Bennett, Keiryn L.

The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

Mellacheruvu, D., Wright, Z., Couzens, A. L., Lambert, J.-P., St-Denis, N. A., Li, T., Miteva, Y. V., Hauri, S., Sardiu, M. E., Low, T. Y., et al. (2013) · Nature Methods

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 1,686

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

Bürckstümmer, T., Baumann, C., Blüml, S., Dixit, E., Dürnberger, G., Jahn, H., Planyavsky, M., Bilban, M., Colinge, J., Bennett, K. L., et al. (2009) · Nature Immunology

Inflammasome and immune disordersinterferon and immune responses

Cited by 1,091

Gene essentiality and synthetic lethality in haploid human cells

Blomen, V. A., Májek, P., Jae, L. T., Bigenzahn, J. W., Nieuwenhuis, J., Staring, J., Sacco, R., van Diemen, F. R., Olk, N., Stukalov, A., et al. (2015) · Science

Fungal and yeast genetics researchBioinformatics and Genomic Networks

Cited by 857

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

Rebsamen, M., Pochini, L., Stasyk, T., de Araújo, M. E. G., Galluccio, M., Kandasamy, R. K., Snijder, B., Fauster, A., Rudashevskaya, E. L., Bruckner, M., et al. (2015) · Nature

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

Cited by 673

Complement factor H binds malondialdehyde epitopes and protects from oxidative stress

Weismann, D., Hartvigsen, K., Lauer, N., Bennett, K. L., Scholl, H. P. N., Issa, P. C., Cano, M., Brandstätter, H., Tsimikas, S., Skerka, C., et al. (2011) · Nature

Complement system in diseasesRetinal Diseases and Treatments

Cited by 533

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

Grebien, F., Vedadi, M., Getlik, M., Giambruno, R., Grover, A., Avellino, R., Skucha, A., Vittori, S., Kuznetsova, E., Smil, D., et al. (2015) · Nature Chemical Biology

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 284

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

Hantschel, O., Rix, U., Schmidt, U., Bürckstümmer, T., Kneidinger, M., Schütze, G., Colinge, J., Bennett, K. L., Ellmeier, W., Valent, P., et al. (2007) · Proceedings of the National Academy of Sciences

Chronic Myeloid Leukemia TreatmentsMast cells and histamine

Cited by 284

Viral immune modulators perturb the human molecular network by common and unique strategies

Pichlmair, A., Kandasamy, K., Alvisi, G., Mulhern, O., Sacco, R., Habjan, M., Binder, M., Stefanovic, A., Eberle, C.-A., Goncalves, A., et al. (2012) · Nature

interferon and immune responsesImmune Response and Inflammation

Cited by 262

Translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders

Ishoey, M., Chorn, S., Singh, N., Jaeger, M. G., Brand, M., Paulk, J., Bauer, S., Erb, M. A., Parapatics, K., Müller, A. C., et al. (2018) · ACS Chemical Biology

Protein Degradation and InhibitorsChemical Synthesis and Analysis

Cited by 177

Tumor-associated B-cells induce tumor heterogeneity and therapy resistance

Somasundaram, R., Zhang, G., Fukunaga-Kalabis, M., Perego, M., Krepler, C., Xu, X., Wagner, C., Hristova, D., Zhang, J., Tian, T., et al. (2017) · Nature Communications

Melanoma and MAPK PathwaysCancer Immunotherapy and Biomarkers

Cited by 151

Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions

Martins, R., Maier, J., Gorki, A.-D., Huber, K. V. M., Sharif, O., Starkl, P., Saluzzo, S., Quattrone, F., Gawish, R., Lakovits, K., et al. (2016) · Nature Immunology

Sepsis Diagnosis and TreatmentPhagocytosis and Immune Regulation

Cited by 142

Functional Dissection of the TBK1 Molecular Network

Goncalves, A., Bürckstümmer, T., Dixit, E., Scheicher, R., Górna, M. W., Karayel, E., Sugar, C., Stukalov, A., Berg, T., Kralovics, R., et al. (2011) · PLoS ONE

interferon and immune responsesNF-κB Signaling Pathways

Cited by 136

LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning

Filipek, P. A., de Araujo, M. E. G., Vogel, G. F., De Smet, C. H., Eberharter, D., Rebsamen, M., Rudashevskaya, E. L., Kremser, L., Yordanov, T., Tschaikner, P., et al. (2017) · Journal of Cell Biology

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 119

Initial characterization of the human central proteome

Burkard, T. R., Planyavsky, M., Kaupe, I., Breitwieser, F. P., Bürckstümmer, T., Bennett, K. L., Superti-Furga, G., & Colinge, J. (2011) · BMC Systems Biology

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 67