Halestrap, Andrew P.

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

OWEN, M. R., DORAN, E., & HALESTRAP, A. P. (2000) · Biochemical Journal

Metabolism, Diabetes, and CancerMitochondrial Function and Pathology

Cited by 2,157

Role of calcium ions in regulation of mammalian intramitochondrial metabolism

McCormack, J. G., Halestrap, A. P., & Denton, R. M. (1990) · Physiological Reviews

Mitochondrial Function and PathologyCalcium signaling and nucleotide metabolism

Cited by 1,398

Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter

Friesema, E. C. H., Ganguly, S., Abdalla, A., Fox, J. E. M., Halestrap, A. P., & Visser, T. J. (2003) · Journal of Biological Chemistry

Thyroid Disorders and TreatmentsDrug Transport and Resistance Mechanisms

Cited by 725

The permeability transition pore complex: another view

Halestrap, A. P., McStay, G. P., & Clarke, S. J. (2002) · Biochimie

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 709

Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation

Friesema, E. C., Grueters, A., Biebermann, H., Krude, H., von Moers, A., Reeser, M., Barrett, T. G., Mancilla, E. E., Svensson, J., Kester, M. H., et al. (2004) · The Lancet

Thyroid Disorders and TreatmentsGenomics and Rare Diseases

Cited by 709

The mitochondrial pyruvate carrier. Kinetics and specificity for substrates and inhibitors

Halestrap, A. P. (1975) · Biochemical Journal

Mitochondrial Function and PathologyBiochemical Acid Research Studies

Cited by 543

The role of mitochondria in protection of the heart by preconditioning

Halestrap, A. P., Clarke, S. J., & Khaliulin, I. (2007) · Biochimica et Biophysica Acta (BBA) - Bioenergetics

Cardiac Ischemia and ReperfusionMitochondrial Function and Pathology

Cited by 390

Sanglifehrin A Acts as a Potent Inhibitor of the Mitochondrial Permeability Transition and Reperfusion Injury of the Heart by Binding to Cyclophilin-D at a Different Site from Cyclosporin A

Clarke, S. J., McStay, G. P., & Halestrap, A. P. (2002) · Journal of Biological Chemistry

Mitochondrial Function and PathologySignaling Pathways in Disease

Cited by 376

Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore

McSTAY, G. P., CLARKE, S. J., & HALESTRAP, A. P. (2002) · Biochemical Journal

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 367

The role of the mitochondrial permeability transition pore in heart disease

Halestrap, A. P., & Pasdois, P. (2009) · Biochimica et Biophysica Acta (BBA) - Bioenergetics

Mitochondrial Function and PathologyCardiac Ischemia and Reperfusion

Cited by 362

Recent progress in elucidating the molecular mechanism of the mitochondrial permeability transition pore

Leung, A. W. C., & Halestrap, A. P. (2008) · Biochimica et Biophysica Acta (BBA) - Bioenergetics

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 323

Recruitment of mitochondrial cyclophilin to the mitochondrial inner membrane under conditions of oxidative stress that enhance the opening of a calcium-sensitive non-specific channel

Connern, C. P., & Halestrap, A. P. (1994) · Biochemical Journal

Mitochondrial Function and PathologySignaling Pathways in Disease

Cited by 246

Energy Metabolism during Apoptosis

Garland, J. M., & Halestrap, A. (1997) · Journal of Biological Chemistry

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 207

A novel postsynaptic density protein: the monocarboxylate transporter MCT2 is co-localized with δ-glutamate receptors in postsynaptic densities of parallel fiber-Purkinje cell synapses

Bergersen, L., Wærhaug, O., Helm, J., Thomas, M., Laake, P., Davies, A. J., Wilson, M. C., Halestrap, A. P., & Ottersen, O. P. (2001) · Experimental Brain Research

Neuroscience and Neuropharmacology ResearchAmino Acid Enzymes and Metabolism

Cited by 155

Determination of the rate of K+ movement through potassium channels in isolated rat heart and liver mitochondria

Bednarczyk, P., Barker, G. D., & Halestrap, A. P. (2008) · Biochimica et Biophysica Acta (BBA) - Bioenergetics

Mitochondrial Function and PathologyIon channel regulation and function

Cited by 54