Schroth, Gary P.

Alternative isoform regulation in human tissue transcriptomes

Wang, E. T., Sandberg, R., Luo, S., Khrebtukova, I., Zhang, L., Mayr, C., Kingsmore, S. F., Schroth, G. P., & Burge, C. B. (2008) · Nature

RNA Research and SplicingRNA regulation and disease

Cited by 5,181

Accurate whole human genome sequencing using reversible terminator chemistry

Bentley, D. R., Balasubramanian, S., Swerdlow, H. P., Smith, G. P., Milton, J., Brown, C. G., Hall, K. P., Evers, D. J., Barnes, C. L., Bignell, H. R., et al. (2008) · Nature

Genomics and Phylogenetic StudiesGenomics and Rare Diseases

Cited by 3,684

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

MAQC Consortium, Shi, L., Shi, L., Reid, L. H., Jones, W. D., Shippy, R., Warrington, J. A., Baker, S. C., Collins, P. J., de Longueville, F., et al. (2006) · Nature Biotechnology

Gene expression and cancer classificationMolecular Biology Techniques and Applications

Cited by 2,126

High density DNA methylation array with single CpG site resolution

Bibikova, M., Barnes, B., Tsan, C., Ho, V., Klotzle, B., Le, J. M., Delano, D., Zhang, L., Schroth, G. P., Gunderson, K. L., et al. (2011) · Genomics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 1,727

Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells

Ramsköld, D., Luo, S., Wang, Y.-C., Li, R., Deng, Q., Faridani, O. R., Daniels, G. A., Khrebtukova, I., Loring, J. F., Laurent, L. C., et al. (2012) · Nature Biotechnology

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 1,609

Metagenomic discovery of biomass-degrading genes and genomes from cow rumen

Hess, M., Sczyrba, A., Egan, R., Kim, T.-W., Chokhawala, H., Schroth, G., Luo, S., Clark, D. S., Chen, F., Zhang, T., et al. (2011) · Science

Biofuel production and bioconversionAnaerobic Digestion and Biogas Production

Cited by 1,319

Mammalian microRNAs: experimental evaluation of novel and previously annotated genes

Chiang, H. R., Schoenfeld, L. W., Ruby, J. G., Auyeung, V. C., Spies, N., Baek, D., Johnston, W. K., Russ, C., Luo, S., Babiarz, J. E., et al. (2010) · Genes & Development

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 825

Carrier testing for severe childhood recessive diseases by next-generation sequencing

Bell, C. J., Dinwiddie, D. L., Miller, N. A., Hateley, S. L., Ganusova, E. E., Mudge, J., Langley, R. J., Zhang, L., Lee, C. C., Schilkey, F. D., et al. (2011) · Science Translational Medicine

Genomics and Rare DiseasesPrenatal Screening and Diagnostics

Cited by 706

Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study

Mestdagh, P., Hartmann, N., Baeriswyl, L., Andreasen, D., Bernard, N., Chen, C., Cheo, D., D'Andrade, P., DeMayo, M., Dennis, L., et al. (2014) · Nature Methods

MicroRNA in disease regulationMolecular Biology Techniques and Applications

Cited by 660

High-Resolution Analysis of Parent-of-Origin Allelic Expression in the Mouse Brain

Gregg, C., Zhang, J., Weissbourd, B., Luo, S., Schroth, G. P., Haig, D., & Dulac, C. (2010) · Science

Genetic Syndromes and ImprintingGenomics and Chromatin Dynamics

Cited by 591

Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins

Wang, E. T., Cody, N. A. L., Jog, S., Biancolella, M., Wang, T. T., Treacy, D. J., Luo, S., Schroth, G. P., Housman, D. E., Reddy, S., et al. (2012) · Cell

RNA Research and SplicingMuscle Physiology and Disorders

Cited by 490

Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis

Baranzini, S. E., Mudge, J., van Velkinburgh, J. C., Khankhanian, P., Khrebtukova, I., Miller, N. A., Zhang, L., Farmer, A. D., Bell, C. J., Kim, R. W., et al. (2010) · Nature

Multiple Sclerosis Research StudiesGenetic Associations and Epidemiology

Cited by 476

From single-cell to cell-pool transcriptomes: Stochasticity in gene expression and RNA splicing

Marinov, G. K., Williams, B. A., McCue, K., Schroth, G. P., Gertz, J., Myers, R. M., & Wold, B. J. (2014) · Genome Research

Single-cell and spatial transcriptomicsRNA Research and Splicing

Cited by 468

Studies of the DNA binding properties of histone H4 amino terminus. Thermal denaturation studies reveal that acetylation markedly reduces the binding constant of the H4 “tail” to DNA.

