American Thyroid Association Guide to Investigating Thyroid Hormone Economy and Action in Rodent and Cell Models: Report of the American Thyroid Association Task Force on Approaches and Strategies to Investigate Thyroid Hormone Economy and Action

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Livak, K. J., & Schmittgen, T. D. (2001) · Methods · doi:10.1006/meth.2001.1262 · Cited by 180,860 · see citing works

Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

PARFITT, A. M., Drezner, M. K., Glorieux, F. H., Kanis, J. А., Malluche, H. H., Meunier, P. J., Ott, S. M., & Recker, R. R. (1987) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650020617 · Cited by 5,015 · see citing works

Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays

Bustin, S. A. (2000) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0250169 · Cited by 3,844 · see citing works

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Kuro-o, M., Matsumura, Y., Aizawa, H., Kawaguchi, H., Suga, T., Utsugi, T., Ohyama, Y., Kurabayashi, M., Kaname, T., Kume, E., et al. (1997) · Nature · doi:10.1038/36285 · Cited by 3,837 · see citing works

Role of leptin in the neuroendocrine response to fasting

Ahima, R. S., Prabakaran, D., Mantzoros, C., Qu, D., Lowell, B., Maratos-Flier, E., & Flier, J. S. (1996) · Nature · doi:10.1038/382250a0 · Cited by 3,117 · see citing works

Thyroid hormone and the cardiovascular system.

Klein, I., & Ojamaa, K. (2001) · New England Journal of Medicine · doi:10.1056/nejm200102153440707 · Cited by 2,300 · see citing works

Quantification of mRNA using real-time RT-PCR

Nolan, T., Hands, R. E., & Bustin, S. A. (2006) · Nature Protocols · doi:10.1038/nprot.2006.236 · Cited by 2,247 · see citing works

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

Watanabe, M., Houten, S. M., Mataki, C., Christoffolete, M. A., Kim, B. W., Sato, H., Messaddeq, N., Harney, J. W., Ezaki, O., Kodama, T., et al. (2006) · Nature · doi:10.1038/nature04330 · Cited by 2,220 · see citing works

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

Hörlein, A., Näär, A. M., Heinzel, T., Torchia, J., Gloss, B. R., Kurokawa, R., Ryan, A. K., Kamei, Y., Söderström, M., Glass, C. K., et al. (1995) · Nature · doi:10.1038/377397a0 · Cited by 2,035 · see citing works

Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases

Bianco, A. C., Salvatore, D., Gereben, B., Berry, M. J., & Larsen, P. R. (2002) · Endocrine Reviews · doi:10.1210/edrv.23.1.0455 · Cited by 1,853 · see citing works

A transcriptional co-repressor that interacts with nuclear hormone receptors

Chen, J. D., & Evans, R. M. (1995) · Nature · doi:10.1038/377454a0 · Cited by 1,794 · see citing works

A conditional knockout resource for the genome-wide study of mouse gene function

Skarnes, W. C., Rosen, B., West, A. P., Koutsourakis, M., Bushell, W., Iyer, V., Mujica, A. O., Thomas, M., Harrow, J., Cox, T., et al. (2011) · Nature · doi:10.1038/nature10163 · Cited by 1,708 · see citing works

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

Umesono, K., Murakami, K. K., Thompson, C. C., & Evans, R. M. (1991) · Cell · doi:10.1016/0092-8674(91)90020-y · Cited by 1,688 · see citing works

Control of Stress-Dependent Cardiac Growth and Gene Expression by a MicroRNA

van Rooij, E., Sutherland, L. B., Qi, X., Richardson, J. A., Hill, J. A., & Olson, E. N. (2007) · Science · doi:10.1126/science.1139089 · Cited by 1,648 · see citing works

Quantitation of mRNA by the polymerase chain reaction.

Wang, A. M., DOYLE, M. V., & Mark, D. F. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.24.9717 · Cited by 1,638 · see citing works

A role for brown adipose tissue in diet-induced thermogenesis

Rothwell, N. J., & Stock, M. J. (1979) · Nature · doi:10.1038/281031a0 · Cited by 1,606 · see citing works

The c-erb-A gene encodes a thyroid hormone receptor

Weinberger, C., Thompson, C. C., Ong, E. S., Lebo, R. V., Gruol, D. J., & Evans, R. M. (1986) · Nature · doi:10.1038/324641a0 · Cited by 1,477 · see citing works

The c-erb-A protein is a high-affinity receptor for thyroid hormone

Sap, J., Múñoz, A., Damm, K., Goldberg, Y., Ghysdael, J., Leutz, A., Beug, H., & Vennström, B. (1986) · Nature · doi:10.1038/324635a0 · Cited by 1,314 · see citing works

Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

Wang, Y.-X., Lee, C.-H., Tiep, S., Yu, R. T., Ham, J., Kang, H., & Evans, R. M. (2003) · Cell · doi:10.1016/s0092-8674(03)00269-1 · Cited by 1,296 · see citing works

Mechanisms of thyroid hormone action

Brent, G. A. (2012) · Journal of Clinical Investigation · doi:10.1172/jci60047 · Cited by 1,244 · see citing works

The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary.Preprint

Kimura, S., Hara, Y., Pineau, T., Fernández‐Salguero, P. M., Fox, C. H., Ward, J. M., & Gonzalez, F. J. (1996) · Genes & Development · doi:10.1101/gad.10.1.60 · Cited by 1,221 · see citing works

Electrophoretic mobility shift assay (EMSA) for detecting protein–nucleic acid interactions

Hellman, L. M., & Fried, M. G. (2007) · Nature Protocols · doi:10.1038/nprot.2007.249 · Cited by 1,217 · see citing works

HINDLIMB MUSCLE FIBER POPULATIONS OF FIVE MAMMALS

Ariano, M. A., Edgerton, V. R., & Armstrong, R. B. (1973) · Journal of Histochemistry & Cytochemistry · doi:10.1177/21.1.51 · Cited by 1,118 · see citing works

Cloning and characterization of the thyroid iodide transporter

Dai, G., Levy, O., & Carrasco, N. (1996) · Nature · doi:10.1038/379458a0 · Cited by 1,109 · see citing works

Werner & Ingbar's the thyroid : a fundamental and clinical text

Werner, S. C., Ingbar, S. H., Braverman, L. E., & Utiger, R. D. (2012) · Lippincott-Raven eBooks · Cited by 1,016 · see citing works

Three myosin heavy chain isoforms in type 2 skeletal muscle fibres

Schiaffino, S., Gorza, L., Sartore, S., Saggin, L., Ausoni, S., Vianello, M., Gundersen, K., & Lømo, T. (1989) · Journal of Muscle Research and Cell Motility · doi:10.1007/bf01739810 · Cited by 960 · see citing works

Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy.

Rando, T. A., & Blau, H. M. (1994) · The Journal of Cell Biology · doi:10.1083/jcb.125.6.1275 · Cited by 944 · see citing works

Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells

Wu, M., Neilson, A., Swift, A. L., Moran, R., Tamagnine, J., Parslow, D., Armistead, S., Lemire, K., Orrell, J., Teich, J., et al. (2006) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00247.2006 · Cited by 922 · see citing works

Cellular and Molecular Basis of Deiodinase-Regulated Thyroid Hormone Signaling1

Gereben, B., Zavacki, A. M., Ribich, S., Kim, B. W., Huang, S. A., Simonides, W. S., Zeöld, A., & Bianco, A. C. (2008) · Endocrine Reviews · doi:10.1210/er.2008-0019 · Cited by 891 · see citing works

The Sodium/Iodide Symporter (NIS): Characterization, Regulation, and Medical Significance

Dohán, O., la Vieja, A. D., Paroder, V., Riedel, C. A., Artani, M., Reed, M. D., Ginter, C. S., & Carrasco, N. (2003) · Endocrine Reviews · doi:10.1210/er.2001-0029 · Cited by 861 · see citing works

Laser-capture microdissection

Espina, V. A., Wulfkuhle, J. D., Calvert, V. S., VanMeter, A., Zhou, W., Coukos, G., Geho, D. H., Petricoin, E. F., & Liotta, L. A. (2006) · Nature Protocols · doi:10.1038/nprot.2006.85 · Cited by 847 · see citing works

Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily

Mackenzie, P. I., Walter Bock, K., Burchell, B., Guillemette, C., Ikushiro, S.-I., Iyanagi, T., Miners, J. O., Owens, I. S., & Nebert, D. W. (2005) · Pharmacogenetics and Genomics · doi:10.1097/01.fpc.0000173483.13689.56 · Cited by 821 · see citing works

A guide to analysis of mouse energy metabolism

Tschöp, M. H., Speakman, J. R., Arch, J. R. S., Auwerx, J., Brüning, J. C., Chan, L., Eckel, R. H., Farese, R. V., Galgani, J. E., Hambly, C., et al. (2012) · Nature Methods · doi:10.1038/nmeth.1806 · Cited by 813 · see citing works

Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment

Rogers, D. C., Fisher, E. M. C., Brown, S. D. M., Peters, J., Hunter, A. J., & Martin, J. E. (1997) · Mammalian Genome · doi:10.1007/s003359900551 · Cited by 795 · see citing works

βAR Signaling Required for Diet-Induced Thermogenesis and Obesity Resistance

Bachman, E. S., Dhillon, H., Zhang, C.-Y., Cinti, S., Bianco, A. C., Kobilka, B. K., & Lowell, B. B. (2002) · Science · doi:10.1126/science.1073160 · Cited by 782 · see citing works

Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter

Friesema, E. C. H., Ganguly, S., Abdalla, A., Fox, J. E. M., Halestrap, A. P., & Visser, T. J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300909200 · Cited by 725 · see citing works

Thyroid Hormone Action in the Heart

Kahaly, G. J., & DILLMANN, W. H. (2005) · Endocrine Reviews · doi:10.1210/er.2003-0033 · Cited by 710 · see citing works

Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation

Friesema, E. C., Grueters, A., Biebermann, H., Krude, H., von Moers, A., Reeser, M., Barrett, T. G., Mancilla, E. E., Svensson, J., Kester, M. H., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17226-7 · Cited by 709 · see citing works

A Novel Syndrome Combining Thyroid and Neurological Abnormalities Is Associated with Mutations in a Monocarboxylate Transporter Gene

Dumitrescu, A. M., Liao, X.-H., Best, T. B., Brockmann, K., & Refetoff, S. (2004) · The American Journal of Human Genetics · doi:10.1086/380999 · Cited by 706 · see citing works

Thermogenic Mechanisms and Their Hormonal Regulation

Silva, J. E. (2006) · Physiological Reviews · doi:10.1152/physrev.00009.2005 · Cited by 687 · see citing works

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

López, M., Varela, L., Vazquez, M. J., Rodríguez‐Cuenca, S., González, C. R., Velagapudi, V., Morgan, D. A., Schoenmakers, E., Agassandian, K., Lage, R., et al. (2010) · Nature Medicine · doi:10.1038/nm.2207 · Cited by 682 · see citing works

Nonshivering thermogenesis and its adequate measurement in metabolic studies

Cannon, B., & Nedergaard, J. (2011) · Journal of Experimental Biology · doi:10.1242/jeb.050989 · Cited by 677 · see citing works

Regulation of oligodendrocyte differentiation and myelination

Emery, B. (2010) · Science · doi:10.1126/science.1190927 · Cited by 653 · see citing works

Depletion of L-3,5,3'-Triiodothyronine and L-Thyroxine in Euthyroid Calf Serum for Use in Cell Culture Studies of the Action of Thyroid Hormone*

Samuels, H. H., Stanley, F. M., & Casanova, J. (1979) · Endocrinology · doi:10.1210/endo-105-1-80 · Cited by 649 · see citing works

Mammalian Skeletal Muscle Fiber Type Transitions

Pette, D., & Staron, R. S. (1997) · International review of cytology · doi:10.1016/s0074-7696(08)61622-8 · Cited by 633 · see citing works

All Members of the MHC Multigene Family Respond to Thyroid Hormone in a Highly Tissue-Specific Manner

Izumo, S., Nadal-Ginard, B., & Mahdavi, V. (1986) · Science · doi:10.1126/science.3945800 · Cited by 621 · see citing works

Follicular cells of the thyroid gland require Pax8 gene function

Mansouri, A., Chowdhury, K., & Gruß, P. (1998) · Nature Genetics · doi:10.1038/ng0598-87 · Cited by 620 · see citing works

Rapid Determination of Myosin Heavy Chain Expression in Rat, Mouse, and Human Skeletal Muscle Using Multicolor Immunofluorescence Analysis

Bloemberg, D., & Quadrilatero, J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0035273 · Cited by 613 · see citing works

Timing of thyroid hormone action in the developing brain: clinical observations and experimental findings

Zoeller, R. T., & Rovet, J. (2004) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2004.01243.x · Cited by 605 · see citing works

Scaling of energetic cost of running to body size in mammals

Taylor, C., Schmidt‐Nielsen, K., & Raab, J. (1970) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1970.219.4.1104 · Cited by 600 · see citing works

Next-generation genomics: an integrative approach

Hawkins, R. D., Hon, G. C., & Ren, B. (2010) · Nature Reviews Genetics · doi:10.1038/nrg2795 · Cited by 591 · see citing works

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex.

