Moran, John V.

Initial sequencing and analysis of the human genome

International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature

Genomics and Phylogenetic StudiesGenetic Associations and Epidemiology

Cited by 24,216

Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition

Feng, Q., Moran, J. V., Kazazian, H. H., & Boeke, J. D. (1996) · Cell

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 1,139

Hot L1s account for the bulk of retrotransposition in the human population

Brouha, B., Schustak, J., Badge, R. M., Lutz-Prigge, S., Farley, A. H., Moran, J. V., & Kazazian, H. H. (2003) · Proceedings of the National Academy of Sciences

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 1,073

High frequency retrotransposition in cultured mammalian cells

Moran, J. V., Holmes, S. E., Naas, T. P., DeBerardinis, R. J., Boeke, J. D., & Kazazian, H. H. (1996) · Cell

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 1,022

Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition

Muotri, A. R., Chu, V. T., Marchetto, M. C. N., Deng, W., Moran, J. V., & Gage, F. H. (2005) · Nature

Chromosomal and Genetic VariationsNeurogenesis and neuroplasticity mechanisms

Cited by 942

L1 retrotransposition in human neural progenitor cells

Coufal, N. G., Garcia-Perez, J. L., Peng, G. E., Yeo, G. W., Mu, Y., Lovci, M. T., Morell, M., O’Shea, K. S., Moran, J. V., & Gage, F. H. (2009) · Nature

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 814

LINE-1 Retrotransposition Activity in Human Genomes

Beck, C. R., Collier, P., Macfarlane, C., Malig, M., Kidd, J. M., Eichler, E. E., Badge, R. M., & Moran, J. V. (2010) · Cell

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 632

Dynamic interactions between transposable elements and their hosts

Levin, H. L., & Moran, J. V. (2011) · Nature Reviews Genetics

Chromosomal and Genetic VariationsGenomics and Chromatin Dynamics

Cited by 621

LINE-1 elements in structural variation and disease

Beck, C. R., Garcia-Perez, J. L., Badge, R. M., & Moran, J. V. (2011) · Annual Review of Genomics and Human Genetics

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 615

Mobile elements and mammalian genome evolution

Deininger, P. L., Moran, J. V., Batzer, M. A., & Kazazian, H. H. (2003) · Current Opinion in Genetics & Development

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 479

Genomic Deletions Created upon LINE-1 Retrotransposition

Gilbert, N., Lutz-Prigge, S., & Moran, J. V. (2002) · Cell

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 474

Mobile DNA in Health and Disease

Kazazian, H. H., & Moran, J. V. (2017) · New England Journal of Medicine

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 445

Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network

McConnell, M. J., Moran, J. V., Abyzov, A., Akbarian, S., Bae, T., Cortes-Ciriano, I., Erwin, J. A., Fasching, L., Flasch, D. A., Freed, D., et al. (2017) · Science

Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders

Cited by 262

Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells

Coufal, N. G., Garcia-Perez, J. L., Peng, G. E., Marchetto, M. C. N., Muotri, A. R., Mu, Y., Carson, C. T., Macia, A., Moran, J. V., & Gage, F. H. (2011) · Proceedings of the National Academy of Sciences

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 229

Genome-wide de novo L1 Retrotransposition Connects Endonuclease Activity with Replication

Flasch, D. A., Macia, Á., Sánchez, L., Ljungman, M., Heras, S. R., García-Pérez, J. L., Wilson, T. E., & Moran, J. V. (2019) · Cell

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 127