Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

Apoptosis in the Pathogenesis and Treatment of Disease

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Cell Death

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Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3

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CD28/B7 SYSTEM OF T CELL COSTIMULATION

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

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The Role of Mitochondria in Apoptosis

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Apoptosis in Myocytes in End-Stage Heart Failure

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BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

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Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity

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Free Radical Pathways in CNS Injury

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Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies

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Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators

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Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants

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The diagnosis and medical management of advanced neuroendocrine tumors.

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Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFNγ receptors

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Human Effector and Memory CD8+ T Cell Responses to Smallpox and Yellow Fever Vaccines

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Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

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Bcl-xL Prevents Cell Death following Growth Factor Withdrawal by Facilitating Mitochondrial ATP/ADP Exchange

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In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability

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Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3

Tzung, S.-P., Kim, K. M., Basañez, G., Giedt, C. D., Simon, J., Zimmerberg, J., Zhang, K. Y. J., & Hockenbery, D. M. (2001) · Nature Cell Biology · doi:10.1038/35055095 · Cited by 452 · see citing works

Integrated genomic characterization of endometrial carcinoma

The Cancer Genome Atlas Research Network, & Levine, D. A. (2013) · Nature · doi:10.1038/nature12113 · Cited by 5,784 · see citing works

Inhibition of Carnitine Palmitoyltransferase I Augments Sphingolipid Synthesis and Palmitate-induced Apoptosis

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Mitochondria—Judges and Executioners of Cell Death Sentences

Bhola, P. D., & Letai, A. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.02.019 · Cited by 326 · see citing works

Apoptosis of Retinal Ganglion Cells in Glaucoma

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Human complex I deficiency: Clinical spectrum and involvement of oxygen free radicals in the pathogenicity of the defect

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Energy Metabolism during Apoptosis

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Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy

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Pharmacogenetic analysis of lithium-induced delayed aging in Caenorhabditis elegans

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Spatial Distribution of Bax and Bcl-2 in Osteocytes After Bone Fatigue: Complementary Roles in Bone Remodeling Regulation?

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BAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial pore

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Programmed cell death and the control of cell survival

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Apoptosis in Focal Cerebral Ischemia

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The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein–protein interactions with Bak

Cao, X., Yap, J. L., Newell-Rogers, M. K., Peddaboina, C., Jiang, W., Papaconstantinou, H. T., Jupitor, D., Rai, A., Jung, K.-Y., Tubin, R. P., et al. (2013) · Molecular Cancer · doi:10.1186/1476-4598-12-42 · Cited by 87 · see citing works

Development of the human adrenal zona reticularis: morphometric and immunohistochemical studies from birth to adolescence

Hui, X.-G., Akahira, J.-I., Suzuki, T., Nio, M., Nakamura, Y., Suzuki, H., Rainey, W. E., & Sasano, H. (2009) · Journal of Endocrinology · doi:10.1677/joe-09-0127 · Cited by 83 · see citing works

Small molecule modulators of protein-protein interactions: selected case studies

Aeluri, M., Chamakuri, S., Dasari, B., Guduru, S. K. R., Jimmidi, R., Jogula, S., & Arya, P. (2014) · Chemical Reviews · doi:10.1021/cr4004049 · Cited by 79 · see citing works

Diminished apoptotic priming and ATM signalling confer a survival advantage onto aged haematopoietic stem cells in response to DNA damage

Gutierrez-Martinez, P., Hogdal, L., Nagai, M., Kruta, M., Singh, R., Sarosiek, K., Nussenzweig, A., Beerman, I., Letai, A., & Rossi, D. J. (2018) · Nature Cell Biology · doi:10.1038/s41556-018-0054-y · Cited by 60 · see citing works

Induction of apoptosis of gastric cancer cells SGC7901 in vitro by a cell-free fraction of Tibetan kefir

Gao, J., Gu, F., Ruan, H., Chen, Q., He, J., & He, G. (2013) · International Dairy Journal · doi:10.1016/j.idairyj.2012.11.011 · Cited by 54 · see citing works

Cytochrome <i>c</i>, released from cerebellar granule cells undergoing apoptosis or excytotoxic death, can generate protonmotive force and drive ATP synthesis in isolated mitochondria

Atlante, A., De Bari, L., Bobba, A., Marra, E., Calissano, P., & Passarella, S. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01863.x · Cited by 45 · see citing works

Pyridoxal isonicotinoyl hydrazone analogs induce apoptosis in hematopoietic cells due to their iron-chelating properties

Buss, J. L., Neuzil, J., Gellert, N., Weber, C., & Ponka, P. (2003) · Biochemical Pharmacology · doi:10.1016/s0006-2952(02)01512-5 · Cited by 42 · see citing works

Regulation of neutrophil apoptosis

Edwards, S. W., Moulding, D. A., Derouet, M., & Moots, R. J. (2003) · Chemical Immunology and Allergy · doi:10.1159/000071562 · Cited by 41 · see citing works

RTG1- and RTG2-dependent retrograde signaling controls mitochondrial activity and stress resistance in Saccharomyces cerevisiae

Torelli, N. Q., Ferreira-Júnior, J. R., Kowaltowski, A. J., & da Cunha, F. M. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.12.025 · Cited by 37 · see citing works

The effects of ulipristal on Bax/Bcl-2, cytochrome c, Ki-67 and cyclooxygenase-2 expression in a rat model with surgically induced endometriosis

Huniadi, C. A., Pop, O. L., Antal, T. A., & Stamatian, F. (2013) · European Journal of Obstetrics &amp; Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2013.03.022 · Cited by 35 · see citing works

Apoptosis in primary lymphoid organs with aging

Sainz, R. M., Mayo, J. C., Reiter, R. J., Tan, D. X., & Rodriguez, C. (2003) · Microscopy Research and Technique · doi:10.1002/jemt.10414 · Cited by 32 · see citing works

SLE serum induces classical caspase-dependent apoptosis independent of death receptors

Bengtsson, A. A., Gullstrand, B., Truedsson, L., & Sturfelt, G. (2008) · Clinical Immunology · doi:10.1016/j.clim.2007.10.003 · Cited by 29 · see citing works

Combination of carboplatin and intermittent normobaric hyperoxia synergistically suppresses benzo[a]pyrene-induced lung cancer

Lee, H. Y., Kim, I. K., Lee, H. I., Lee, H. Y., Kang, H. S., Yeo, C. D., Kang, H. H., Moon, H. S., & Lee, S. H. (2018) · The Korean Journal of Internal Medicine · doi:10.3904/kjim.2016.334 · Cited by 19 · see citing works