Fondell, J. D., Ge, H., & Roeder, R. G. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.16.8329 · Cited by 578 · see citing works

A thyroid hormone receptor that is required for the development of green cone photoreceptors

Ng, L., Hurley, J. B., Dierks, B. D., Srinivas, M., Saltó, C., Vennström, B., Reh, T. A., & Forrest, D. (2001) · Nature Genetics · doi:10.1038/83829 · Cited by 561 · see citing works

Hypophysectomy and a replacement therapy in the rat

Smith, P. E. (1930) · American Journal of Anatomy · doi:10.1002/aja.1000450203 · Cited by 554 · see citing works

Neurodevelopmental and Neurophysiological Actions of Thyroid Hormone

Williams, G. R. (2008) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2008.01733.x · Cited by 551 · see citing works

Radioimmunoassay of cyclic AMP and cyclic GMP.

Brooker, G., Jf, H., Terasaki, W. L., & Moylan, R. D. (1979) · PubMed · Cited by 549 · see citing works

Relationships between Circulating and Intracellular Thyroid Hormones: Physiological and Clinical Implications*

Larsen, P. R., Silva, J. E., & Kaplan, M. M. (1981) · Endocrine Reviews · doi:10.1210/edrv-2-1-87 · Cited by 546 · see citing works

The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue

de Jesus, L. A., Carvalho, S. D., Ribeiro, M. O., Schneider, M. J., Kim, S.-W., Harney, J. W., Larsen, P. R., & Bianco, A. C. (2001) · Journal of Clinical Investigation · doi:10.1172/jci200113803 · Cited by 537 · see citing works

Abnormal heart rate and body temperature in mice lacking thyroid hormone receptor α1

Wikström, L., Johansson, C., Saltó, C., Barlow, C., Campos‐Barros, Á., Baas, F., Forrest, D., Thorén, P., & Vennström, B. (1998) · The EMBO Journal · doi:10.1093/emboj/17.2.455 · Cited by 513 · see citing works

Quantitative assessment of myocardial collagen with picrosirius red staining and circularly polarized light

Whittaker, P., Kloner, R. A., Boughner, D. R., & Pickering, J. G. (1994) · Basic Research in Cardiology · doi:10.1007/bf00788278 · Cited by 496 · see citing works

Early maternal hypothyroxinemia alters histogenesis and cerebral cortex cytoarchitecture of the progeny

Lavado-Autric, R., Ausó, E., García‐Velasco, J., Arufe, M. C., del Rey, F. E., Berbel, P. J., & de Escobar, G. M. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200316262 · Cited by 473 · see citing works

Tissue Differences in the Concentration of Triiodothyronine Nuclear Binding Sites in the Rat: Liver, Kidney, Pituitary, Heart, Brain, Spleen and Testis

Oppenheimer, J. H., Schwartz, H. L., & Surks, M. I. (1974) · Endocrinology · doi:10.1210/endo-95-3-897 · Cited by 468 · see citing works

Advances in measuring cellular bioenergetics using extracellular flux

Ferrick, D. A., Neilson, A., & Beeson, C. C. (2008) · Drug Discovery Today · doi:10.1016/j.drudis.2007.12.008 · Cited by 455 · see citing works

Reduced Activation and Increased Inactivation of Thyroid Hormone in Tissues of Critically Ill Patients

Peeters, R. P., Wouters, P. J., Kaptein, E., van Toor, H., Visser, T. J., & Van den Berghe, G. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-022013 · Cited by 452 · see citing works

Thyroid hormone metabolism

HENNEMANN, G. (1986) · M. Dekker eBooks · Cited by 451 · see citing works

Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitary-thyroid axis, growth, and bone maturationPreprint

Gothe, S., Wang, Z., Ng, L., Kindblom, J. M., Campos‐Barros, Á., Ohlsson, C., Vennström, B., & Forrest, D. (1999) · Genes & Development · doi:10.1101/gad.13.10.1329 · Cited by 445 · see citing works

Recessive resistance to thyroid hormone in mice lacking thyroid hormone receptor beta: evidence for tissue‐specific modulation of receptor function.

Forrest, D., Hanebuth, E., Smeyne, R. J., Everds, N. E., Stewart, C. L., Wehner, J. M., & Curran, T. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00664.x · Cited by 440 · see citing works

Different functions for the thyroid hormone receptors TRα and TRβ in the control of thyroid hormone production and post‐natal development

Gauthier, K. C., Chassande, O., Plateroti, M., Roux, J., Legrand, C., Pain, B., Rousset, B., Weiss, R. E., Trouillas, J., & Samarut, J. (1999) · The EMBO Journal · doi:10.1093/emboj/18.3.623 · Cited by 414 · see citing works

Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family

Hagenbuch, B., & Gui, C. (2008) · Xenobiotica · doi:10.1080/00498250801986951 · Cited by 410 · see citing works

Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation

Chakravarty, D., Santos, E. B., Ryder, M. M., Knauf, J. A., Liao, X.-H., West, B. L., Bollag, G. E., Kolesnick, R. N., Thin, T. H., Rosen, N. X., et al. (2011) · Journal of Clinical Investigation · doi:10.1172/jci46382 · Cited by 391 · see citing works

Minireview: Thyroid Hormone Transporters: The Knowns and the Unknowns

Visser, W. E., Friesema, E. C. H., & Visser, T. J. (2011) · Molecular Endocrinology · doi:10.1210/me.2010-0095 · Cited by 390 · see citing works

Firefly luciferase as a tool in molecular and cell biology

Gould, S. J., & Subramani, S. E. (1988) · Analytical Biochemistry · doi:10.1016/0003-2697(88)90353-3 · Cited by 380 · see citing works

A Mutation in the Thyroid Hormone Receptor Alpha Gene

Bochukova, E., Schoenmakers, N., Agostini, M., Schoenmakers, E., Rajanayagam, O., Keogh, J. M., Henning, E., Reinemund, J., Gevers, E., Sarri, M., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1110296 · Cited by 379 · see citing works

Repression of transcription mediated at a thyroid hormone response element by the v-erb-A oncogene product

Sap, J., Múñoz, A., Schmitt, J., Stunnenberg, H. G., & Vennström, B. (1989) · Nature · doi:10.1038/340242a0 · Cited by 378 · see citing works

Cloning of the mammalian type II iodothyronine deiodinase. A selenoprotein differentially expressed and regulated in human and rat brain and other tissues.

Croteau, W., Davey, J. C., Galton, V. A., & Germain, D. L. S. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118806 · Cited by 372 · see citing works

The type 2 iodothyronine deiodinase is expressed primarily in glial cells in the neonatal rat brain

Guadaño-Ferraz, A., Obregón, M. J., Germain, D. L. S., & Bernal, J. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.19.10391 · Cited by 372 · see citing works

Thyroid hormone receptor β is essential for development of auditory function

Forrest, D., Erway, L. C., Ng, L., Altschuler, R. A., & Curran, T. (1996) · Nature Genetics · doi:10.1038/ng0796-354 · Cited by 370 · see citing works

Effects of Maternal Hypothyroidism on the Weight and Thyroid Hormone Content of Rat Embryonic Tissues, before and after Onset of Fetal Thyroid Function*

de Escobar, G. M., PASTOR, R., Obregón, M.-J., & del Rey, F. E. (1985) · Endocrinology · doi:10.1210/endo-117-5-1890 · Cited by 361 · see citing works

Generation of functional thyroid from embryonic stem cells

Antonica, F., Kasprzyk, D. F., Opitz, R., Iacovino, M., Liao, X.-H., Dumitrescu, A. M., Refetoff, S., Peremans, K., Manto, M., Kyba, M., et al. (2012) · Nature · doi:10.1038/nature11525 · Cited by 359 · see citing works

The T3Rα gene encoding a thyroid hormone receptor is essential for post‐natal development and thyroid hormone production

Fraichard, A., Chassande, O., Plateroti, M., Roux, J. P., Trouillas, J., Dehay, C., Legrand, C., Gauthier, K. C., Kédinger, M., Malaval, L., et al. (1997) · The EMBO Journal · doi:10.1093/emboj/16.14.4412 · Cited by 349 · see citing works

Intracellular conversion of thyroxine to triiodothyronine is required for the optimal thermogenic function of brown adipose tissue.

Bianco, A. C., & Silva, J. E. (1987) · Journal of Clinical Investigation · doi:10.1172/jci112798 · Cited by 347 · see citing works

A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone

Glass, C. K., Franco, R., Weinberger, C., Albert, V. R., Evans, R. M., & Rosenfeld, M. G. (1987) · Nature · doi:10.1038/329738a0 · Cited by 346 · see citing works

Type 3 deiodinase is critical for the maturation and function of the thyroid axis

Hernández, A. (2006) · Journal of Clinical Investigation · doi:10.1172/jci26240 · Cited by 344 · see citing works

A new ultrasound instrument for in vivo microimaging of mice

Foster, F. S., Zhang, M. Y., Zhou, Y., Liu, G., Mehi, J., Chérin, E., Harasiewicz, K. A., Starkoski, B. G., Zan, L., Knapik, D. A., et al. (2002) · Ultrasound in Medicine & Biology · doi:10.1016/s0301-5629(02)00567-7 · Cited by 344 · see citing works

Acute Effects of Thyroid Hormone on Vascular Smooth Muscle

Ojamaa, K., Klemperer, J. D., & Klein, I. L. (1996) · Thyroid · doi:10.1089/thy.1996.6.505 · Cited by 342 · see citing works

Thyrotropin-Releasing Hormone Precursor: Characterization in Rat Brain

Lechan, R. M., Wu, P., JACKSON, I. M. D., Wolf, H., Cooperman, S. S., Mandel, G., & Goodman, R. H. (1986) · Science · doi:10.1126/science.3079917 · Cited by 342 · see citing works

Iodide Transport in a Continuous Line of Cultured Cells from Rat Thyroid

WEISS, S. J., Philp, N. J., & Grollman, E. F. (1984) · Endocrinology · doi:10.1210/endo-114-4-1090 · Cited by 341 · see citing works

SPECIFIC NUCLEAR TRIIODOTHYRONINE BINDING SITES IN RAT LIVER AND KIDNEY1

Oppenheimer, J. H., Koerner, D. R., Schwartz, H. L., & Surks, M. I. (1972) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-35-2-330 · Cited by 340 · see citing works

An Analysis of the Sources and Quantity of 3,5,3′-Triiodothyronine Specifically Bound to Nuclear Receptors in Rat Cerebral Cortex and Cerebellum*

CRANTZ, F. R., SILVA, J. E., & LARSEN, P. R. (1982) · Endocrinology · doi:10.1210/endo-110-2-367 · Cited by 340 · see citing works

The TRH neuron: a hypothalamic integrator of energy metabolism

Lechan, R. M., & Fekete, C. (2006) · Progress in brain research · doi:10.1016/s0079-6123(06)53012-2 · Cited by 338 · see citing works

Use of the Thyroid Hormone Analogue Eprotirome in Statin-Treated Dyslipidemia

Ladenson, P. W., Kristensen, J. D., Ridgway, E. C., OLSSON, A. G., Carlsson, B., Klein, I. L., Baxter, J. D., & Angelin, B. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0905633 · Cited by 337 · see citing works

Thyroid hormone regulates TRH biosynthesis in the paraventricular nucleus of the rat hypothalamus

Segerson, T. P., Kauer, J., Wolfe, H. C., Mobtaker, H., Wu, P., Jackson, I. M. D., & Lechan, R. M. (1987) · Science · doi:10.1126/science.3116669 · Cited by 327 · see citing works

A Mutation in the Thyroid Hormone Receptor Alpha Gene

Bochukova, E. G., Schoenmakers, N. A., Agostini, M., Schoenmakers, E., Rajanayagam, O., Keogh, J. M., Henning, E., Reinemund, J., Gevers, E. F., Sarri, M., et al. (2012) · UCL Discovery (University College London) · Cited by 327 · see citing works

Congenital hypothyroidism, as studied in rats. Crucial role of maternal thyroxine but not of 3,5,3'-triiodothyronine in the protection of the fetal brain.