Hong, L., Schroth, G. P., Matthews, H. R., Yau, P., & Bradbury, E. M. (1993) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsDNA and Nucleic Acid Chemistry

Cited by 432

Cohesin-mediated interactions organize chromosomal domain architecture

Sofueva, S., Yaffe, E., Chan, W., Georgopoulou, D., Vietri Rudan, M., Mira‐Bontenbal, H., Pollard, S. M., Schroth, G. P., Tanay, A., & Hadjur, S. (2013) · The EMBO Journal

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 394

Chimeric transcript discovery by paired-end transcriptome sequencing

Maher, C. A., Palanisamy, N., Brenner, J. C., Cao, X., Kalyana-Sundaram, S., Luo, S., Khrebtukova, I., Barrette, T. R., Grasso, C., Yu, J., et al. (2009) · Proceedings of the National Academy of Sciences

Genomics and Phylogenetic StudiesCancer Genomics and Diagnostics

Cited by 339

A highly annotated whole-genome sequence of a Korean individual

Kim, J.-I., Ju, Y. S., Park, H., Kim, S., Lee, S., Yi, J.-H., Mudge, J., Miller, N. A., Hong, D., Bell, C. J., et al. (2009) · Nature

Genomics and Phylogenetic StudiesGenomic variations and chromosomal abnormalities

Cited by 330

Base-Pair Resolution DNA Methylation Sequencing Reveals Profoundly Divergent Epigenetic Landscapes in Acute Myeloid Leukemia

Akalin, A., Garrett-Bakelman, F. E., Kormaksson, M., Busuttil, J., Zhang, L., Khrebtukova, I., Milne, T. A., Huang, Y., Biswas, D., Hess, J. L., et al. (2012) · PLoS Genetics

Epigenetics and DNA MethylationAcute Myeloid Leukemia Research

Cited by 296

Direct measurement of DNA affinity landscapes on a high-throughput sequencing instrument

Nutiu, R., Friedman, R. C., Luo, S., Khrebtukova, I., Silva, D., Li, R., Zhang, L., Schroth, G. P., & Burge, C. B. (2011) · Nature Biotechnology

Genomics and Chromatin DynamicsDiffusion and Search Dynamics

Cited by 194

The RNA Atlas expands the catalog of human non-coding RNAs

Lorenzi, L., Chiu, H.-S., Avila Cobos, F., Gross, S., Volders, P.-J., Cannoodt, R., Nuytens, J., Vanderheyden, K., Anckaert, J., Lefever, S., et al. (2021) · Nature Biotechnology

Cancer-related molecular mechanisms researchRNA Research and Splicing

Cited by 163

The genome of the vervet (Chlorocebus aethiops sabaeus)

Warren, W. C., Jasinska, A. J., García-Pérez, R., Svardal, H., Tomlinson, C., Rocchi, M., Archidiacono, N., Capozzi, O., Minx, P., Montague, M. J., et al. (2015) · Genome Research

Chromosomal and Genetic VariationsGenomics and Phylogenetic Studies

Cited by 123

Dedifferentiation and neuronal repression define familial Alzheimer’s disease

Caldwell, A. B., Liu, Q., Schroth, G. P., Galasko, D. R., Yuan, S. H., Wagner, S. L., & Subramaniam, S. (2020) · Science Advances

Alzheimer's disease research and treatmentsPluripotent Stem Cells Research

Cited by 69

Highly sensitive profiling of CD44+/CD24− breast cancer stem cells by combining global mRNA amplification and next generation sequencing: Evidence for a hyperactive PI3K pathway

Hardt, O., Wild, S., Oerlecke, I., Hofmann, K., Luo, S., Wiencek, Y., Kantelhardt, E., Vess, C., Smith, G. P., Schroth, G. P., et al. (2012) · Cancer Letters

Cancer Cells and MetastasisPI3K/AKT/mTOR signaling in cancer

Cited by 64