Hockenbery, David

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

Hockenbery, D., Nuñez, G., Milliman, C., Schreiber, R. D., & Korsmeyer, S. J. (1990) · Nature

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 3,720

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

Hockenbery, D. M., Zutter, M., Hickey, W., Nahm, M., & Korsmeyer, S. J. (1991) · Proceedings of the National Academy of Sciences

Cell death mechanisms and regulationT-cell and B-cell Immunology

Cited by 1,252

Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.

Nuñez, G., London, L., Hockenbery, D., Alexander, M., McKearn, J. P., & Korsmeyer, S. J. (1990) · The Journal of Immunology

Cell death mechanisms and regulationLymphoma Diagnosis and Treatment

Cited by 899

Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3

Tzung, S.-P., Kim, K. M., Basañez, G., Giedt, C. D., Simon, J., Zimmerberg, J., Zhang, K. Y. J., & Hockenbery, D. M. (2001) · Nature Cell Biology

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 452

Identification of genes with abnormal expression changes in acute myeloid leukemia

Stirewalt, D. L., Meshinchi, S., Kopecky, K. J., Fan, W., Pogosova‐Agadjanyan, E. L., Engel, J. H., Cronk, M. R., Dorcy, K. S., McQuary, A. R., Hockenbery, D., et al. (2008) · Genes, Chromosomes and Cancer

Acute Myeloid Leukemia ResearchGene expression and cancer classification

Cited by 191

Hsp90 Inhibition Decreases Mitochondrial Protein Turnover

Margineantu, D. H., Emerson, C. B., Diaz, D., & Hockenbery, D. M. (2007) · PLoS ONE

Heat shock proteins researchMitochondrial Function and Pathology

Cited by 147

A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells

Procko, E., Berguig, G. Y., Shen, B. W., Song, Y., Frayo, S., Convertine, A. J., Margineantu, D., Booth, G., Correia, B. E., Cheng, Y., et al. (2014) · Cell

Cell death mechanisms and regulationChemical Synthesis and Analysis

Cited by 127

Enzyme-cleavable polymeric micelles for the intracellular delivery of proapoptotic peptides

Kern, H. B., Srinivasan, S., Convertine, A. J., Hockenbery, D., Press, O. W., & Stayton, P. S. (2017) · Molecular Pharmaceutics

Nanoparticle-Based Drug DeliveryRNA Interference and Gene Delivery

Cited by 63

Warburg and Crabtree Effects in Premalignant Barrett's Esophagus Cell Lines with Active Mitochondria

Suchorolski, M. T., Paulson, T. G., Sanchez, C. A., Hockenbery, D., & Reid, B. J. (2013) · PLoS ONE

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 40