Calvo, R. M., Obregón, M.-J., de Oña, C. R., del Rey, F. E., & de Escobar, G. M. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114790 · Cited by 322 · see citing works

Iodine deficiency and brain development in the first half of pregnancy

de Escobar, G. M., Obregón, M.-J., & del Rey, F. E. (2007) · Public Health Nutrition · doi:10.1017/s1368980007360928 · Cited by 321 · see citing works

PPARγ coactivator-1α expression during thyroid hormone- and contractile activity-induced mitochondrial adaptations

Irrcher, I., Adhihetty, P. J., Sheehan, T. E., Joseph, A.-M., & Hood, D. A. (2003) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00409.2002 · Cited by 315 · see citing works

α-Melanocyte-stimulating hormone is contained in nerve terminals innervating thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and prevents fasting-induced suppression of prothyrotropin-releasing hormone gene expression

Fekete, C., Légrádi, G., Mihály, E., Huang, Q.-H., Tatro, J. B., Rand, W. M., Emerson, C. H., & Lechan, R. M. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-04-01550.2000 · Cited by 308 · see citing works

LXRs regulate the balance between fat storage and oxidation

Kalaany, N. Y., Gauthier, K. C., Zavacki, A. M., Mammen, P. P. A., Kitazume, T., Peterson, J. A., Horton, J. D., Garry, D. J., Bianco, A. C., & Mangelsdorf, D. J. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.03.001 · Cited by 304 · see citing works

Immunohistochemical Profile of the Sodium/Iodide Symporter in Thyroid, Breast, and Other Carcinomas Using High Density Tissue Microarrays and Conventional Sections

Wapnir, I., van de Rijn, M., Nowels, K. W., Amenta, P. S., Walton, K., Montgomery, K. D., Greco, R. S., Dohán, O., & Carrasco, N. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021544 · Cited by 303 · see citing works

Regional distribution of type 2 thyroxine deiodinase messenger ribonucleic acid in rat hypothalamus and pituitary and its regulation by thyroid hormone

Tu, H. M., Kim, S.-W., Salvatore, D., Bartha, T., Legradi, G., Larsen, P. R., & Lechan, R. M. (1997) · Endocrinology · doi:10.1210/endo.138.8.5318 · Cited by 302 · see citing works

Functions of Thyroid Hormone Receptors in Mice

Forrest, D., & Vennström, B. (2000) · Thyroid · doi:10.1089/thy.2000.10.41 · Cited by 298 · see citing works

A Role for Brown Adipose Tissue in Diet‐Induced Thermogenesis

Rothwell, N. J., & Stock, M. J. (1997) · Obesity Research · doi:10.1002/j.1550-8528.1997.tb00591.x · Cited by 296 · see citing works

A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2

Coppola, A., Liu, Z.-W., Andrews, Z. B., Paradis, E., Roy, M.-C., Friedman, J. M., Ricquier, D., Richard, D., Horvath, T. L., Gao, X.-B., et al. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2006.12.002 · Cited by 295 · see citing works

Syndromes of reduced sensitivity to thyroid hormone: genetic defects in hormone receptors, cell transporters and deiodination

Refetoff, S., & Dumitrescu, A. M. (2007) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2007.03.005 · Cited by 294 · see citing works

Replacement therapy for hypothyroidism with thyroxine alone does not ensure euthyroidism in all tissues, as studied in thyroidectomized rats.

Escobar-Morreale, H. F., Obregón, M. J., Escobar del Rey, F., & Morreale de Escobar, G. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118353 · Cited by 287 · see citing works

Beyond Low Plasma T3: Local Thyroid Hormone Metabolism during Inflammation and Infection

Boelen, A., Kwakkel, J., & Fliers, E. (2011) · Endocrine Reviews · doi:10.1210/er.2011-0007 · Cited by 287 · see citing works

Hypothalamic thyroid hormone catabolism acts as a gatekeeper for the seasonal control of body weight and reproduction

Barrett, P., Ebling, F. J. P., Schuhler, S., Wilson, D., Ross, A. W., Warner, A., Jethwa, P., Boelen, A., Visser, T. J., Ozanne, D. M., et al. (2007) · Endocrinology · doi:10.1210/en.2007-0316 · Cited by 286 · see citing works

Effective cellular uptake and efflux of thyroid hormone by human monocarboxylate transporter 10

Friesema, E. C. H., Jansen, J., Jachtenberg, J.-W., Visser, W. E., Kester, M. H. A., & Visser, T. J. (2008) · Molecular Endocrinology · doi:10.1210/me.2007-0112 · Cited by 285 · see citing works

A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor

Chiellini, G., Apriletti, J. W., Yoshihara, H. A. I., Baxter, J. D., Ribeiro, R. C. J., & Scanlan, T. S. (1998) · Chemistry & Biology · doi:10.1016/s1074-5521(98)90168-5 · Cited by 278 · see citing works

Functional relationship of thyroid hormone-induced lipogenesis, lipolysis, and thermogenesis in the rat.

Oppenheimer, J. H., Schwartz, H. L., Lane, J. T., & Thompson, M. P. (1991) · Journal of Clinical Investigation · doi:10.1172/jci114961 · Cited by 278 · see citing works

Targeting thyroid hormone receptor-β agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index

Erion, M. D., Cable, E. E., Ito, B. R., Jiang, H., Fujitaki, J. M., Finn, P. D., Zhang, B., Hou, J., Boyer, S. H., van Poelje, P. D., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702759104 · Cited by 273 · see citing works

Thyroid hormone–sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform–specific

Ribeiro, M. O., Carvalho, S. D., Schultz, J. J., Chiellini, G., Scanlan, T. S., Bianco, A. C., & Brent, G. A. (2001) · Journal of Clinical Investigation · doi:10.1172/jci200112584 · Cited by 271 · see citing works

Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats

Simonides, W. S., Mulcahey, M. A., Redout, E. M., Muller, A., Zuidwijk, M. J., Visser, T. J., Wassen, F. W. J. S., Crescenzi, A., da‐Silva, W. S., Harney, J. W., et al. (2008) · Journal of Clinical Investigation · doi:10.1172/jci32824 · Cited by 270 · see citing works

Mice with a targeted mutation in the thyroid hormone β receptor gene exhibit impaired growth and resistance to thyroid hormone

Kaneshige, M., Kaneshige, K., Zhu, X.-G., Dace, A., Garrett, L. J., Carter, T. A., Kazlauskaite, R., Pankratz, D. G., Wynshaw-Boris, A. J., Refetoff, S., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.230285997 · Cited by 268 · see citing works

The Thyroid Hormone Receptor-β-Selective Agonist GC-1 Differentially Affects Plasma Lipids and Cardiac Activity1

Trost, S. U., Swanson, E., Gloss, B. R., Wang‐Iverson, D. B., Zhang, H., Volodarsky, T., Grover, G. J., Baxter, J. D., Chiellini, G., Scanlan, T. S., et al. (2000) · Endocrinology · doi:10.1210/endo.141.9.7681 · Cited by 268 · see citing works

Targeted Disruption of the Type 1 Selenodeiodinase Gene (Dio1) Results in Marked Changes in Thyroid Hormone Economy in Mice

Schneider, M. J., Fiering, S. N., Thai, B., Wu, S.-Y., St. Germain, E., Parlow, A. F., St. Germain, D. L., & Galton, V. A. (2006) · Endocrinology · doi:10.1210/en.2005-0739 · Cited by 265 · see citing works

Chromatin Immunoprecipitation (ChIP)Preprint

Carey, M., Peterson, C. L., & Smale, S. T. (2009) · Cold Spring Harbor Protocols · doi:10.1101/pdb.prot5279 · Cited by 263 · see citing works

Only the combined treatment with thyroxine and triiodothyronine ensures euthyroidism in all tissues of the thyroidectomized rat.

Escobar-Morreale, H. F., del Rey, F. E., Obregón, M. J., & de Escobar, G. M. (1996) · Endocrinology · doi:10.1210/endo.137.6.8641203 · Cited by 261 · see citing works

Myosin heavy chain isoforms in postnatal muscle development of mice

Agbulut, O., Noirez, P., Beaumont, F., & Butler-Browne, G. S. (2003) · Biology of the Cell · doi:10.1016/s0248-4900(03)00087-x · Cited by 261 · see citing works

Atypical Kinetic Profiles in Drug Metabolism Reactions

Hutzler, J. M., & Tracy, T. S. (2002) · Drug Metabolism and Disposition · doi:10.1124/dmd.30.4.355 · Cited by 261 · see citing works

Mechanisms underlying regional differences in lipolysis in human adipose tissue.

Wahrenberg, H., Lönnqvist, F., & Arner, P. (1989) · Journal of Clinical Investigation · doi:10.1172/jci114187 · Cited by 251 · see citing works

An unliganded thyroid hormone receptor causes severe neurological dysfunction

Hashimoto, K., Curty, F. H., Borges, P. P., Lee, C. E., Abel, E. D., Elmquist, J. K., Cohen, R., & Wondisford, F. E. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.051454698 · Cited by 239 · see citing works

Deletion of the thyroid hormone receptor α1 prevents the structural alterations of the cerebellum induced by hypothyroidism

Morte, B., Manzano, J., Scanlan, T. S., Vennström, B., & Bernal, J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.062413299 · Cited by 227 · see citing works

The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate

Dentice, M., Bandyopadhyay, A., Gereben, B., Callebaut, I., Christoffolete, M. A., Kim, B. W., Nissim, S., Mornon, J.-P., Zavacki, A. M., Zeöld, A., et al. (2005) · Nature Cell Biology · doi:10.1038/ncb1272 · Cited by 227 · see citing works

The Effect of Hepatic Enzyme-Inducing Drugs on Thyroid Hormones and the Thyroid Gland*

CURRAN, P. G., & DEGROOT, L. J. (1991) · Endocrine Reviews · doi:10.1210/edrv-12-2-135 · Cited by 226 · see citing works

Starvation in the rat. II. Effect of age and obesity on protein sparing and fuel metabolism

Goodman, M. N., Larsen, P. R., Kaplan, M. M., Aoki, T. T., Young, V. R., & Ruderman, N. B. (1980) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1980.239.4.e277 · Cited by 223 · see citing works

Anxiety, memory impairment, and locomotor dysfunction caused by a mutant thyroid hormone receptor α1 can be ameliorated by T3 treatmentPreprint

Venero, C., Guadaño‐Ferraz, A., Herrero, A. I., Nordström, K., Manzano, J., de Escobar, G. M., Bernal, J., & Vennström, B. (2005) · Genes & Development · doi:10.1101/gad.346105 · Cited by 222 · see citing works

Clinical Phenotype and Mutant TRα1

van Mullem, A. A., van Heerebeek, R., Chrysis, D., Visser, W. E., Medici, M., Andrikoula, M., Tsatsoulis, A. A., Peeters, R. P., & Visser, T. J. (2012) · New England Journal of Medicine · doi:10.1056/nejmc1113940 · Cited by 221 · see citing works

Selective thyroid hormone receptor-β activation: A strategy for reduction of weight, cholesterol, and lipoprotein (a) with reduced cardiovascular liability

