Padmanabhan, Sandosh

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Program, T. M. V., Evangelou, E., Warren, H. R., Mosen-Ansorena, D., Mifsud, B., Pazoki, R., Gao, H., Ntritsos, G., Dimou, N., Cabrera, C. P., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 1,381

Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

Williams, B., MacDonald, T. M., Morant, S., Webb, D. J., Sever, P., McInnes, G., Ford, I., Cruickshank, J. K., Caulfield, M. J., Salsbury, J., et al. (2015) · The Lancet

Blood Pressure and Hypertension StudiesHormonal Regulation and Hypertension

Cited by 1,308

Mendelian randomization of blood lipids for coronary heart disease

Holmes, M. V., Asselbergs, F. W., Palmer, T. M., Drenos, F., Lanktree, M. B., Nelson, C. P., Dale, C. E., Padmanabhan, S., Finan, C., Swerdlow, D. I., et al. (2015) · European Heart Journal

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 748

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

Holmes, M. V., Dale, C. E., Zuccolo, L., Silverwood, R. J., Guo, Y., Ye, Z., Prieto-Merino, D., Dehghan, A., Trompet, S., Wong, A., et al. (2014) · BMJ

Alcohol Consumption and Health EffectsGenetic Associations and Epidemiology

Cited by 669

Rare and low-frequency coding variants alter human adult height

Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., et al. (2017) · Nature

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 610

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

Study, T. L. C., Day, F. R., The InterAct Consortium, kConFab/AOCS Investigators, Endometrial Cancer Association Consortium, Ovarian Cancer Association Consortium, PRACTICAL consortium, Thompson, D. J., Helgason, H., Chasman, D. I., et al. (2017) · Nature Genetics

Hypothalamic control of reproductive hormonesGenetic Associations and Epidemiology

Cited by 587

Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting

Natarajan, P., Young, R., Stitziel, N. O., Padmanabhan, S., Baber, U., Mehran, R., Sartori, S., Fuster, V., Reilly, D. F., Butterworth, A., et al. (2017) · Circulation

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 570

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)

Clarke, T.-K., Adams, M. J., Davies, G., Howard, D. M., Hall, L. S., Padmanabhan, S., Murray, A. D., Smith, B. H., Campbell, A., Hayward, C., et al. (2017) · Molecular Psychiatry

Genetic Associations and EpidemiologyAlcohol Consumption and Health Effects

Cited by 440

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

The PRACTICAL Consortium, Day, F. R., kConFab Investigators, AOCS Investigators, Scotland, G., EPIC-InterAct Consortium, Study, L. C., Ruth, K. S., Thompson, D. J., Lunetta, K. L., et al. (2015) · Nature Genetics

Genetic Associations and EpidemiologyBRCA gene mutations in cancer

Cited by 402

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

Schmidt, A. F., Swerdlow, D. I., Holmes, M. V., Patel, R. S., Fairhurst-Hunter, Z., Lyall, D. M., Hartwig, F. P., Horta, B. L., Hyppönen, E., Power, C., et al. (2017) · The Lancet Diabetes & Endocrinology

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 380

Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies

Williams, B., MacDonald, T. M., Morant, S. V., Webb, D. J., Sever, P., McInnes, G. T., Ford, I., Cruickshank, J. K., Caulfield, M. J., Padmanabhan, S., et al. (2018) · The Lancet Diabetes & Endocrinology

Hormonal Regulation and HypertensionBlood Pressure and Hypertension Studies

Cited by 347

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

CHARGE-Heart Failure Consortium, Surendran, P., EchoGen Consortium, METASTROKE Consortium, GIANT Consortium, EPIC-InterAct Consortium, Study, L. C., Wellcome Trust Case Control Consortium, Understanding Society Scientific Group, EPIC-CVD Consortium, et al. (2016) · Nature Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 312

Obesity paradox in a cohort of 4880 consecutive patients undergoing percutaneous coronary intervention

Hastie, C. E., Padmanabhan, S., Slack, R., Pell, A. C. H., Oldroyd, K. G., Flapan, A. D., Jennings, K. P., Irving, J., Eteiba, H., Dominiczak, A. F., et al. (2010) · European Heart Journal

Coronary Interventions and DiagnosticsCardiovascular Disease and Adiposity

Cited by 234

Endovascular Ultrasound Renal Denervation to Treat Hypertension: The RADIANCE II Randomized Clinical Trial

