Ghio, Andrew J.

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract

Hou, Y. J., Okuda, K., Edwards, C. E., Martinez, D. R., Asakura, T., Dinnon, K. H., Kato, T., Lee, R. E., Yount, B. L., Mascenik, T. M., et al. (2020) · Cell

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 1,488

Cytokine Production by Human Airway Epithelial Cells after Exposure to an Air Pollution Particle Is Metal-Dependent

Carter, J. D., Ghio, A. J., Samet, J. M., & Devlin, R. B. (1997) · Toxicology and Applied Pharmacology

Air Quality and Health ImpactsHeavy Metal Exposure and Toxicity

Cited by 449

Regulation of reticuloendothelial iron transporter MTP1 (Slc11a3) by inflammation

Yang, F., Liu, X.-B., Quinones, M., Melby, P. C., Ghio, A., & Haile, D. J. (2002) · Journal of Biological Chemistry

Iron Metabolism and DisordersTrace Elements in Health

Cited by 197

Hepcidin expression and iron transport in alveolar macrophages

Nguyen, N.-B., Callaghan, K. D., Ghio, A. J., Haile, D. J., & Yang, F. (2006) · American Journal of Physiology-Lung Cellular and Molecular Physiology

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 143

Role of surface complexed iron in oxidant generation and lung inflammation induced by silicates

Ghio, A. J., Kennedy, T. P., Whorton, A. R., Crumbliss, A. L., Hatch, G. E., & Hoidal, J. R. (1992) · American Journal of Physiology-Lung Cellular and Molecular Physiology

Occupational and environmental lung diseasesInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 132

Metformin targets mitochondrial electron transport to reduce air-pollution-induced thrombosis

Soberanes, S., Misharin, A. V., Jairaman, A., Morales-Nebreda, L., McQuattie-Pimentel, A. C., Cho, T., Hamanaka, R. B., Meliton, A. Y., Reyfman, P. A., Walter, J. M., et al. (2019) · Cell Metabolism

Air Quality and Health ImpactsMetabolism, Diabetes, and Cancer

Cited by 131

Iron and iron-related proteins in the lower respiratory tract of patients with acute respiratory distress syndrome

Ghio, A. J., Carter, J. D., Richards, J. H., Richer, L. D., Grissom, C. K., & Elstad, M. R. (2003) · Critical Care Medicine

Iron Metabolism and DisordersRespiratory Support and Mechanisms

Cited by 105

Review: Ferruginous Bodies: Implications in the Mechanism of Fiber and Particle Toxicity

Ghio, A. J., Churg, A., & Roggli, V. L. (2004) · Toxicologic Pathology

Occupational and environmental lung diseasesInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 89

Iron uptake and Nramp2/DMT1/DCT1 in human bronchial epithelial cells

Wang, X., Ghio, A. J., Yang, F., Dolan, K. G., Garrick, M. D., & Piantadosi, C. A. (2002) · American Journal of Physiology-Lung Cellular and Molecular Physiology

Iron Metabolism and DisordersTrace Elements in Health

Cited by 74

Hydroxyl Radicals are Formed in the Rat Lung After Asbestos Instillation In Vivo

Schapira, R. M., Ghio, A. J., Effros, R. M., Morrisey, J., Dawson, C. A., & Hacker, A. D. (1994) · American Journal of Respiratory Cell and Molecular Biology

Occupational and environmental lung diseasesInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 68

Iron Homeostasis in the Lung Following Asbestos Exposure

Ghio, A. J., Stonehuerner, J., Richards, J., & Devlin, R. B. (2008) · Antioxidants & Redox Signaling

Occupational and environmental lung diseasesIron Metabolism and Disorders

Cited by 65

Hepcidin expression in human airway epithelial cells is regulated by interferon-γ

Frazier, M. D., Mamo, L. B., Ghio, A. J., & Turi, J. L. (2011) · Respiratory Research

Iron Metabolism and DisordersCytokine Signaling Pathways and Interactions

Cited by 64

Cellular and Biochemical Response of the Human Lung after Intrapulmonary Instillation of Ferric Oxide Particles

