Andersen, Jan Terje

Unraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based Therapeutics

Sand, K. M. K., Bern, M., Nilsen, J., Noordzij, H. T., Sandlie, I., & Andersen, J. T. (2015) · Frontiers in Immunology

Monoclonal and Polyclonal Antibodies ResearchProtein Interaction Studies and Fluorescence Analysis

Cited by 304

Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential

Stapleton, N. M., Andersen, J. T., Stemerding, A. M., Bjarnarson, S. P., Verheul, R. C., Gerritsen, J., Zhao, Y., Kleijer, M., Sandlie, I., de Haas, M., et al. (2011) · Nature Communications

Monoclonal and Polyclonal Antibodies ResearchT-cell and B-cell Immunology

Cited by 286

Extending Serum Half-life of Albumin by Engineering Neonatal Fc Receptor (FcRn) Binding

Andersen, J. T., Dalhus, B., Viuff, D., Ravn, B. T., Gunnarsen, K. S., Plumridge, A., Bunting, K., Antunes, F., Williamson, R., Athwal, S., et al. (2014) · Journal of Biological Chemistry

Monoclonal and Polyclonal Antibodies ResearchProtein Interaction Studies and Fluorescence Analysis

Cited by 167

A human endothelial cell-based recycling assay for screening of FcRn targeted molecules

Grevys, A., Nilsen, J., Sand, K. M. K., Daba, M. B., Øynebråten, I., Bern, M., McAdam, M. B., Foss, S., Schlothauer, T., Michaelsen, T. E., et al. (2018) · Nature Communications

Monoclonal and Polyclonal Antibodies ResearchDrug Transport and Resistance Mechanisms

Cited by 98

In silico proof of principle of machine learning-based antibody design at unconstrained scale

Akbar, R., Robert, P. A., Weber, C. R., Widrich, M., Frank, R., Pavlović, M., Scheffer, L., Chernigovskaya, M., Snapkov, I., Slabodkin, A., et al. (2022) · mAbs

Monoclonal and Polyclonal Antibodies Researchvaccines and immunoinformatics approaches

Cited by 94

Polymeric human Fc-fusion proteins with modified effector functions

Mekhaiel, D. N. A., Czajkowsky, D. M., Andersen, J. T., Shi, J., El-Faham, M., Doenhoff, M., McIntosh, R. S., Sandlie, I., He, J., Hu, J., et al. (2011) · Scientific Reports

Monoclonal and Polyclonal Antibodies ResearchProtein purification and stability

Cited by 85

Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life

Grevys, A., Frick, R., Mester, S., Flem-Karlsen, K., Nilsen, J., Foss, S., Sand, K. M. K., Emrich, T., Fischer, J. A. A., Greiff, V., et al. (2022) · iScience

Monoclonal and Polyclonal Antibodies ResearchProtein purification and stability

Cited by 51

A new method for pharmaceutical compounding and storage of anti-VEGF biologics for intravitreal use in silicone oil-free prefilled plastic syringes

Lode, H. E., Gjølberg, T. T., Foss, S., Sivertsen, M. S., Brustugun, J., Andersson, Y., Jørstad, Ø. K., Moe, M. C., & Andersen, J. T. (2019) · Scientific Reports

Retinal Diseases and TreatmentsAdvanced Drug Delivery Systems

Cited by 40

Developing the IVIG biomimetic, Hexa-Fc, for drug and vaccine applications

Czajkowsky, D. M., Andersen, J. T., Fuchs, A., Wilson, T. J., Mekhaiel, D., Colonna, M., He, J., Shao, Z., Mitchell, D. A., Wu, G., et al. (2015) · Scientific Reports

Monoclonal and Polyclonal Antibodies ResearchProtein purification and stability

Cited by 38

On the Perplexingly Low Rate of Transport of IgG2 across the Human Placenta

Einarsdottir, H. K., Stapleton, N. M., Scherjon, S., Andersen, J. T., Rispens, T., van der Schoot, C. E., & Vidarsson, G. (2014) · PLoS ONE

Monoclonal and Polyclonal Antibodies ResearchImmunodeficiency and Autoimmune Disorders

Cited by 38

Biophysical cartography of the native and human-engineered antibody landscapes quantifies the plasticity of antibody developability

Bashour, H., Smorodina, E., Pariset, M., Zhong, J., Akbar, R., Chernigovskaya, M., Lê Quý, K., Snapkow, I., Rawat, P., Krawczyk, K., et al. (2024) · Communications Biology

Monoclonal and Polyclonal Antibodies Researchvaccines and immunoinformatics approaches

Cited by 32

Biophysical cartography of the native and human-engineered antibody landscapes quantifies the plasticity of antibody developability

Bashour, H., Smorodina, E., Pariset, M., Zhong, J., Akbar, R., Chernigovskaya, M., Quý, K. L., Snapkov, I., Rawat, P., Krawczyk, K., et al. (2023) · Communications Biology

Monoclonal and Polyclonal Antibodies Researchvaccines and immunoinformatics approaches

Cited by 32

Targeting the Neonatal Fc Receptor in Autoimmune Diseases: Pipeline and Progress

Gjølberg, T. T., Mester, S., Calamera, G., Telstad, J. S., Sandlie, I., & Andersen, J. T. (2025) · BioDrugs

Monoclonal and Polyclonal Antibodies ResearchSystemic Lupus Erythematosus Research

Cited by 20

Phage display assisted discovery of a pH ‐dependent anti‐α‐cobratoxin antibody from a natural variable domain library

Tulika, T., Pedersen, R. W., Rimbault, C., Ahmadi, S., Rivera‐de‐Torre, E., Fernández‐Quintero, M. L., Loeffler, J. R., Bohn, M., Ljungars, A., Ledsgaard, L., et al. (2023) · Protein Science

Monoclonal and Polyclonal Antibodies ResearchVenomous Animal Envenomation and Studies

Cited by 11