Grover, G. J., Mellström, K., Liu, Y., Malm, J., Li, Y., Bladh, L.-G., Sleph, P. G., Smith, M. A., George, R. J., Vennström, B., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1633737100 · Cited by 221 · see citing works

Tertiary hypothyroidism and hyperglycemia in mice with targeted disruption of the thyrotropin-releasing hormone gene

Yamada, M., Saga, Y., Shibusawa, N., Hirato, J., Murakami, M., Iwasaki, T., Hashimoto, K., Satoh, T., Wakabayashi, K., Taketo, M. M., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.20.10862 · Cited by 217 · see citing works

Thyroid Hormone Transport by the Human Monocarboxylate Transporter 8 and Its Rate-Limiting Role in Intracellular Metabolism

Friesema, E. C. H., Kuiper, G. G. J. M., Jansen, J., Visser, T. J., & Kester, M. H. A. (2006) · Molecular Endocrinology · doi:10.1210/me.2005-0256 · Cited by 214 · see citing works

THYROXINE 5′-DEIODINASE ACTIVITY IN BROWN ADIPOSE TISSUE

Leonard, J. L., MELLEN, S. A., & LARSEN, R. P. (1983) · Endocrinology · doi:10.1210/endo-112-3-1153 · Cited by 213 · see citing works

Mice with Targeted Disruption of the Dio2 Gene Have Cold-Induced Overexpression of the Uncoupling Protein 1 Gene but Fail to Increase Brown Adipose Tissue Lipogenesis and Adaptive Thermogenesis

Christoffolete, M. A., Linardi, C. C. G., de Jesus, L., Ebina, K. N., Carvalho, S. D., Ribeiro, M. O., Rabelo, R., Curcio, C., Martins, L., Kimura, E. T., et al. (2004) · Diabetes · doi:10.2337/diabetes.53.3.577 · Cited by 212 · see citing works

Defining thyrotropin-dependent and -independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice

Marians, R. C., Ng, L., Blair, H. C., Unger, P. D., Graves, P. N., & Davies, T. F. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.242322099 · Cited by 209 · see citing works

Contributions of Plasma Triiodothyronine and Local Thyroxine Monodeiodination to Triiodothyronine to Nuclear Triiodothyronine Receptor Saturation in Pituitary, Liver, and Kidney of Hypothyroid Rats

Silva, J. E., & Larsen, P. R. (1978) · Journal of Clinical Investigation · doi:10.1172/jci109041 · Cited by 209 · see citing works

Thyroid Hormone-Responsive Genes in Developing Cerebellum Include a Novel Synaptotagmin and a hairless Homolog

Thompson, C. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-24-07832.1996 · Cited by 209 · see citing works

Alternate Pathways of Thyroid Hormone Metabolism

Wu, S.-Y., Green, W. L., Huang, W.-S., Hays, M. T., & CHOPRA, I. J. (2005) · Thyroid · doi:10.1089/thy.2005.15.943 · Cited by 207 · see citing works

Thyroid Hormone Regulation of Gene Expression

Williams, G. R. (1994) · Medical Entomology and Zoology · Cited by 206 · see citing works

Triiodothyronine amplifies norepinephrine stimulation of uncoupling protein gene transcription by a mechanism not requiring protein synthesis.

Bianco, A. C., Sheng, X. Y., & Silva, J. E. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)81340-6 · Cited by 206 · see citing works

Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist #

Cable, E. E., Finn, P. D., Stebbins, J. W., Hou, J., Ito, B. R., van Poelje, P. D., Linemeyer, D. L., & Erion, M. D. (2008) · Hepatology · doi:10.1002/hep.22572 · Cited by 206 · see citing works

Developmental and hormonal regulation of sarcomeric myosin heavy chain gene family.

Mahdavi, V., Izumo, S., & Nadal-Ginard, B. (1987) · Circulation Research · doi:10.1161/01.res.60.6.804 · Cited by 202 · see citing works

Thyrotropin- Stimulated Iodide Transport Mediated by Adenosine 3′ 5′-Monophosphate and Dependent on Protein Synthesis

WEISS, S. J., Philp, N. J., Ambesi‐Impiombato, F. S., & Grollman, E. F. (1984) · Endocrinology · doi:10.1210/endo-114-4-1099 · Cited by 201 · see citing works

The sodium iodide symporter: its pathophysiological and therapeutic implications

Spitzweg, C., & Morris, J. C. (2002) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2002.01640.x · Cited by 200 · see citing works

Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice

Johansson, L., Rudling, M. J., Scanlan, T. S., Lundåsen, T., Webb, P., Baxter, J. D., Angelin, B., & Parini, P. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504379102 · Cited by 200 · see citing works

Regulation of Thyroid Hormone Receptor Isoforms in Physiological and Pathological Cardiac Hypertrophy

Kinugawa, K., Yonekura, K., Ribeiro, R. C. J., Eto, Y., Aoyagi, T., Baxter, J. D., Camacho, S. A., Bristow, M. R., Long, C. S., & Simpson, P. C. (2001) · Circulation Research · doi:10.1161/hh1901.096706 · Cited by 199 · see citing works

Regional Expression of the Type 3 Iodothyronine Deiodinase Messenger Ribonucleic Acid in the Rat Central Nervous System and Its Regulation by Thyroid Hormone

Tu, H. M., Légrádi, G., Bartha, T., Salvatore, D., Lechan, R. M., & Larsen, P. R. (1999) · Endocrinology · doi:10.1210/endo.140.2.6486 · Cited by 198 · see citing works

Type 2 iodothyronine deiodinase is highly expressed in human thyroid.

Salvatore, D., Tu, H., Harney, J. W., & Larsen, P. R. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118880 · Cited by 196 · see citing works

Cardiac Ion Channel Expression and Contractile Function in Mice with Deletion of Thyroid Hormone Receptor α or β**This work was supported by Grant HL-25022 (to W.H.D.) and by operating grants from the Canadian Medical Research Council and the Heart and Stroke Foundation of Canada (to W.G. and R.C.).

Gloss, B. R., Trost, S. U., Bluhm, W. F., Swanson, E. A., Clark, R., Winkfein, R. J., Janzen, K. M., Giles, W. R., Chassande, O., Samarut, J., et al. (2001) · Endocrinology · doi:10.1210/endo.142.2.7935 · Cited by 195 · see citing works

Critical role for thyroid hormone receptor β2 in the regulation of paraventricular thyrotropin-releasing hormone neurons

Abel, E. D., Ahima, R. S., Boers, M.-E., Elmquist, J. K., & Wondisford, F. E. (2001) · Journal of Clinical Investigation · doi:10.1172/jci10858 · Cited by 192 · see citing works

The thyroid hormone mimetic compound KB2115 lowers plasma LDL cholesterol and stimulates bile acid synthesis without cardiac effects in humans

Berkenstam, A. L., Kristensen, J. D., Mellström, K., Carlsson, B., Malm, J., Rehnmark, S., Garg, N. K., Andersson, C., Rudling, M. J., Sjöberg, F., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705286104 · Cited by 191 · see citing works

Multiple Mechanisms for Regulation of the Transcriptional Activity of Thyroid Hormone Receptors

Cheng, S.-Y. (2000) · Reviews in Endocrine and Metabolic Disorders · doi:10.1023/a:1010052101214 · Cited by 190 · see citing works

Pathways of thyroid hormone metabolism.

Visser, T. J. (1996) · PubMed · Cited by 190 · see citing works

The Contribution of Local Tissue Thyroxine Monodeiodination to the Nuclear 3,5,3′- Triiodothyronine in Pituitary, Liver, and Kidney of Euthyroid Rats*

SILVA, J. E., DICK, T. E., & LARSEN, P. R. (1978) · Endocrinology · doi:10.1210/endo-103-4-1196 · Cited by 189 · see citing works

Thyroid Hormone Acts Directly on Growth Plate Chondrocytes to Promote Hypertrophic Differentiation and Inhibit Clonal Expansion and Cell Proliferation¹

Robson, H., Siebler, T., Stevens, D. A., Shalet, S. M., & Williams, G. R. (2000) · Endocrinology · doi:10.1210/endo.141.10.7733 · Cited by 188 · see citing works

The Na + /I − symporter (NIS) mediates electroneutral active transport of the environmental pollutant perchlorate

Dohán, O., Portulano, C., Basquin, C., Reyna‐Neyra, A., Amzel, L. M., & Carrasco, N. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0707207104 · Cited by 187 · see citing works

THYROID HORMONE REGULATION OF GENE EXPRESSION

Brent, G. A., Moore, D. D., & Larsen, R. P. (1991) · Annual Review of Physiology · doi:10.1146/annurev.ph.53.030191.000313 · Cited by 186 · see citing works

Thyroid Hormone Action: A Cell-Culture System Responsive to Physiological Concentrations of Thyroid Hormones

Samuels, H. H., Tsai, J. S., & Cintron, R. (1973) · Science · doi:10.1126/science.181.4106.1253 · Cited by 184 · see citing works

Triiodothyronine (T3) decreases binding to DNA by T3-receptor homodimers but not receptor-auxiliary protein heterodimers.

Yen, P. M., Darling, D. S., Carter, R. L., Forgione, M. A., Umeda, P. K., & Chin, W. W. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)50559-2 · Cited by 181 · see citing works

Expression of Type 2 Iodothyronine Deiodinase in Hypothyroid Rat Brain Indicates an Important Role of Thyroid Hormone in the Development of Specific Primary Sensory Systems

Guadaño‐Ferraz, A., Escamez, M. J., Rausell, E., & Bernal, J. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-09-03430.1999 · Cited by 180 · see citing works

Lipopolysaccharide Induces Type 2 Iodothyronine Deiodinase in the Mediobasal Hypothalamus: Implications for the Nonthyroidal Illness Syndrome

Fekete, C., Gereben, B., Doleschall, M., Harney, J. W., Dora, J. M., Bianco, A. C., Sarkar, S., Liposits, Z., Rand, W., Emerson, C., et al. (2004) · Endocrinology · doi:10.1210/en.2003-1439 · Cited by 179 · see citing works

Subcellular localization of a rat liver enzyme converting thyroxine into tri-iodothyronine and possible involvement of essential thiol groups

Visser, T. J., Does-Tobé, I. V. D., Docter, R., & HENNEMANN, G. (1976) · Biochemical Journal · doi:10.1042/bj1570479 · Cited by 176 · see citing works

The quantitative contributions of mitochondrial proton leak and ATP turnover reactions to the changed respiration rates of hepatocytes from rats of different thyroid status

Harper, M., & Brand, M. D. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)82411-5 · Cited by 174 · see citing works

Thyroid Hormone Homeostasis and Action in the Type 2 Deiodinase-Deficient Rodent Brain during Development

Galton, V. A., Wood, E. T., Germain, E. A. S., Withrow, C.-A., Aldrich, G., Germain, G. M. S., Clark, A. S., & Germain, D. L. S. (2007) · Endocrinology · doi:10.1210/en.2006-1727 · Cited by 174 · see citing works

Characteristics of mitochondria isolated from type I and type IIb skeletal muscle

Jackman, M. R., & Willis, W. T. (1996) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1996.270.2.c673 · Cited by 173 · see citing works

An assay for sarcoplasmic reticulum Ca2+-ATPase activity in muscle homogenates

Simonides, W. S., & van Hardeveld, C. (1990) · Analytical Biochemistry · doi:10.1016/0003-2697(90)90226-y · Cited by 173 · see citing works

Rapid Effects of Single Small Doses of L-Thyroxine and Triiodo-L-thyronine on Growth Hormone, as Studied in the Rat by Radioimmunoassay1

Hervás, F., de Escobar, G. M., & del Rey, F. E. (1975) · Endocrinology · doi:10.1210/endo-97-1-91 · Cited by 173 · see citing works

The FoxO3/type 2 deiodinase pathway is required for normal mouse myogenesis and muscle regeneration

Dentice, M., Marsili, A., Ambrosio, R., Guardiola, O., Sibilio, A., Paik, J.-H., Minchiotti, G., DePinho, R. A., Fenzi, G., Larsen, P. R., et al. (2010) · Journal of Clinical Investigation · doi:10.1172/jci43670 · Cited by 173 · see citing works