Lay, J. C., Bennett, W. D., Ghio, A. J., Bromberg, P. A., Costa, D. L., Kim, C. S., Koren, H. S., & Devlin, R. B. (1999) · American Journal of Respiratory Cell and Molecular Biology

Air Quality and Health ImpactsOccupational and environmental lung diseases

Cited by 59

The association between serum ferritin and uric acid in humans

Ghio, A. J., Ford, E. S., Kennedy, T. P., & Hoidal, J. R. (2005) · Free Radical Research

Gout, Hyperuricemia, Uric AcidIron Metabolism and Disorders

Cited by 57

Hypothesis: Is lung disease after silicate inhalation caused by oxidant generation?

Ghio, A. J., Kennedy, T. P., Schapira, R. M., Crumbliss, A. L., & Hoidal, J. R. (1990) · The Lancet

Occupational and environmental lung diseasesInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 56

Apical location of ferroportin 1 in airway epithelia and its role in iron detoxification in the lung

Yang, F., Haile, D. J., Wang, X., Dailey, L. A., Stonehuerner, J. G., & Ghio, A. J. (2005) · American Journal of Physiology-Lung Cellular and Molecular Physiology

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 47

Wood Smoke Particle Sequesters Cell Iron to Impact a Biological Effect

Ghio, A. J., Soukup, J. M., Dailey, L. A., Tong, H., Kesic, M. J., Budinger, G. R. S., & Mutlu, G. M. (2015) · Chemical Research in Toxicology

Air Quality and Health ImpactsHeavy Metal Exposure and Toxicity

Cited by 41

Air pollutants disrupt iron homeostasis to impact oxidant generation, biological effects, and tissue injury

Ghio, A. J., Soukup, J. M., Dailey, L. A., & Madden, M. C. (2020) · Free Radical Biology and Medicine

Iron Metabolism and DisordersHeavy Metal Exposure and Toxicity

Cited by 39

Sequestration of mitochondrial iron by silica particle initiates a biological effect

Ghio, A. J., Tong, H., Soukup, J. M., Dailey, L. A., Cheng, W.-Y., Samet, J. M., Kesic, M. J., Bromberg, P. A., Turi, J. L., Upadhyay, D., et al. (2013) · American Journal of Physiology-Lung Cellular and Molecular Physiology

Occupational and environmental lung diseasesIron Metabolism and Disorders

Cited by 37

Complexation of Iron Cation by Sodium Urate Crystals and Gouty Inflammation

Ghio, A. J., Kennedy, T. P., Rao, G., Cooke, C. L., Miller, M. J., & Hoidal, J. R. (1994) · Archives of Biochemistry and Biophysics

Gout, Hyperuricemia, Uric AcidNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 34

DNA strand breaks following in vitro exposure to asbestos increase with surface-complexed [Fe3+]

Ghio, A. J., Kennedy, T. P., Stonehuerner, J. G., Crumbliss, A. L., & Hoidal, J. R. (1994) · Archives of Biochemistry and Biophysics

Occupational and environmental lung diseasesCarcinogens and Genotoxicity Assessment

Cited by 33

Article Commentary: Effects of Environmental Pollutants on Cellular Iron Homeostasis and Ultimate Links to Human Disease

Schreinemachers, D. M., & Ghio, A. J. (2016) · Environmental Health Insights

Iron Metabolism and DisordersHeavy Metal Exposure and Toxicity

Cited by 32

Perls’ Prussian Blue Stains of Lung Tissue, Bronchoalveolar Lavage, and Sputum

Ghio, A. J., & Roggli, V. L. (2021) · Journal of Environmental Pathology, Toxicology and Oncology

Occupational and environmental lung diseasesInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 29

Oxidant Generation Promotes Iron Sequestration in BEAS-2B Cells Exposed to Asbestos

Wang, X., Wu, Y., Stonehuerner, J. G., Dailey, L. A., Richards, J. D., Jaspers, I., Piantadosi, C. A., & Ghio, A. J. (2006) · American Journal of Respiratory Cell and Molecular Biology

Occupational and environmental lung diseasesIron Metabolism and Disorders

Cited by 27