Accili, Domenico

Post-acute COVID-19 syndrome

Nalbandian, A., Sehgal, K., Gupta, A., Madhavan, M. V., McGroder, C., Stevens, J. S., Cook, J. R., Nordvig, A. S., Shalev, D., Sehrawat, T. S., et al. (2021) · Nature Medicine

Long-Term Effects of COVID-19COVID-19 Clinical Research Studies

Cited by 4,862

Extrapulmonary manifestations of COVID-19

Gupta, A., Madhavan, M. V., Sehgal, K., Nair, N., Mahajan, S., Sehrawat, T. S., Bikdeli, B., Ahluwalia, N., Ausiello, J. C., Wan, E. Y., et al. (2020) · Nature Medicine

COVID-19 Clinical Research StudiesLong-Term Effects of COVID-19

Cited by 3,185

Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction

Puigserver, P., Rhee, J., Donovan, J., Walkey, C. J., Yoon, J. C., Oriente, F., Kitamura, Y., Altomonte, J., Dong, H., Accili, D., et al. (2003) · Nature

FOXO transcription factor regulationMetabolism, Diabetes, and Cancer

Cited by 1,487

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

Talchai, C., Xuan, S., Lin, H. V., Sussel, L., & Accili, D. (2012) · Cell

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 1,415

Biochemical and cellular properties of insulin receptor signalling

Haeusler, R. A., McGraw, T. E., & Accili, D. (2018) · Nature Reviews Molecular Cell Biology

Metabolism, Diabetes, and CancerPancreatic function and diabetes

Cited by 739

Structure-based prediction of protein–protein interactions on a genome-wide scale

Zhang, Q. C., Petrey, D., Deng, L., Qiang, L., Shi, Y., Thu, C. A., Bisikirska, B., Lefebvre, C., Accili, D., Hunter, T., et al. (2012) · Nature

Bioinformatics and Genomic NetworksProtein Structure and Dynamics

Cited by 723

The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

Nakae, J., Kitamura, T., Silver, D. L., & Accili, D. (2001) · Journal of Clinical Investigation

FOXO transcription factor regulationMetabolism, Diabetes, and Cancer

Cited by 652

Insulin/Foxo1 Pathway Regulates Expression Levels of Adiponectin Receptors and Adiponectin Sensitivity

Tsuchida, A., Yamauchi, T., Ito, Y., Hada, Y., Maki, T., Takekawa, S., Kamon, J., Kobayashi, M., Suzuki, R., Hara, K., et al. (2004) · Journal of Biological Chemistry

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 550

Human Insulin Resistance Is Associated With Increased Plasma Levels of 12α-Hydroxylated Bile Acids

Haeusler, R. A., Astiarraga, B., Camastra, S., Accili, D., & Ferrannini, E. (2013) · Diabetes

Drug Transport and Resistance MechanismsCholesterol and Lipid Metabolism

Cited by 444

Hormonal regulation of hepatic glucose production in health and disease

Lin, H. V., & Accili, D. (2011) · Cell Metabolism

Pancreatic function and diabetesMetabolism, Diabetes, and Cancer

Cited by 429

Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance

Hurley, D. M., Accili, D., Stratakis, C. A., Karl, M., Vamvakopoulos, N., Rorer, E., Constantine, K., Taylor, S. I., & Chrousos, G. P. (1991) · Journal of Clinical Investigation

Adrenal Hormones and DisordersEstrogen and related hormone effects

Cited by 370

Mutations in the Insulin Receptor Gene

TAYLOR, S. I., CAMA, A., ACCILI, D., BARBETTI, F., QUON, M. J., SIERRA, M. D. L. L., SUZUKI, Y., ROLLER, E., LEVY-TOLEDANO, R., WERTHEIMER, E., et al. (1992) · Endocrine Reviews

Metabolism, Diabetes, and CancerPancreatic function and diabetes

Cited by 311

Insulin Resistance or Insulin Deficiency: Which Is the Primary Cause of NIDDM?

Taylor, S. I., Accili, D., & Imai, Y. (1994) · Diabetes

Diabetes, Cardiovascular Risks, and LipoproteinsPancreatic function and diabetes

Cited by 289

A Foxo/Notch pathway controls myogenic differentiation and fiber type specification

Kitamura, T., Kitamura, Y. I., Funahashi, Y., Shawber, C. J., Castrillon, D. H., Kollipara, R., DePinho, R. A., Kitajewski, J., & Accili, D. (2007) · Journal of Clinical Investigation

Muscle Physiology and DisordersFOXO transcription factor regulation

Cited by 285

Familial glucocorticoid resistance caused by a splice site deletion in the human glucocorticoid receptor gene

Karl, M., Lamberts, S. W., Detera-Wadleigh, S. D., Encio, I. J., Stratakis, C. A., Hurley, D. M., Accili, D., & Chrousos, G. P. (1993) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersEstrogen and related hormone effects

Cited by 241

How Does Type 1 Diabetes Develop?

Atkinson, M. A., Bluestone, J. A., Eisenbarth, G. S., Hebrok, M., Herold, K. C., Accili, D., Pietropaolo, M., Arvan, P. R., Von Herrath, M., Markel, D. S., et al. (2011) · Diabetes

Diabetes and associated disordersPancreatic function and diabetes

Cited by 232

Reduced expression of the murine p85α subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes

Mauvais-Jarvis, F., Ueki, K., Fruman, D. A., Hirshman, M. F., Sakamoto, K., Goodyear, L. J., Iannacone, M., Accili, D., Cantley, L. C., & Kahn, C. R. (2002) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 207

Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic β-cell mass

Buteau, J., Spatz, M. L., & Accili, D. (2006) · Diabetes

Pancreatic function and diabetesFOXO transcription factor regulation

Cited by 178

Transgenic rescue of insulin receptor–deficient mice

Okamoto, H., Nakae, J., Kitamura, T., Park, B.-C., Dragatsis, I., & Accili, D. (2004) · Journal of Clinical Investigation

Pancreatic function and diabetesMetabolism, Diabetes, and Cancer

Cited by 151

Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Endothelial Cells Accelerates Atherosclerosis in Mice

Westerterp, M., Tsuchiya, K., Tattersall, I. W., Fotakis, P., Bochem, A. E., Molusky, M. M., Ntonga, V., Abramowicz, S., Parks, J. S., Welch, C. L., et al. (2016) · Arteriosclerosis, Thrombosis, and Vascular Biology

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 114

Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay

Fiorentino, L., Cavalera, M., Menini, S., Marchetti, V., Mavilio, M., Fabrizi, M., Conserva, F., Casagrande, V., Menghini, R., Pontrelli, P., et al. (2013) · EMBO Molecular Medicine

Chronic Kidney Disease and DiabetesRenal Diseases and Glomerulopathies

Cited by 98

Tuning insulin receptor signaling using de novo-designed agonists

Wang, X., Cardoso, S., Cai, K., Venkatesh, P., Hung, A., Ng, M., Hall, C., Coventry, B., Lee, D. S., Chowhan, R., et al. (2025) · Molecular Cell

Metabolism, Diabetes, and CancerProtein Structure and Dynamics

Cited by 24

Tuning Insulin Receptor Signaling Using De Novo Designed Agonists

Wang, X., Cardoso, S., Cai, K., Venkatesh, P., Hung, A., Ng, M., Hall, C., Coventry, B., Lee, D., Chowhan, R., et al. (2024) · Molecular Cell

Metabolism, Diabetes, and CancerProtein Structure and Dynamics

Cited by 24