmentsEndoplasmic Reticulum Stress and Disease

Cited by 107

Ubiquitination-induced conformational change within the deiodinase dimer is a switch regulating enzyme activity

Sagar, G. D. V., Gereben, B., Callebaut, I., Mornon, J.-P., Zeöld, A., da Silva, W. S., Luongo, C., Dentice, M., Tente, S. M., Freitas, B. C. G., et al. (2007) · Molecular and Cellular Biology

Ubiquitin and proteasome pathwaysThyroid Disorders and Treatments

Cited by 103

Human longevity is characterised by high thyroid stimulating hormone secretion without altered energy metabolism

Jansen, S. W., Akintola, A. A., Roelfsema, F., van der Spoel, E., Cobbaert, C. M., Ballieux, B. E., Egri, P., Kvarta-Papp, Z., Gereben, B., Fekete, C., et al. (2015) · Scientific Reports

Thyroid Disorders and TreatmentsGenetics, Aging, and Longevity in Model Organisms

Cited by 82

A novel pathway regulates thyroid hormone availability in rat and human hypothalamic neurosecretory neurons

Kalló, I., Mohácsik, P., Vida, B., Zeöld, A., Bardóczi, Z., Zavacki, A. M., Farkas, E., Kádár, A., Hrabovszky, E., Arrojo e Drigo, R., et al. (2012) · PLoS ONE

Thyroid Disorders and TreatmentsHypothalamic control of reproductive hormones

Cited by 52

Endotoxin-induced inflammation down-regulates L-type amino acid transporter 1 (LAT1) expression at the blood-brain barrier of male rats and mice

Wittmann, G., Mohácsik, P., Balkhi, M. Y., Gereben, B., & Lechan, R. M. (2015) · Fluids and Barriers of the CNS

Barrier Structure and Function StudiesAmino Acid Enzymes and Metabolism

Cited by 43

Axonal T3 uptake and transport can trigger thyroid hormone signaling in the brain

Salas-Lucia, F., Fekete, C., Sinkó, R., Egri, P., Rada, K., Ruska, Y., Gereben, B., & Bianco, A. C. (2023) · eLife

Thyroid Disorders and TreatmentsCellular transport and secretion

Cited by 33

Sustained Pituitary T3 Production Explains the T4-mediated TSH Feedback Mechanism

Batistuzzo, A., Salas-Lucia, F., Gereben, B., Ribeiro, M. O., & Bianco, A. C. (2023) · Endocrinology

Thyroid Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 18