Lachmann, Alexander

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

Kuleshov, M. V., Jones, M. R., Rouillard, A. D., Fernandez, N. F., Duan, Q., Wang, Z., Koplev, S., Jenkins, S. L., Jagodnik, K. M., Lachmann, A., et al. (2016) · Nucleic Acids Research

Bioinformatics and Genomic NetworksGenomics and Phylogenetic Studies

Cited by 10,799

Gene set knowledge discovery with enrichr

Xie, Z., Bailey, A., Kuleshov, M. V., Clarke, D. J. B., Evangelista, J. E., Jenkins, S. L., Lachmann, A., Wojciechowicz, M. L., Kropiwnicki, E., Jagodnik, K. M., et al. (2021) · Current Protocols

Bioinformatics and Genomic NetworksGenomics and Phylogenetic Studies

Cited by 3,451

ChEA3: transcription factor enrichment analysis by orthogonal omics integration

Keenan, A. B., Torre, D., Lachmann, A., Leong, A. K., Wojciechowicz, M. L., Utti, V., Jagodnik, K. M., Kropiwnicki, E., Wang, Z., & Ma’ayan, A. (2019) · Nucleic Acids Research

Bioinformatics and Genomic NetworksGenomics and Chromatin Dynamics

Cited by 1,136

Functional characterization of somatic mutations in cancer using network-based inference of protein activity

Alvarez, M. J., Shen, Y., Giorgi, F. M., Lachmann, A., Ding, B. B., Ye, B. H., & Califano, A. (2016) · Nature Genetics

Bioinformatics and Genomic NetworksCancer Genomics and Diagnostics

Cited by 966

Massive mining of publicly available RNA-seq data from human and mouse

Lachmann, A., Torre, D., Keenan, A. B., Jagodnik, K. M., Lee, H. J., Wang, L., Silverstein, M. C., & Ma’ayan, A. (2018) · Nature Communications

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 701

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

Keenan, A. B., Jenkins, S. L., Jagodnik, K. M., Koplev, S., He, E., Torre, D., Wang, Z., Dohlman, A. B., Silverstein, M. C., Lachmann, A., et al. (2018) · Cell Systems

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 423

Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration

von Schimmelmann, M., Feinberg, P. A., Sullivan, J. M., Ku, S. M., Badimon, A., Duff, M. K., Wang, Z., Lachmann, A., Dewell, S., Ma'ayan, A., et al. (2016) · Nature Neuroscience

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 225

L1000FWD: fireworks visualization of drug-induced transcriptomic signatures

Wang, Z., Lachmann, A., Keenan, A. B., & Ma’ayan, A. (2018) · Bioinformatics

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 195

LINCS Data Portal 2.0: next generation access point for perturbation-response signatures

Stathias, V., Turner, J., Koleti, A., Vidovic, D., Cooper, D., Fazel-Najafabadi, M., Pilarczyk, M., Terryn, R., Chung, C., Umeano, A., et al. (2020) · Nucleic Acids Research

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

Cited by 161

Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects

Edwards, J. J., Rouillard, A. D., Fernandez, N. F., Wang, Z., Lachmann, A., Shankaran, S. S., Bisgrove, B. W., Demarest, B., Turan, N., Srivastava, D., et al. (2020) · JACC: Basic to Translational Science

Congenital heart defects researchCardiomyopathy and Myosin Studies

Cited by 27