Thyroid Hormone Regulates reelin and dab1Expression During Brain Development

Álvarez‐Dolado, M., Ruiz, M., del Rı́o, J. A., Alcántara, S., Burgaya, F., Sheldon, M., Nakajima, K., Bernal, J., Howell, B. W., Curran, T., et al. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-16-06979.1999 · Cited by 171 · see citing works

A Thyroid Hormone Receptor α Gene Mutation (P398H) Is Associated with Visceral Adiposity and Impaired Catecholamine-stimulated Lipolysis in Mice

Liu, Y., Schultz, J. J., & Brent, G. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m306120200 · Cited by 168 · see citing works

Thyroid Hormone as a Determinant of Metabolic and Contractile Phenotype of Skeletal Muscle

Simonides, W. S., & van Hardeveld, C. (2008) · Thyroid · doi:10.1089/thy.2007.0256 · Cited by 168 · see citing works

Neuropeptide Y has a central inhibitory action on the hypothalamic-pituitary-thyroid axis

Fekete, C., Kelly, J., Mihály, E., Sarkar, S., Rand, W. M., Légrádi, G., Emerson, C. H., & Lechan, R. M. (2001) · Endocrinology · doi:10.1210/endo.142.6.8207 · Cited by 167 · see citing works

Type 3 Deiodinase, a Thyroid-Hormone-Inactivating Enzyme, Controls Survival and Maturation of Cone Photoreceptors

Ng, L., Lyubarsky, A., Nikonov, S. S., Ma, M., Srinivas, M., Kefas, B. A., Germain, D. L. S., Hernández, A., Pugh, E. N., & Forrest, D. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.5267-09.2010 · Cited by 167 · see citing works

Hormone Selectivity in Thyroid Hormone Receptors

Wagner, R., Huber, B. R., Shiau, A. K., Kelly, A. E., Lima, S. T. D. C., Scanlan, T. S., Apriletti, J. W., Baxter, J. D., West, B. L., & Fletterick, R. J. (2001) · Molecular Endocrinology · doi:10.1210/mend.15.3.0608 · Cited by 167 · see citing works

Thyroid Hormone Excess Rather Than Thyrotropin Deficiency Induces Osteoporosis in Hyperthyroidism

Bassett, J. H. D., O’Shea, P. J., Sriskantharajah, S., Rabier, B., Boyde, A., Howell, P. G. T., Weiss, R. E., Roux, J.-P., Malaval, L., Clement-Lacroix, P., et al. (2007) · Molecular Endocrinology · doi:10.1210/me.2007-0033 · Cited by 167 · see citing works

Stable expression of the human TSH receptor in CHO cells and characterization of differentially expressing clones

Perret, J., Ludgate, M. E., Libert, F., Gerard, C. M., Dumont, J. E., Vassart, G., & Parmentier, M. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(90)90789-p · Cited by 164 · see citing works

A Protective Role for Type 3 Deiodinase, a Thyroid Hormone-Inactivating Enzyme, in Cochlear Development and Auditory Function

Ng, L., Hernández, A., He, W., Ren, T., Srinivas, M., Ma, M., Galton, V. A., Germain, D. L. S., & Forrest, D. (2008) · Endocrinology · doi:10.1210/en.2008-1419 · Cited by 164 · see citing works

Triiodothyronine Stimulates Food Intake via the Hypothalamic Ventromedial Nucleus Independent of Changes in Energy Expenditure

Kong, W. M., Martin, N. M., Smith, K. L., Gardiner, J., Connoley, I. P., Stephens, D. A., Dhillo, W. S., Ghatei, M. A., Small, C. J., & Bloom, S. R. (2004) · Endocrinology · doi:10.1210/en.2004-0545 · Cited by 164 · see citing works

Changes in the hepatic levels of messenger ribonucleic acid for malic enzyme during induction by thyroid hormone or diet

Towle, H. C., Mariash, C. N., & Oppenheimer, J. H. (1980) · Biochemistry · doi:10.1021/bi00544a029 · Cited by 161 · see citing works

Selective Proteolysis of Human Type 2 Deiodinase: A Novel Ubiquitin-Proteasomal Mediated Mechanism for Regulation of Hormone Activation

Gereben, B., Goncalves, C., Harney, J. W., Larsen, P. R., & Bianco, A. C. (2000) · Molecular Endocrinology · doi:10.1210/mend.14.11.0558 · Cited by 161 · see citing works

Effects of the Thyroid Hormone Receptor Agonist GC-1 on Metabolic Rate and Cholesterol in Rats and Primates: Selective Actions Relative to 3,5,3′-Triiodo- l -Thyronine

Grover, G. J., Egan, D. M., Sleph, P. G., Beehler, B. C., Chiellini, G., Nguyen, N.-H., Baxter, J. D., & Scanlan, T. S. (2004) · Endocrinology · doi:10.1210/en.2003-0973 · Cited by 161 · see citing works

Thyroid hormone stimulates NO production via activation of the PI3K/Akt pathway in vascular myocytes

Carrillo-Sepúlveda, M. A., Ceravolo, G. S., Fortes, Z. B., de Carvalho, M. H. C., Tostes, R. C., Laurindo, F. R. M., Webb, R. C., & Barreto‐Chaves, M. L. M. (2009) · Cardiovascular Research · doi:10.1093/cvr/cvp304 · Cited by 160 · see citing works

Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells

Freitas, B. C. G., Gereben, B., Castillo, M., Kalló, I., Zeöld, A., Egri, P., Liposits, Z., Zavacki, A. M., Maciel, R. M. B., Jo, S., et al. (2010) · Journal of Clinical Investigation · doi:10.1172/jci41977 · Cited by 160 · see citing works

EMPReSS: standardized phenotype screens for functional annotation of the mouse genome

Brown, S. D. M., Chambon, P., & de Angelis, M. H. (2005) · Nature Genetics · doi:10.1038/ng1105-1155 · Cited by 159 · see citing works

Simultaneous changes in central and peripheral components of the hypothalamus-pituitary-thyroid axis in lipopolysaccharide-induced acute illness in mice

Boelen, A., Kwakkel, J., Thijssen-Timmer, D., Alkemade, A., Fliers, E., & Wiersinga, W. (2004) · Journal of Endocrinology · doi:10.1677/joe.0.1820315 · Cited by 159 · see citing works

Thyroid hormone receptors in chick retinal development: differential expression of mRNAs for α and N-terminal variant β receptors

Sjöberg, M., Vennström, B., & Forrest, D. (1992) · Development · doi:10.1242/dev.114.1.39 · Cited by 155 · see citing works

Patterns of Liver Gene Expression Governed by TRβ

Flores‐Morales, A., Gullberg, H., Fernández‐Pérez, L., Ståhlberg, N., Lee, N. H., Vennström, B., & Norstedt, G. (2002) · Molecular Endocrinology · doi:10.1210/mend.16.6.0846 · Cited by 154 · see citing works

Improved Radioimmunoassay for Measurement of Mouse Thyrotropin in Serum: Strain Differences in Thyrotropin Concentration and Thyrotroph Sensitivity to Thyroid Hormone

Pohlenz, J., MAQUEEM, A., Cua, K., Weiss, R. E., SANDE, J. V., & Refetoff, S. (1999) · Thyroid · doi:10.1089/thy.1999.9.1265 · Cited by 154 · see citing works

Mutations of the PDS Gene, Encoding Pendrin, Are Associated with Protein Mislocalization and Loss of Iodide Efflux: Implications for Thyroid Dysfunction in Pendred Syndrome

Taylor, J. P., Metcalfe, R., Watson, P. F., Weetman, A. P., & Trembath, R. C. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.4.8435 · Cited by 154 · see citing works

Plasma Lipoproteins and Regulation of Hepatic Metabolism of Fatty Acids in Altered Thyroid States*

Heimberg, M., Olubadewo, J. O., & Wilcox, H. G. (1985) · Endocrine Reviews · doi:10.1210/edrv-6-4-590 · Cited by 153 · see citing works

Pregnant rat uterus expresses high levels of the type 3 iodothyronine deiodinase

Galton, V. A., Martinez, E., Hernández, A., Germain, E. A. S., Bates, J. M., & Germain, D. L. S. (1999) · Journal of Clinical Investigation · doi:10.1172/jci6073 · Cited by 152 · see citing works

Altered relationship between protonmotive force and respiration rate in non‐phosphorylating liver mitochondria isolated from rats of different thyroid hormone status

Hafner, R. P., Nobes, C. D., McGown, A. D., & Brand, M. D. (1988) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1988.tb14477.x · Cited by 151 · see citing works

Synergism of thyroid hormone and high carbohydrate diet in the induction of lipogenic enzymes in the rat. Mechanisms and implications.

Mariash, C. N., Kaiser, F. E., Schwartz, H. L., Towle, H. C., & Oppenheimer, J. H. (1980) · Journal of Clinical Investigation · doi:10.1172/jci109766 · Cited by 150 · see citing works

Type II and type III deiodinase activity in human placenta as a function of gestational age

Koopdonk-Kool, J. M., de Vijlder, J. J. M., Veenboer, G. J. M., Ris‐Stalpers, C., Kok, J. H., Vulsma, T., Boer, K., & Visser, T. J. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.6.8964844 · Cited by 149 · see citing works

Molecular or Pharmacologic Perturbation of the Link between Glucose and Lipid Metabolism Is without Effect on Glucose-stimulated Insulin Secretion

Antinozzi, P. A., Segall, L., Prentki, M., McGarry, J., & Newgard, C. B. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.26.16146 · Cited by 149 · see citing works

Functional Characterization of Pendrin in a Polarized Cell System

Gillam, M. P., Sidhaye, A. R., Lee, E. J., Rutishauser, J., Stephan, C. W., & Kopp, P. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m313648200 · Cited by 149 · see citing works

The Slc26a4 transporter functions as an electroneutral Cl−/I−/HCO3− exchanger: role of Slc26a4 and Slc26a6 in I− and HCO3− secretion and in regulation of CFTR in the parotid duct

Shcheynikov, N., Yang, D., Wang, Y., Zeng, W., Karniski, L. P., So, I., Wall, S. M., & Muallem, S. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2008.154468 · Cited by 148 · see citing works

Type 2 iodothyronine deiodinase expression in the cochlea before the onset of hearing

Campos‐Barros, Á., Amma, L. L., Faris, J. S., Shailam, R., Kelley, M. W., & Forrest, D. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.3.1287 · Cited by 148 · see citing works

Pathophysiological Importance of Thyroid Hormone Transporters

Heuer, H., & Visser, T. J. (2009) · Endocrinology · doi:10.1210/en.2008-1518 · Cited by 148 · see citing works

Effects of Neonatal Hypothyroidism on Rat Brain Gene Expression

Múñoz, A., Rodríguez‐Peña, A., Pérez‐Castillo, A., Ferreiro, B., Sutcliffe, J. G., & Bernal, J. (1991) · Molecular Endocrinology · doi:10.1210/mend-5-2-273 · Cited by 148 · see citing works

Ontogeny of Iodothyronine Deiodinases in Human Liver1

Richard, K., Hume, R., Kaptein, E., Sanders, J. P., van Toor, H., de Herder, W. W., den Hollander, J. C., Krenning, E. P., & Visser, T. J. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.8.5032 · Cited by 147 · see citing works

Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement

Jonklaas, J., Bianco, A. C., Bauer, A. J., Burman, K. D., Cappola, A. R., Celi, F. S., Cooper, D. S., Kim, B. W., Peeters, R. P., Rosenthal, M. S., et al. (2014) · Thyroid® · doi:10.1089/thy.2014.0028 · Cited by 1,928 · see citing works

Paradigms of dynamic control of thyroid hormone signaling

Bianco, A. C., Dumitrescu, A., Gereben, B., Ribeiro, M. O., Fonseca, T. L., Fernandes, G. W., & Bocco, B. M. L. C. (2019) · Endocrine Reviews · doi:10.1210/er.2018-00275 · Cited by 293 · see citing works

Nonalcoholic Fatty Liver Disease and Hypercholesterolemia: Roles of Thyroid Hormones, Metabolites, and Agonists

