Maeda, Shin

Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production

Naugler, W. E., Sakurai, T., Kim, S., Maeda, S., Kim, K., Elsharkawy, A. M., & Karin, M. (2007) · Science

Liver physiology and pathologyImmune cells in cancer

Cited by 1,955

Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases

Kamata, H., Honda, S.-I., Maeda, S., Chang, L., Hirata, H., & Karin, M. (2005) · Cell

Redox biology and oxidative stressCell death mechanisms and regulation

Cited by 1,792

IKK-β links inflammation to obesity-induced insulin resistance

Arkan, M. C., Hevener, A. L., Greten, F. R., Maeda, S., Li, Z.-W., Long, J. M., Wynshaw-Boris, A., Poli, G., Olefsky, J., & Karin, M. (2005) · Nature Medicine

Adipokines, Inflammation, and Metabolic DiseasesNF-κB Signaling Pathways

Cited by 1,773

The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover

Chang, L., Kamata, H., Solinas, G., Luo, J.-L., Maeda, S., Venuprasad, K., Liu, Y.-C., & Karin, M. (2006) · Cell

NF-κB Signaling PathwaysUbiquitin and proteasome pathways

Cited by 706

Hepatocyte Necrosis Induced by Oxidative Stress and IL-1α Release Mediate Carcinogen-Induced Compensatory Proliferation and Liver Tumorigenesis

Sakurai, T., He, G., Matsuzawa, A., Yu, G.-Y., Maeda, S., Hardiman, G., & Karin, M. (2008) · Cancer Cell

Liver physiology and pathologyCell death mechanisms and regulation

Cited by 487

Disruption of the transthyretin gene results in mice with depressed levels of plasma retinol and thyroid hormone

Episkopou, V, Maeda, S., Nishiguchi, S., Shimada, K., Gaitanaris, G. A., Gottesman, M. E., & Robertson, E. J. (1993) · Proceedings of the National Academy of Sciences

Retinoids in leukemia and cellular processesProtein Interaction Studies and Fluorescence Analysis

Cited by 325

IKKβ Is Required for Prevention of Apoptosis Mediated by Cell-Bound but Not by Circulating TNFα

Maeda, S., Chang, L., Li, Z.-W., Luo, J.-L., Leffert, H., & Karin, M. (2003) · Immunity

NF-κB Signaling PathwaysCell death mechanisms and regulation

Cited by 286

Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma

Ijichi, H., Chytil, A., Gorska, A. E., Aakre, M. E., Bierie, B., Tada, M., Mohri, D., Miyabayashi, K., Asaoka, Y., Maeda, S., et al. (2011) · Journal of Clinical Investigation

Pancreatic and Hepatic Oncology ResearchChemokine receptors and signaling

Cited by 256

IκB kinase (IKK)β, but not IKKα, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss

Ruocco, M. G., Maeda, S., Park, J. M., Lawrence, T., Hsu, L.-C., Cao, Y., Schett, G., Wagner, E. F., & Karin, M. (2005) · The Journal of Experimental Medicine

Bone Metabolism and DiseasesNF-κB Signaling Pathways

Cited by 252

IκB kinase-α acts in the epidermis to control skeletal and craniofacial morphogenesis

Sil, A. K., Maeda, S., Sano, Y., Roop, D. R., & Karin, M. (2004) · Nature

Developmental Biology and Gene RegulationNF-κB Signaling Pathways

Cited by 211

The Chemokine CXCL16 and Its Receptor, CXCR6, as Markers and Promoters of Inflammation-Associated Cancers

Darash-Yahana, M., Gillespie, J. W., Hewitt, S. M., Chen, Y.-Y. K., Maeda, S., Stein, I., Singh, S. P., Bedolla, R. B., Peled, A., Troyer, D. A., et al. (2009) · PLoS ONE

Chemokine receptors and signalingInflammatory Biomarkers in Disease Prognosis

Cited by 143

Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase

Nakagawa, H., Hirata, Y., Takeda, K., Hayakawa, Y., Sato, T., Kinoshita, H., Sakamoto, K., Nakata, W., Hikiba, Y., Omata, M., et al. (2011) · Hepatology

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 86