Azizi, M., Saxena, M., Wang, Y., Jenkins, J. S., Devireddy, C., Rader, F., Fisher, N. D. L., Schmieder, R. E., Mahfoud, F., Lindsey, J., et al. (2023) · JAMA

Blood Pressure and Hypertension StudiesRenal and Vascular Pathologies

Cited by 199

Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population

Clarke, T.-K., Lupton, M. K., Fernandez-Pujals, A. M., Starr, J., Davies, G., Cox, S., Pattie, A., Liewald, D. C., Hall, L. S., MacIntyre, D. J., et al. (2016) · Molecular Psychiatry

Autism Spectrum Disorder ResearchGenetic Associations and Epidemiology

Cited by 179

No evidence of a common DNA variant profile specific to world class endurance athletes.

Rankinen, T., Fuku, N., Wolfarth, B., Wang, G., Sarzynski, M. A., Alexeev, D. G., Ahmetov, I. I., Boulay, M. R., Cieszczyk, P., Eynon, N., et al. (2016) · PLOS ONE

Genetics and Physical PerformanceGenetic Associations and Epidemiology

Cited by 171

Allopurinol and Cardiovascular Outcomes in Adults With Hypertension

MacIsaac, R. L., Salatzki, J., Higgins, P., Walters, M. R., Padmanabhan, S., Dominiczak, A. F., Touyz, R. M., & Dawson, J. (2016) · Hypertension

Gout, Hyperuricemia, Uric AcidBlood Pressure and Hypertension Studies

Cited by 124

Genetic variation at the SLC23A1 locus is associated with circulating concentrations of l-ascorbic acid (vitamin C): evidence from 5 independent studies with >15,000 participants

Timpson, N. J., Forouhi, N. G., Brion, M.-J., Harbord, R. M., Cook, D. G., Johnson, P., McConnachie, A., Morris, R. W., Rodriguez, S., Luan, J., et al. (2010) · The American Journal of Clinical Nutrition

Genetic Associations and EpidemiologyVitamin C and Antioxidants Research

Cited by 107

Genetic comorbidity between major depression and cardio‐metabolic traits, stratified by age at onset of major depression

Hagenaars, S. P., Coleman, J. R. I., Choi, S. W., Gaspar, H., Adams, M. J., Howard, D. M., Hodgson, K., Traylor, M., Air, T. M., Andlauer, T. F. M., et al. (2020) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 61

Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

Young, W. J., Lahrouchi, N., Isaacs, A., Duong, T., Foco, L., Ahmed, F., Brody, J. A., Salman, R., Noordam, R., Benjamins, J.-W., et al. (2022) · Nature Communications

Cardiac electrophysiology and arrhythmiasGenetic Associations and Epidemiology

Cited by 49

Risk of neuropsychiatric adverse effects of lipid-lowering drugs: a mendelian randomization study

Alghamdi, J., Matou-Nasri, S., Alghamdi, F., Alghamdi, S., Alfadhel, M., & Padmanabhan, S. (2018) · International Journal of Neuropsychopharmacology

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 44

Machine learning integration of multimodal data identifies key features of blood pressure regulation

Louca, P., Tran, T. Q. B., Toit, C. D., Christofidou, P., Spector, T. D., Mangino, M., Suhre, K., Padmanabhan, S., & Menni, C. (2022) · EBioMedicine

Blood Pressure and Hypertension StudiesSodium Intake and Health

Cited by 37

Acetaminophen Use and Risk of Myocardial Infarction and Stroke in a Hypertensive Cohort

Fulton, R. L., Walters, M. R., Morton, R., Touyz, R. M., Dominiczak, A. F., Morrison, D. S., Padmanabhan, S., Meredith, P. A., McInnes, G. T., & Dawson, J. (2015) · Hypertension

Inflammatory mediators and NSAID effectsBlood Pressure and Hypertension Studies

Cited by 35

Acetaminophen use and change in blood pressure in a hypertensive population

Dawson, J., Fulton, R., McInnes, G. T., Morton, R., Morrison, D., Padmanabhan, S., Hewitt, J., Meredith, P., Muir, S., Dominiczak, A. F., et al. (2013) · Journal of Hypertension

Blood Pressure and Hypertension StudiesInflammatory mediators and NSAID effects

Cited by 27