Sinha, R. A., Bruinstroop, E., Singh, B. K., & Yen, P. M. (2019) · Thyroid · doi:10.1089/thy.2018.0664 · Cited by 272 · see citing works

Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine

Werneck de Castro, J. P., Fonseca, T. L., Ueta, C. B., McAninch, E. A., Abdalla, S., Wittmann, G., Lechan, R. M., Gereben, B., & Bianco, A. C. (2015) · Journal of Clinical Investigation · doi:10.1172/jci77588 · Cited by 184 · see citing works

Defending plasma T3 is a biological priority

Abdalla, S. M., & Bianco, A. C. (2014) · Clinical Endocrinology · doi:10.1111/cen.12538 · Cited by 147 · see citing works

Scope and limitations of iodothyronine deiodinases in hypothyroidism

Gereben, B., McAninch, E. A., Ribeiro, M. O., & Bianco, A. C. (2015) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2015.155 · Cited by 146 · see citing works

Triiodothyronine prevents cardiac ischemia/reperfusion mitochondrial impairment and cell loss by regulating miR30a/p53 axis

Forini, F., Kusmic, C., Nicolini, G., Mariani, L., Zucchi, R., Matteucci, M., Iervasi, G., & Pitto, L. (2014) · Endocrinology · doi:10.1210/en.2014-1106 · Cited by 132 · see citing works

Assessing dose–response relationships for endocrine disrupting chemicals (EDCs): a focus on non-monotonicity

Zoeller, R. T., & Vandenberg, L. N. (2015) · Environmental Health · doi:10.1186/s12940-015-0029-4 · Cited by 130 · see citing works

60 YEARS OF NEUROENDOCRINOLOGY: TRH, the first hypophysiotropic releasing hormone isolated: control of the pituitary–thyroid axis

Joseph‐Bravo, P., Jaimes-Hoy, L., Uribe, R.-M., & Charli, J. (2015) · Journal of Endocrinology · doi:10.1530/joe-15-0124 · Cited by 107 · see citing works

Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain

Jo, S., Fonseca, T. L., Bocco, B. M. L. C., Fernandes, G. W., McAninch, E. A., Bolin, A. P., Da Conceição, R. R., Werneck-de-Castro, J. P., Ignacio, D. L., Egri, P., et al. (2018) · Journal of Clinical Investigation · doi:10.1172/jci123176 · Cited by 107 · see citing works

Thyroid-Hormone-Induced Browning of White Adipose Tissue Does Not Contribute to Thermogenesis and Glucose Consumption

Johann, K., Cremer, A. L., Fischer, A. W., Heine, M., Pensado, E. R., Resch, J., Nock, S., Virtue, S., Harder, L., Oelkrug, R., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.05.054 · Cited by 107 · see citing works

Myelin repair stimulated by CNS-selective thyroid hormone action

Hartley, M. D., Banerji, T., Tagge, I., Kirkemo, L. L., Chaudhary, P., Calkins, E., Galipeau, D., Shokat, M. D., DeBell, M. J., Leuven, S. V., et al. (2019) · JCI Insight · doi:10.1172/jci.insight.126329 · Cited by 100 · see citing works

The Deiodinase Trio and Thyroid Hormone Signaling

Bianco, A. C., & da Conceição, R. R. (2018) · Methods in Molecular Biology · doi:10.1007/978-1-4939-7902-8_8 · Cited by 96 · see citing works

Prevalent Polymorphism in Thyroid Hormone-Activating Enzyme Leaves a Genetic Fingerprint That Underlies Associated Clinical Syndromes

McAninch, E. A., Jo, S., Preite, N. Z., Farkas, E., Mohácsik, P., Fekete, C., Egri, P., Gereben, B., Li, Y., Deng, Y., et al. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-4092 · Cited by 93 · see citing works

Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice

Weiner, J., Kranz, M., Klöting, N., Kunath, A., Steinhoff, K. G., Rijntjes, E., Köhrle, J., Zeisig, V., Hankir, M. K., Gebhardt, C., et al. (2016) · Scientific Reports · doi:10.1038/srep38124 · Cited by 92 · see citing works

Human longevity is characterised by high thyroid stimulating hormone secretion without altered energy metabolism

Jansen, S. W., Akintola, A. A., Roelfsema, F., van der Spoel, E., Cobbaert, C. M., Ballieux, B. E., Egri, P., Kvarta-Papp, Z., Gereben, B., Fekete, C., et al. (2015) · Scientific Reports · doi:10.1038/srep11525 · Cited by 82 · see citing works

60 YEARS OF NEUROENDOCRINOLOGY: TRH, the first hypophysiotropic releasing hormone isolated: control of the pituitary–thyroid axis

Joseph‐Bravo, P., Jaimes-Hoy, L., Uribe, R.-M., & Charli, J. (2015) · Journal of Endocrinology · doi:10.1530/joe-15-0124e · Cited by 81 · see citing works

A Thyroid Hormone–Based Strategy for Correcting the Biochemical Abnormality in X-Linked Adrenoleukodystrophy

Hartley, M. D., Kirkemo, L. L., Banerji, T., & Scanlan, T. S. (2017) · Endocrinology · doi:10.1210/en.2016-1842 · Cited by 71 · see citing works

Tissue-Specific Inactivation of Type 2 Deiodinase Reveals Multilevel Control of Fatty Acid Oxidation by Thyroid Hormone in the Mouse

Fonseca, T. L., Werneck‐de‐Castro, J. P., Castillo, M., Bocco, B. M. L. C., Fernandes, G. W., McAninch, E. A., Ignacio, D. L., Moises, C., Ferreira, A. R., Gereben, B., et al. (2014) · Diabetes · doi:10.2337/db13-1768 · Cited by 64 · see citing works

Type 2 Deiodinase Disruption in Astrocytes Results in Anxiety-Depressive-Like Behavior in Male Mice

Bocco, B. M. L. C., Werneck‐de‐Castro, J. P., Oliveira, K. C., Fernandes, G. W., Fonseca, T. L., do Nascimento, B. P. P., McAninch, E. A., Ricci, E. L., Kvárta-Papp, Z., Fekete, C., et al. (2016) · Endocrinology · doi:10.1210/en.2016-1272 · Cited by 63 · see citing works

Sex-specific phenotypes of hyperthyroidism and hypothyroidism in mice

Rakov, H., Engels, K., Hönes, G. S., Strucksberg, K.-H., Moeller, L. C., Köhrle, J., Zwanziger, D., & Führer, D. (2016) · Biology of Sex Differences · doi:10.1186/s13293-016-0089-3 · Cited by 61 · see citing works

Levothyroxine: conventional and novel drug delivery formulations.

Liu, H., Li, W., Zhang, W., Sun, S., & Chen, C. (2023) · Endocrine Reviews · doi:10.1210/endrev/bnac030 · Cited by 63 · see citing works

Thyroid hormone activation by type 2 deiodinase mediates exercise‐induced peroxisome proliferator‐activated receptor‐γ coactivator‐1α expression in skeletal muscle

Bocco, B. M. L. C., Louzada, R. A. N., Silvestre, D. H., Santos, M. C. S., Anne‐Palmer, E., Rangel, I. F., Abdalla, S. M., Ferreira, A. C. F., Ribeiro, M. O., Gereben, B., et al. (2016) · The Journal of Physiology · doi:10.1113/jp272440 · Cited by 55 · see citing works

Adult neural stem cell fate is determined by thyroid hormone activation of mitochondrial metabolism

Gothié, J. M., Sébillot, A., Luongo, C., Legendre, M., Van, C. N., Blay, K. L., Perret-Jeanneret, M., Remaud, S., & DEMENEIX, B. A. (2017) · Molecular Metabolism · doi:10.1016/j.molmet.2017.08.003 · Cited by 53 · see citing works

Plant constituents and thyroid: A revision of the main phytochemicals that interfere with thyroid function

Dalmazi, G. D., & Giuliani, C. (2021) · Food and Chemical Toxicology · doi:10.1016/j.fct.2021.112158 · Cited by 55 · see citing works

New insights for male infertility revealed by alterations in spermatic function and differential testicular expression of thyroid-related genes

Romano, R. M., Gomes, S. N., Cardoso, N. C. S., Schiessl, L., Romano, M. A., & de Oliveira, C. A. (2016) · Endocrine · doi:10.1007/s12020-016-0952-3 · Cited by 52 · see citing works

Thyroid Hormone Receptor α Mutation Causes a Severe and Thyroxine-Resistant Skeletal Dysplasia in Female Mice

Bassett, J. H. D., Boyde, A., Zikmund, T., Evans, H., Croucher, P. I., Zhu, X., Park, J. W., Cheng, S.-Y., & Williams, G. R. (2014) · Endocrinology · doi:10.1210/en.2013-2156 · Cited by 50 · see citing works

Disruption of Type 2 Iodothyronine Deiodinase Activity in Cultured Human Glial Cells by Polybrominated Diphenyl Ethers

Roberts, S. C., Bianco, A. C., & Stapleton, H. M. (2015) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.5b00072 · Cited by 49 · see citing works

Cadmium exposure promotes thyroid pyroptosis and endocrine dysfunction by inhibiting Nrf2/Keap1 signaling

Chen, Y., Zhou, C., Bian, Y., Fu, F., Zhu, B., Zhao, X., Zhang, M., Zhou, C., Yao, S., Zhang, Z., et al. (2022) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2022.114376 · Cited by 46 · see citing works

Role of hepatic deiodinases in thyroid hormone homeostasis and liver metabolism, inflammation, and fibrosis

Bruinstroop, E., van der Spek, A. H., & Boelen, A. (2023) · European Thyroid Journal · doi:10.1530/etj-22-0211 · Cited by 51 · see citing works

Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity

Fonseca, T. L., Fernandes, G. W., McAninch, E. A., Bocco, B. M. L. C., Abdalla, S. M., Ribeiro, M. O., Mohácsik, P., Fekete, C., Li, D., Xing, X., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1508943112 · Cited by 46 · see citing works

Effects of growth hormone on thyroid function are mediated by type 2 iodothyronine deiodinase in humans

Yamauchi, I., Sakane, Y., Yamashita, T., Hirota, K., Ueda, Y., Kanai, Y., Yamashita, Y., Kondo, E., Fujii, T., Taura, D., et al. (2017) · Endocrine · doi:10.1007/s12020-017-1495-y · Cited by 46 · see citing works

A High‐Fat Diet Rich in Saturated and Mono‐Unsaturated Fatty Acids Induces Disturbance of Thyroid Lipid Profile and Hypothyroxinemia in Male Rats

Zhang, X., Chen, W., Shao, S., Xu, G., Song, Y., Xu, C., Gao, L., Hu, C., & Zhao, J. (2018) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201700599 · Cited by 44 · see citing works

Toxicity of Hexamoll® DINCH® following intravenous administration

David, R. M., White, R. D., Larson, M. J., Herman, J. K., & Otter, R. (2015) · Toxicology Letters · doi:10.1016/j.toxlet.2015.07.013 · Cited by 43 · see citing works

Coupling between Nutrient Availability and Thyroid Hormone Activation

Lartey, L. J., Werneck-de-Castro, J. P., O-Sullivan, I., Unterman, T. G., & Bianco, A. C. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.665505 · Cited by 41 · see citing works

Oligomerization of GPCRs involved in endocrine regulation

Kleinau, G., Müller, A., & Biebermann, H. (2016) · Journal of Molecular Endocrinology · doi:10.1530/jme-16-0049 · Cited by 39 · see citing works

Thyroid Hormone-Regulated Cardiac microRNAs are Predicted to Suppress Pathological Hypertrophic Signaling

Janssen, R., Zuidwijk, M. J., Kuster, D. W. D., Muller, A., & Simonides, W. S. (2014) · Frontiers in Endocrinology · doi:10.3389/fendo.2014.00171 · Cited by 37 · see citing works

Inactivation of the adrenergic receptor β2 disrupts glucose homeostasis in mice

Fernandes, G. W., Ueta, C. B., Fonseca, T. L., Gouveia, C. H. D. A., Lancellotti, C. L. P., Brum, P. C., Christoffolete, M. A., Bianco, A. C., & Ribeiro, M. O. (2014) · Journal of Endocrinology · doi:10.1530/joe-13-0526 · Cited by 36 · see citing works

