Gakh, Oleksandr

Mitochondrial iron detoxification is a primary function of frataxin that limits oxidative damage and preserves cell longevity

Gakh, O., Park, S., Liu, G., Macomber, L., Imlay, J. A., Ferreira, G. C., & Isaya, G. (2006) · Human Molecular Genetics

Mitochondrial Function and PathologyGenetic Neurodegenerative Diseases

Cited by 184

The Ferroxidase Activity of Yeast Frataxin

Park, S., Gakh, O., Mooney, S. M., & Isaya, G. (2002) · Journal of Biological Chemistry

Metal-Catalyzed Oxygenation MechanismsMetalloenzymes and iron-sulfur proteins

Cited by 88

The Structures of Frataxin Oligomers Reveal the Mechanism for the Delivery and Detoxification of Iron

Karlberg, T., Schagerlöf, U., Gakh, O., Park, S., Ryde, U., Lindahl, M., Leath, K., Garman, E., Isaya, G., & Al-Karadaghi, S. (2006) · Structure

Enzyme Structure and FunctionNeurological diseases and metabolism

Cited by 85

Infrared spectral profiling of demyelinating activity in multiple sclerosis brain tissue

Gakh, O., Wilkins, J. M., Guo, Y., Popescu, B. F., Weigand, S. D., Kalinowska-Lyszczarz, A., & Lucchinetti, C. F. (2024) · Acta Neuropathologica Communications

Spectroscopy Techniques in Biomedical and Chemical ResearchMultiple Sclerosis Research Studies

Cited by 4