Young, Andrew R. J.

Autophagy mediates the mitotic senescence transition

Young, A. R. J., Narita, M., Ferreira, M., Kirschner, K., Sadaie, M., Darot, J. F. J., Tavaré, S., Arakawa, S., Shimizu, S., Watt, F. M., et al. (2009) · Genes & Development

Autophagy in Disease and TherapyTelomeres, Telomerase, and Senescence

Cited by 1,078

Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes

Young, A. R. J., Chan, E. Y. W., Hu, X. W., Köchl, R., Crawshaw, S. G., High, S., Hailey, D. W., Lippincott-Schwartz, J., & Tooze, S. A. (2006) · Journal of Cell Science

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 815

Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes

Narita, M., Young, A. R. J., Arakawa, S., Samarajiwa, S. A., Nakashima, T., Yoshida, S., Hong, S., Berry, L. S., Reichelt, S., Ferreira, M., et al. (2011) · Science

Autophagy in Disease and TherapyPI3K/AKT/mTOR signaling in cancer

Cited by 594

Inside and out: the activities of senescence in cancer

Pérez-Mancera, P. A., Young, A. R. J., & Narita, M. (2014) · Nature Reviews Cancer

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 462

Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence.

Sadaie, M., Salama, R., Carroll, T., Tomimatsu, K., Chandra, T., Young, A. R. J., Narita, M., Pérez-Mancera, P. A., Bennett, D. C., Chong, H., et al. (2013) · Genes & Development

Nuclear Structure and FunctionTelomeres, Telomerase, and Senescence

Cited by 323

SASP reflects senescence

Young, A. R. J., & Narita, M. (2009) · The EMBO Reports

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 214

Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk

Cassidy, L. D., Young, A. R. J., Young, C. N. J., Soilleux, E. J., Fielder, E., Weigand, B. M., Lagnado, A., Brais, R., Ktistakis, N. T., Wiggins, K. A., et al. (2020) · Nature Communications

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 108

COX2 regulates senescence secretome composition and senescence surveillance through PGE2

Gonçalves, S., Yin, K., Ito, Y., Chan, A., Olan, I., Gough, S., Cassidy, L., Serrao, E., Smith, S., Young, A., et al. (2021) · Cell Reports

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 95

LION LBD: a literature-based discovery system for cancer biology

Pyysalo, S., Baker, S., Ali, I., Haselwimmer, S., Shah, T., Young, A., Guo, Y., Högberg, J., Stenius, U., Narita, M., et al. (2019) · Bioinformatics

Biomedical Text Mining and OntologiesBioinformatics and Genomic Networks

Cited by 65

Cell senescence as both a dynamic and a static phenotype

Young, A. R. J., Narita, M., & Narita, M. (2013) · Methods in Molecular Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 50

A novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo

Cassidy, L. D., Young, A. R., Pérez-Mancera, P. A., Nimmervoll, B., Jaulim, A., Chen, H.-C., McIntyre, D. J. O., Brais, R., Ricketts, T., Pacey, S., et al. (2018) · Autophagy

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 40