Antithyroid Drug Use in Pregnancy and Birth Defects: Why Some Studies Find Clear Associations, and Some Studies Report None

Laurberg, P., & Andersen, S. L. (2015) · Thyroid · doi:10.1089/thy.2015.0182 · Cited by 35 · see citing works

Disruption of beta3 adrenergic receptor increases susceptibility to DIO in mouse

Preite, N. Z., do Nascimento, B. P. P., Muller, C. R., Américo, A. L. V., Higa, T. S., Evangelista, F. S., Lancellotti, C. L. P., Henriques, F. D. S., Júnior, M. L. B., Bianco, A. C., et al. (2016) · Journal of Endocrinology · doi:10.1530/joe-16-0199 · Cited by 35 · see citing works

An extremely high dietary iodide supply forestalls severe hypothyroidism in Na+/I− symporter (NIS) knockout mice

Ferrandino, G., Kaspari, R. R., Reyna‐Neyra, A., Boutagy, N. E., Sinusas, A. J., & Carrasco, N. (2017) · Scientific Reports · doi:10.1038/s41598-017-04326-z · Cited by 35 · see citing works

ER stress contributes to high-fat diet-induced decrease of thyroglobulin and hypothyroidism

Zhang, X., Shao, S., Zhao, L., Yang, R., Zhao, M., Li, F., Li, M., Chen, W., Song, Y., Xu, C., et al. (2019) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00194.2018 · Cited by 35 · see citing works

Parallel Regulation of Thyroid Hormone Transporters OATP1c1 and MCT8 During and After Endotoxemia at the Blood-Brain Barrier of Male Rodents

Wittmann, G., Szabon, J., Mohácsik, P., Nouriel, S. S., Gereben, B., Fekete, C., & Lechan, R. M. (2015) · Endocrinology · doi:10.1210/en.2014-1830 · Cited by 35 · see citing works

Practical considerations for developmental thyroid toxicity assessments: What's working, what's not, and how can we do better?

Li, A. A., Makris, S. L., Marty, M. S., Strauss, V., Gilbert, M. E., Blacker, A. M., Zorrilla, L. M., Coder, P. S., Hannas, B. R., Lordi, S., et al. (2019) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2019.04.010 · Cited by 34 · see citing works

The environmental contaminant tributyltin leads to abnormalities in different levels of the hypothalamus-pituitary-thyroid axis in female rats

Andrade, M. N., Santos-Silva, A. P., Rodrigues-Pereira, P., Paiva-Melo, F. D., Lima-Junior, N. C., Teixeira, M. P., Soares, P., Dias, G. R. M., Graceli, J. B., de Carvalho, D. P., et al. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2018.06.006 · Cited by 34 · see citing works

Desensitization and Incomplete Recovery of Hepatic Target Genes After Chronic Thyroid Hormone Treatment and Withdrawal in Male Adult Mice

Ohba, K., Leow, M. K., Singh, B. K., Sinha, R. A., Lesmana, R., Liao, X.-H., Ghosh, S., Refetoff, S., Sng, J., & Yen, P. M. (2016) · Endocrinology · doi:10.1210/en.2015-1848 · Cited by 33 · see citing works

Axonal T3 uptake and transport can trigger thyroid hormone signaling in the brain

Salas-Lucia, F., Fekete, C., Sinkó, R., Egri, P., Rada, K., Ruska, Y., Gereben, B., & Bianco, A. C. (2023) · eLife · doi:10.7554/elife.82683 · Cited by 33 · see citing works

Sustained release T3 therapy: animal models and translational applications

Idrees, T., Price, J. D., Piccariello, T., & Bianco, A. C. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00544 · Cited by 30 · see citing works

Development of anIn VitroHuman Thyroid Microtissue Model for Chemical Screening

Deisenroth, C., Soldatow, V. Y., Ford, J., Stewart, W. M., Brinkman, C. L., LeCluyse, E. L., MacMillan, D. K., & Thomas, R. S. (2019) · Toxicological Sciences · doi:10.1093/toxsci/kfz238 · Cited by 32 · see citing works

American Thyroid Association Guidelines and Statements: Past, Present, and Future: American Thyroid Association Guidelines Policy and Procedures Task Force

Sawka, A. M., Carty, S. E., Haugen, B. R., Hennessey, J. V., Kopp, P. A., Pearce, E. N., Sosa, J. A., Tufano, R. P., & Jonklaas, J. (2018) · Thyroid · doi:10.1089/thy.2018.0070 · Cited by 35 · see citing works

Thyroid wars: the rise of central actions

Capelli, V., Diéguez, C., Mittag, J., & López, M. (2021) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2021.05.006 · Cited by 31 · see citing works

Maternal hypothyroidism: An overview of current experimental models

Ghanbari, M., & Ghasemi, A. (2017) · Life Sciences · doi:10.1016/j.lfs.2017.08.012 · Cited by 30 · see citing works

Investigation of adrenal and thyroid gland dysfunction in dogs with ultrasonographic diagnosis of gallbladder mucocele formation

Aicher, K. M., Cullen, J. M., Seiler, G. S., Lunn, K. F., Mathews, K. G., & Gookin, J. L. (2019) · PLoS ONE · doi:10.1371/journal.pone.0212638 · Cited by 29 · see citing works

Deletion of the Thyroid Hormone–Activating Type 2 Deiodinase Rescues Cone Photoreceptor Degeneration but Not Deafness in Mice Lacking Type 3 Deiodinase

Ng, L., Liu, H., Germain, D. L. S., Hernández, A., & Forrest, D. (2017) · Endocrinology · doi:10.1210/en.2017-00055 · Cited by 28 · see citing works

Chronic infusion of taurolithocholate into the brain increases fat oxidation in mice

Eggink, H. M., Tambyrajah, L. L., van den Berg, R., Mol, I. M., van den Heuvel, J. K., Koehorst, M., Groen, A. K., Boelen, A., Kalsbeek, A., Romijn, J. A., et al. (2017) · Journal of Endocrinology · doi:10.1530/joe-17-0503 · Cited by 27 · see citing works

Thyroid hormones mediate metabolic rate and oxidative, anti-oxidative balance at different temperatures in Mongolian gerbils (Meriones unguiculatus)

Khakisahneh, S., Zhang, X., Nouri, Z., Hao, S.-Y., Chi, Q., & Wang, D. (2018) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2018.11.016 · Cited by 27 · see citing works

Thyroid Hormone Signaling in Male Mouse Skeletal Muscle Is Largely Independent of D2 in Myocytes

Werneck‐de‐Castro, J. P., Fonseca, T. L., Ignacio, D. L., Fernandes, G. W., Andrade-Feraud, C. M., Lartey, L. J., Ribeiro, M. B., Ribeiro, M. O., Gereben, B., & Bianco, A. C. (2015) · Endocrinology · doi:10.1210/en.2015-1246 · Cited by 26 · see citing works

Efficacy of protocols for induction of chronic hyperthyroidism in male and female mice

Engels, K., Rakov, H., Zwanziger, D., Hönes, G. S., Rehders, M., Brix, K., Köhrle, J., Möller, L. C., & Führer, D. (2016) · Endocrine · doi:10.1007/s12020-016-1020-8 · Cited by 26 · see citing works

Cardiac ischemia/reperfusion injury is inversely affected by thyroid hormones excess or deficiency in male Wistar rats

Seara, F. D. A. C., Maciel, L., Barbosa, R. A. Q., Rodrigues, N. C., da Silveira, A. L. B., Marassi, M. P., Carvalho, A. B., Nascimento, J. H. M., & Olivares, E. L. (2018) · PLoS ONE · doi:10.1371/journal.pone.0190355 · Cited by 26 · see citing works

Type 1 5′-deiodinase activity is inhibited by oxidative stress and restored by alpha-lipoic acid in HepG2 cells

Chen, K., Yan, B., Wang, F., Wen, F., Xing, X., Xue Ming, T. A. N. G., Shi, Y., & Le, G. (2016) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2016.02.119 · Cited by 25 · see citing works

Stem Cells from Healthy and Tendinopathic Human Tendons: Morphology, Collagen and Cytokines Expression and Their Response to T3 Thyroid Hormone

Ciardulli, M. C., Scala, P., Giudice, V., Santoro, A., Selleri, C., Oliva, F., Maffulli, N., & Porta, G. D. (2022) · Cells · doi:10.3390/cells11162545 · Cited by 25 · see citing works

Differences in Mouse Hepatic Thyroid Hormone Transporter Expression with Age and Hyperthyroidism

Engels, K., Rakov, H., Zwanziger, D., Moeller, L. C., Homuth, G., Köhrle, J., Brix, K., & Führer, D. (2015) · European Thyroid Journal · doi:10.1159/000381020 · Cited by 25 · see citing works

Metal coordinated poly-zinc-liothyronine provides stable circulating triiodothyronine levels in hypothyroid rats

Da Conceição, R. R., Fernandes, G. W., Fonseca, T. L., Bocco, B. M. L. C., & Bianco, A. C. (2018) · Thyroid · doi:10.1089/thy.2018.0205 · Cited by 23 · see citing works

Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Regulates the Hypothalamo-Pituitary-Thyroid (HPT) Axis via Type 2 Deiodinase in Male Mice

Egri, P., Fekete, C., Dénes, Á., Reglődi, D., Hashimoto, H., Fulop, B. D., & Gereben, B. (2016) · Endocrinology · doi:10.1210/en.2016-1043 · Cited by 23 · see citing works

The Foxo1-Inducible Transcriptional Repressor Zfp125 Causes Hepatic Steatosis and Hypercholesterolemia

Fernandes, G. W., Bocco, B. M. L. C., Fonseca, T. L., McAninch, E. A., Jo, S., Lartey, L. J., O‐Sullivan, I., Unterman, T. G., Preite, N. Z., Voigt, R. M., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2017.12.053 · Cited by 23 · see citing works

Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – part II: how can key events of relevant adverse outcome pathways be addressed in toxicological assessments?

Marty, S., Beekhuijzen, M. E. W., Charlton, A., Hallmark, N., Hannas, B. R., Jacobi, S., Melching‐Kollmuss, S., Sauer, U. G., Sheets, L. P., Strauss, V., et al. (2021) · Critical Reviews in Toxicology · doi:10.1080/10408444.2021.1910625 · Cited by 23 · see citing works

Associations Between Thyroid and Blood Pressure in Euthyroid Adults: A 9-Year Longitudinal Study

Abdi, H., Gharibzadeh, S., Tasdighi, E., Amouzegar, A., Mehran, L., Tohidi, M., & Azizi, F. (2018) · Hormone and Metabolic Research · doi:10.1055/s-0044-101756 · Cited by 22 · see citing works

Impaired T3 uptake and action in MCT8-deficient cerebral organoids underlie Allan-Herndon-Dudley syndrome

Salas-Lucia, F., Escamilla, S., Bianco, A. C., Dumitrescu, A. M., & Refetoff, S. (2024) · JCI Insight · doi:10.1172/jci.insight.174645 · Cited by 24 · see citing works

Maternal Inheritance of an Inactive Type III Deiodinase Gene Allele Affects Mouse Pancreatic β-Cells and Disrupts Glucose Homeostasis

Medina, M. C., Fonesca, T. L., Molina, J., Fachado, A., Castillo, M., Dong, L., Soares, R., Hernández, A., Caicedo, A., & Bianco, A. C. (2014) · Endocrinology · doi:10.1210/en.2013-1208 · Cited by 21 · see citing works

Minireview: Deciphering Direct and Indirect Influence of Thyroid Hormone With Mouse Genetics

Picou, F., Fauquier, T., Chatonnet, F., Richard, S., & Flamant, F. (2014) · Molecular Endocrinology · doi:10.1210/me.2013-1414 · Cited by 21 · see citing works

Auto-regulation of the thyroid gland beyond classical pathways

Brix, K., Szumska, J., Weber, J., Qatato, M., Venugopalan, V., Al-Hashimi, A., & Rehders, M. (2020) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/a-1080-2969 · Cited by 21 · see citing works

