Becker, Christine

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

Masters, S. L., Dunne, A., Subramanian, S. L., Hull, R. L., Tannahill, G. M., Sharp, F. A., Becker, C., Franchi, L., Yoshihara, E., Chen, Z., et al. (2010) · Nature Immunology

Inflammasome and immune disordersPancreatic function and diabetes

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CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

Sheedy, F. J., Grebe, A., Rayner, K. J., Kalantari, P., Ramkhelawon, B., Carpenter, S. B., Becker, C. E., Ediriweera, H. N., Mullick, A. E., Golenbock, D. T., et al. (2013) · Nature Immunology

Inflammasome and immune disordersAtherosclerosis and Cardiovascular Diseases

Cited by 935

TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria

Rathinam, V. A. K., Vanaja, S. K., Waggoner, L., Sokolovska, A., Becker, C., Stuart, L. M., Leong, J. M., & Fitzgerald, K. A. (2012) · Cell

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 729

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

Lassen, K. G., Kuballa, P., Conway, K. L., Patel, K. K., Becker, C. E., Peloquin, J. M., Villablanca, E. J., Norman, J. M., Liu, T.-C., Heath, R. J., et al. (2014) · Proceedings of the National Academy of Sciences

Autophagy in Disease and TherapyInflammatory Bowel Disease

Cited by 373

Dectin-1–Dependent LC3 Recruitment to Phagosomes Enhances Fungicidal Activity in Macrophages

Tam, J. M., Mansour, M. K., Khan, N. S., Seward, M., Puranam, S., Tanne, A., Sokolovska, A., Becker, C. E., Acharya, M., Baird, M. A., et al. (2014) · The Journal of Infectious Diseases

Autophagy in Disease and TherapyAntifungal resistance and susceptibility

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Dectin-1 Activation Controls Maturation of β-1,3-Glucan-containing Phagosomes

Mansour, M. K., Tam, J. M., Khan, N. S., Seward, M., Davids, P. J., Puranam, S., Sokolovska, A., Sykes, D. B., Dagher, Z., Becker, C., et al. (2013) · Journal of Biological Chemistry

Immune Response and InflammationPhagocytosis and Immune Regulation

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