Rouault, Tracey A.

Subcellular compartmentalization of human Nfu, an iron-sulfur cluster scaffold protein, and its ability to assemble a [4Fe-4S] cluster

Tong, W.-H., Jameson, G. N. L., Huynh, B. H., & Rouault, T. A. (2003) · Proceedings of the National Academy of Sciences

Metalloenzymes and iron-sulfur proteinsEnzyme Structure and Function

Cited by 194

Association of Pulmonary Tuberculosis with Increased Dietary Iron

Gangaidzo, I. T., Moyo, V. M., Mvundura, E., Aggrey, G., Murphree, N. L., Khumalo, H., Saungweme, T., Kasvosve, I., Gomo, Z. A. R., Rouault, T., et al. (2001) · The Journal of Infectious Diseases

Tuberculosis Research and EpidemiologyIron Metabolism and Disorders

Cited by 191

Deletion of Iron Regulatory Protein 1 Causes Polycythemia and Pulmonary Hypertension in Mice through Translational Derepression of HIF2α

Ghosh, M. C., Zhang, D.-L., Jeong, S. Y., Kovtunovych, G., Ollivierre-Wilson, H., Noguchi, A., Tu, T., Senecal, T., Robinson, G., Crooks, D. R., et al. (2013) · Cell Metabolism

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 183

Identification of the ubiquitin–protein ligase that recognizes oxidized IRP2

Yamanaka, K., Ishikawa, H., Megumi, Y., Tokunaga, F., Kanie, M., Rouault, T. A., Morishima, I., Minato, N., Ishimori, K., & Iwai, K. (2003) · Nature Cell Biology

Ubiquitin and proteasome pathwaysIron Metabolism and Disorders

Cited by 181

Erythrocytic ferroportin reduces intracellular iron accumulation, hemolysis, and malaria risk

Zhang, D.-L., Wu, J., Shah, B. N., Greutélaers, K. C., Ghosh, M. C., Ollivierre, H., Su, X.-Z., Thuma, P. E., Bedu-Addo, G., Mockenhaupt, F. P., et al. (2018) · Science

Iron Metabolism and DisordersMalaria Research and Control

Cited by 150

Identification of a conserved and functional iron-responsive element in the 5'-untranslated region of mammalian mitochondrial aconitase

Kim, H.-Y., LaVaute, T., Iwai, K., Klausner, R. D., & Rouault, T. A. (1996) · Journal of Biological Chemistry

Iron Metabolism and DisordersRNA and protein synthesis mechanisms

Cited by 141

Clinical Severity and Thermodynamic Effects of Iron-responsive Element Mutations in Hereditary Hyperferritinemia-Cataract Syndrome

Allerson, C. R., Cazzola, M., & Rouault, T. A. (1999) · Journal of Biological Chemistry

Iron Metabolism and DisordersRNA and protein synthesis mechanisms

Cited by 122

A model for the structure and functions of iron-responsive elements

Hentze, M. W., Caughman, S. W., Casey, J. L., Kodier, D. M., Rouault, T. A., Harford, J. B., & Klausner, R. D. (1988) · Gene

Iron Metabolism and DisordersRNA and protein synthesis mechanisms

Cited by 116

Hepcidin regulates ferroportin expression and intracellular iron homeostasis of erythroblasts

Zhang, D.-L., Senecal, T., Ghosh, M. C., Ollivierre-Wilson, H., Tu, T., & Rouault, T. A. (2011) · Blood

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 113

Ferroportin deficiency in erythroid cells causes serum iron deficiency and promotes hemolysis due to oxidative stress

Zhang, D.-L., Ghosh, M. C., Ollivierre, H., Li, Y., & Rouault, T. A. (2018) · Blood

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 107

Iron control of erythroid development by a novel aconitase-associated regulatory pathway

Bullock, G. C., Delehanty, L. L., Talbot, A.-L., Gonias, S. L., Tong, W.-H., Rouault, T. A., Dewar, B., Macdonald, J. M., Chruma, J. J., & Goldfarb, A. N. (2010) · Blood

Erythropoietin and Anemia TreatmentIron Metabolism and Disorders

Cited by 85

The iron-responsive element is the single element responsible for iron-dependent translational regulation of ferritin biosynthesis: evidence for function as the binding site for a translational repressor.

Caughman, S. W., Hentze, M. W., Rouault, T. A., Harford, J. B., & Klausner, R. D. (1988) · Journal of Biological Chemistry

Iron Metabolism and DisordersRNA and protein synthesis mechanisms

Cited by 85

Pathogenic bacteria prefer heme.

Rouault, T. A. (2004) · Science

Antimicrobial Resistance in StaphylococcusHemoglobin structure and function

Cited by 76

Advancements in the pathophysiology of Friedreich’s Ataxia and new prospects for treatments

Babady, N. E., Carelle, N., Wells, R. D., Rouault, T. A., Hirano, M., Lynch, D. R., Delatycki, M. B., Wilson, R. B., Isaya, G., & Puccio, H. (2007) · Molecular Genetics and Metabolism

Genetic Neurodegenerative DiseasesHereditary Neurological Disorders

Cited by 73

Absence of iron-responsive element-binding protein 2 causes a novel neurodegenerative syndrome.

Costain, G., Ghosh, M. C., Maio, N., Carnevale, A., Si, Y. C., Rouault, T. A., & Yoon, G. (2019) · Brain

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 55