Thyroid redox imbalance in adult Wistar rats that were exposed to nicotine during breastfeeding

Miranda, R. A., de Moura, E. G., Soares, P. N., Peixoto, T. C., Lopes, B. P., de Andrade, C. B. V., OLIVEIRA, E. B. D., Manhães, A. C., de Faria, C. C., Fortunato, R. S., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-72725-w · Cited by 21 · see citing works

Involvement of Nitric Oxide in Iodine Deficiency-Induced Microvascular Remodeling in the Thyroid Gland: Role of Nitric Oxide Synthase 3 and Ryanodine Receptors

Craps, J., Wilvers, C., Joris, V., Jongh, B. D., Vanderstraeten, J., Lobysheva, I. I., Balligand, J., Sonveaux, P., Gilon, P., Many, M., et al. (2014) · Endocrinology · doi:10.1210/en.2014-1729 · Cited by 21 · see citing works

Selpercatinib-Induced Hypothyroidism Through Off-Target Inhibition of Type 2 Iodothyronine Deiodinase

Boucai, L., Salas-Lucia, F., Krishnamoorthy, G. P., Sherman, E. J., Rudin, C. M., Drilon, A. E. D. C., Bianco, A. C., & Fagin, J. A. (2022) · JCO Precision Oncology · doi:10.1200/po.21.00496 · Cited by 21 · see citing works

DBP exposure induces thyroid inflammatory impairment through activating AKT/NF-κB/NLRP3 signaling

Li, L., Xia, Y., Chen, J., Han, X., Hao, L., Li, D., & Liu, Y. (2023) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2023.115385 · Cited by 20 · see citing works

Understanding the Healthy Thyroid State in 2015

F�hrer, D., Brix, K., & Biebermann, H. (2015) · European Thyroid Journal · doi:10.1159/000431318 · Cited by 19 · see citing works

Subacute and low-dose tributyltin exposure disturbs the mammalian hypothalamus-pituitary-thyroid axis in a sex-dependent manner

Rodrigues-Pereira, P., Andrade, M. N., Santos-Silva, A. P., Teixeira, M. P., Soares, P., Graceli, J. B., de Carvalho, D. P., Dias, G. R. M., Ferreira, A. C. F., & Miranda‐Alves, L. (2022) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2022.109279 · Cited by 19 · see citing works

Sustained Pituitary T3 Production Explains the T4-mediated TSH Feedback Mechanism

Batistuzzo, A., Salas-Lucia, F., Gereben, B., Ribeiro, M. O., & Bianco, A. C. (2023) · Endocrinology · doi:10.1210/endocr/bqad155 · Cited by 18 · see citing works

The Impact of a Non-Functional Thyroid Receptor Beta upon Triiodotironine-Induced Cardiac Hypertrophy in Mice

Império, G. E., Ramos, I. P., Santiago, L. A., Pereira, G. F., Almeida, N. A. D. S., Fuziwara, C. S., Pazos-Moura, C. C., Kimura, E. T., Olivares, E. L., & Ortiga-Carvalho, T. M. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000430370 · Cited by 17 · see citing works

A Transgenic Mouse Model for Detection of Tissue-Specific Thyroid Hormone Action

Mohácsik, P., Erdélyi, F., Baranyi, M., Botz, B., Szabó, G., Tóth, M., Haltrich, I., Helyes, Z., Sperlágh, B., Tóth, Z., et al. (2017) · Endocrinology · doi:10.1210/en.2017-00582 · Cited by 18 · see citing works

Exposure to Thyroid-Disrupting Chemicals: A Transatlantic Call for Action

Leung, A. M., Korevaar, T. I. M., Peeters, R. P., Zoeller, R. T., Köhrle, J., Duntas, L. H., Brent, G. A., & DEMENEIX, B. A. (2016) · Thyroid · doi:10.1089/thy.2016.0077 · Cited by 18 · see citing works

Sex Dimorphic Responses of the Hypothalamus–Pituitary–Thyroid Axis to Maternal Separation and Palatable Diet

Jaimes-Hoy, L., Romero, F., Charli, J., & Joseph‐Bravo, P. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00445 · Cited by 18 · see citing works

TAK1-AMPK Pathway in Macrophages Regulates Hypothyroid Atherosclerosis

Yang, Y., Jia, Y., Ning, Y., Wen, W., Qin, Y., Zhang, H., Du, Y., Li, L., Jiao, X., Yang, Y., et al. (2020) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-020-06996-w · Cited by 18 · see citing works

Different Hypothalamic Mechanisms Control Decreased Circulating Thyroid Hormone Levels in Infection and Fasting-Induced Non-Thyroidal Illness Syndrome in Male Thyroid Hormone Action Indicator Mice

Sinkó, R., Mohácsik, P., Kővári, D., Penksza, V., Wittmann, G., Mácsai, L., Fonseca, T. L., Bianco, A. C., Fekete, C., & Gereben, B. (2022) · Thyroid · doi:10.1089/thy.2022.0404 · Cited by 17 · see citing works

Influence of Organotin on Thyroid Morphophysiological Status

Miranda‐Alves, L., & Rio de Janeiro, R. (2015) · JOURNAL OF ENVIRONMENT AND HEALTH SCIENCE · doi:10.15436/2378-6841.15.018 · Cited by 15 · see citing works

Basal Autophagy Deficiency Causes Thyroid Follicular Epithelial Cell Death in Mice

Kurashige, T., Nakajima, Y., Shimamura, M. I., Matsuyama, M. M., Yamada, M., Nakashima, M., & Nagayama, Y. (2019) · Endocrinology · doi:10.1210/en.2019-00312 · Cited by 15 · see citing works

Myocardial Induction of Type 3 Deiodinase in Dilated Cardiomyopathy

Wassner, A. J., Jugo, R. H., Dorfman, D. M., Padera, R. F., Maynard, M. A., Zavacki, A. M., Jay, P. Y., & Huang, S. A. (2017) · Thyroid · doi:10.1089/thy.2016.0570 · Cited by 14 · see citing works

The effects of glyphosate-based herbicide on the hypothalamic-pituitary thyroid axis are tissue-specific and dependent on age exposure

Bender, J. M. D. O., Zenzeluk, J., Bargi‐Souza, P., Szawka, R. E., Romano, M. A., & Romano, R. M. (2023) · Environmental Pollution · doi:10.1016/j.envpol.2023.122216 · Cited by 14 · see citing works

Arsenic-Induced Thyroid Hormonal Alterations and Their Putative Influence on Ovarian Follicles in Balb/c Mice

Nandheeswari, K., Jayapradha, P., Nalla, S. V., Dubey, I., & Kushwaha, S. (2023) · Biological Trace Element Research · doi:10.1007/s12011-023-03988-3 · Cited by 14 · see citing works

Imbalanced testicular metabolism induced by thyroid disorders: New evidences from quantitative proteome

Gomes, S. N., Corrêa, D. E. D. C., de Oliveira, I. M., Bargi‐Souza, P., Cavallin, M. D., Mariano, D. D., Khalil, N. M., Figueiredo, D. L. A., Romano, M. A., de Oliveira, C. A., et al. (2019) · Endocrine · doi:10.1007/s12020-019-01989-8 · Cited by 14 · see citing works

Voluntary Exercise-Induced Activation of Thyroid Axis and Reduction of White Fat Depots Is Attenuated by Chronic Stress in a Sex Dimorphic Pattern in Adult Rats

de, M. A. P.-M., Gutiérrez-Mariscal, M., Salmerón-Jiménez, M. F., Jaimes-Hoy, L., Charli, J., & Joseph‐Bravo, P. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00418 · Cited by 13 · see citing works

Disruption of the thyroid hormone system and patterns of altered thyroid hormones after gestational chemical exposures in rodents – a systematic review

Forner-Piquer, I., Baig, A. H., & Kortenkamp, A. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1323284 · Cited by 14 · see citing works

Increased Thyroid Hormone Action Alleviates Hippocampal Damage by Downregulating Neuronal Type I Interferon Signaling/Necroptosis in Diabetes-Associated Cognitive Dysfunction

Tian, L., Li, X., Zeng, X., Han, Y., Qian, M., Yan, Y., Lin, L., Li, Y., Zhang, J., Liu, Y., et al. (2024) · Thyroid · doi:10.1089/thy.2024.0087 · Cited by 13 · see citing works

Early Developmental Disruption of Type 2 Deiodinase Pathway in Mouse Skeletal Muscle Does Not Impair Muscle Function

Ignacio, D. L., Silvestre, D. H., Anne‐Palmer, E., Bocco, B. M. L. C., Fonseca, T. L., Ribeiro, M. O., Gereben, B., Bianco, A. C., & Werneck‐de‐Castro, J. P. (2016) · Thyroid · doi:10.1089/thy.2016.0392 · Cited by 13 · see citing works

Changes in Hepatic TRβ Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model

Ohba, K., Sinha, R. A., Singh, B. K., Iannucci, L. F., Zhou, J., Kovalik, J., Liao, X.-H., Refetoff, S., Sng, J., Leow, M. K., et al. (2017) · Thyroid · doi:10.1089/thy.2016.0456 · Cited by 13 · see citing works

Retinal S-opsin dominance in Ansell’s mole-rats (Fukomys anselli) is a consequence of naturally low serum thyroxine

Henning, Y., Mladěnková, N., Burda, H., Szafranski, K., & Begall, S. (2018) · Scientific Reports · doi:10.1038/s41598-018-22705-y · Cited by 13 · see citing works

Establishment of an Effective Radioiodide Thyroid Ablation Protocol in Mice

Schmohl, K. A., Müller, A. M., Schwenk, N., Knoop, K., Rijntjes, E., Köhrle, J., Heuer, H., Bartenstein, P., Göke, B., Nelson, P. J., et al. (2015) · European Thyroid Journal · doi:10.1159/000381019 · Cited by 13 · see citing works

Combined Effect of Monieziosis and Hypomicroelementosis on Some Hematological, Biochemical and Hormonal Parameters in Merino Sheep

Abdelhamid, M. (2021) · Pakistan Veterinary Journal · doi:10.29261/pakvetj/2020.068 · Cited by 13 · see citing works

Thyroid-stimulating hormone may participate in insulin resistance by activating toll-like receptor 4 in liver tissues of subclinical hypothyroid rats

Bao, S., Li, F., Duan, L., Li, J., & Jiang, X. (2023) · Molecular Biology Reports · doi:10.1007/s11033-023-08834-2 · Cited by 13 · see citing works

Disruptive Effect of Organotin on Thyroid Gland Function Might Contribute to Hypothyroidism

de Oliveira, M., Rodrigues, B. M., Olímpio, R. M. C., Graceli, J. B., Gonçalves, B. M., Costa, S. M. B., da Silva, T. M., Síbio, M. T. D., Moretto, F. C. F., Mathias, L. S., et al. (2019) · International Journal of Endocrinology · doi:10.1155/2019/7396716 · Cited by 12 · see citing works

Commentary on: “American Thyroid Association Guide to Investigating Thyroid Hormone Economy and Action in Rodent and Cell Models,” Bianco et al.

Brent, G. A. (2013) · Thyroid · doi:10.1089/thy.2013.0679 · Cited by 9 · see citing works

Response to Fitzgerald et al. re: “Thyroid Stimulating Hormone and Thyroid Hormones (Triiodothyronine and Thyroxine): An American Thyroid Association-Commissioned Review of Current Clinical and Laboratory Status”

Andersen, S., & Andersen, S. L. (2024) · Thyroid · doi:10.1089/thy.2024.0049 · Cited by 2 · see citing works

Treatment guidelines for patients with hyperthyroidism and hypothyroidism. Standards of Care Committee, American Thyroid Association

SINGER, P. A. (1995) · JAMA · doi:10.1001/jama.273.10.808 · Cited by 235 · see citing works

Treatment Guidelines for Patients With Hyperthyroidism and Hypothyroidism

Singer, P. A. (1995) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1995.03520340064038 · Cited by 427 · see citing works

Practice guidelines for the detection and management of thyroid dysfunction. A comparative review of the recommendations

Arbelle, J. E., & Porath, A. (1999) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1999.00797.x · Cited by 18 · see citing works