Krishnamurthy, Ramanarayanan
Scripps Research Institute
20 papers on CoChatORCID 0000-0001-5238-610X
Most cited papers
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Chemical Etiology of Nucleic Acid Structure: The α-Threofuranosyl-(3'→2') Oligonucleotide System
Schöning, K.-U., Scholz, P., Guntha, S., Wu, X., Krishnamurthy, R., & Eschenmoser, A. (2000) · Science
DNA and Nucleic Acid ChemistryOrigins and Evolution of Life
Cited by 556
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Ester‐Mediated Amide Bond Formation Driven by Wet–Dry Cycles: A Possible Path to Polypeptides on the Prebiotic Earth
Forsythe, J. G., Yu, S., Mamajanov, I., Grover, M. A., Krishnamurthy, R., Fernández, F. M., & Hud, N. V. (2015) · Angewandte Chemie International Edition
Origins and Evolution of LifeRNA and protein synthesis mechanisms
Cited by 324
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Chemistry of Abiotic Nucleotide Synthesis
Yadav, M., Kumar, R., & Krishnamurthy, R. (2020) · Chemical Reviews
Origins and Evolution of LifeRNA and protein synthesis mechanisms
Cited by 225
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The Origin of RNA and “My Grandfather’s Axe”
Hud, N. V., Cafferty, B. J., Krishnamurthy, R., & Williams, L. D. (2013) · Chemistry & Biology
Origins and Evolution of LifeRNA and protein synthesis mechanisms
Cited by 210
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Linked Cycles of Oxidative Decarboxylation of Glyoxylate as Protometabolic Analogs of the Citric Acid Cycle
Springsteen, G., Yerabolu, J. R., Nelson, J., Rhea, C. J., & Krishnamurthy, R. (2018) · Nature Communications
Origins and Evolution of LifePhysical Organic Chemistry and Reaction Kinetics
Cited by 132
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Selective incorporation of proteinaceous over nonproteinaceous cationic amino acids in model prebiotic oligomerization reactions
Frenkel-Pinter, M., Haynes, J. W., C, M., Petrov, A. S., Burcar, B. T., Krishnamurthy, R., Hud, N. V., Leman, L. J., & Williams, L. D. (2019) · Proceedings of the National Academy of Sciences
Origins and Evolution of LifeRNA and protein synthesis mechanisms
Cited by 128
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Pyranosyl‐RNA (‘p‐RNA’): Base‐pairing selectivity and potential to replicate. Preliminary communication
Pitsch, S., Krishnamurthy, R., Bolli, M., Wendeborn, S., Holzner, A., Minton, M., Lesueur, C., Schlönvogt, I., Jaun, B., & Eschenmoser, A. (1995) · Helvetica Chimica Acta
DNA and Nucleic Acid ChemistryRNA and protein synthesis mechanisms
Cited by 123
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A plausible metal-free ancestral analogue of the Krebs cycle composed entirely of α-ketoacids
Stubbs, R. T., Yadav, M., Krishnamurthy, R., & Springsteen, G. (2020) · Nature Chemistry
Origins and Evolution of LifePhysical Organic Chemistry and Reaction Kinetics
Cited by 117
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Spontaneous Prebiotic Formation of a β-Ribofuranoside That Self-Assembles with a Complementary Heterocycle
Chen, M. C., Cafferty, B. J., Mamajanov, I., Gállego, I., Khanam, J., Krishnamurthy, R., & Hud, N. V. (2014) · Journal of the American Chemical Society
Origins and Evolution of LifeRNA and protein synthesis mechanisms
Cited by 94
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Prebiotic phosphorylation of 2-thiouridine provides either nucleotides or DNA building blocks via photoreduction
Xu, J., Green, N. J., Gibard, C., Krishnamurthy, R., & Sutherland, J. D. (2019) · Nature Chemistry
Origins and Evolution of LifeRNA and protein synthesis mechanisms
Cited by 80
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A Unified Mechanism for Abiotic Adenine and Purine Synthesis in Formamide
Hudson, J. S., Eberle, J. F., Vachhani, R. H., Rogers, L. C., Wade, J. H., Krishnamurthy, R., & Springsteen, G. (2012) · Angewandte Chemie International Edition
Origins and Evolution of LifePhysical Organic Chemistry and Reaction Kinetics
Cited by 80
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Prebiotic synthesis of α-amino acids and orotate from α-ketoacids potentiates transition to extant metabolic pathways
Pulletikurti, S., Yadav, M., Springsteen, G., & Krishnamurthy, R. (2022) · Nature Chemistry
Origins and Evolution of LifeRNA and protein synthesis mechanisms
Cited by 78
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Exploratory Experiments on the Chemistry of the “Glyoxylate Scenario”: Formation of Ketosugars from Dihydroxyfumarate
Sagi, V. N., Punna, V., Hu, F., Meher, G., & Krishnamurthy, R. (2012) · Journal of the American Chemical Society
Origins and Evolution of LifePhysical Organic Chemistry and Reaction Kinetics
Cited by 76
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Life’s Biological Chemistry: A Destiny or Destination Starting from Prebiotic Chemistry?
Krishnamurthy, R. (2018) · Chemistry – A European Journal
Origins and Evolution of LifeSpace Science and Extraterrestrial Life
Cited by 76
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Pentopyranosyl Oligonucleotide Systems. 9th Communication: The β ‐ D ‐Ribopyranosyl‐(4′→2′)‐oligonucleotide System (‘Pyranosyl‐RNA’): Synthesis and Resumé of Base‐Pairing Properties
Pitsch, S., Wendeborn, S., Krishnamurthy, R., Holzner, A., Minton, M., Bolli, M., Miculca, C., Windhab, N., Micura, R., Stanek, M., et al. (2003) · Helvetica Chimica Acta
DNA and Nucleic Acid ChemistryRNA and protein synthesis mechanisms
Cited by 55
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RNA–DNA Chimeras in the Context of an RNA World Transition to an RNA/DNA World
Gavette, J. V., Stoop, M., Hud, N. V., & Krishnamurthy, R. (2016) · Angewandte Chemie International Edition
Origins and Evolution of LifeRNA and protein synthesis mechanisms
Cited by 51
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Cyanide as a primordial reductant enables a protometabolic reductive glyoxylate pathway
Yadav, M., Pulletikurti, S., Yerabolu, J. R., & Krishnamurthy, R. (2022) · Nature Chemistry
Origins and Evolution of LifePhysical Organic Chemistry and Reaction Kinetics
Cited by 48
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Production of Tartrates by Cyanide-Mediated Dimerization of Glyoxylate: A Potential Abiotic Pathway to the Citric Acid Cycle
Butch, C., Cope, E. D., Pollet, P., Gelbaum, L., Krishnamurthy, R., & Liotta, C. L. (2013) · Journal of the American Chemical Society
Origins and Evolution of LifePhysical Organic Chemistry and Reaction Kinetics
Cited by 46
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Cyclophospholipids Enable a Protocellular Life Cycle
Toparlak, Ö. D., Sebastianelli, L., Egas Ortuno, V., Karki, M., Xing, Y., Szostak, J. W., Krishnamurthy, R., & Mansy, S. S. (2023) · ACS Nano
Origins and Evolution of LifeRNA and protein synthesis mechanisms
Cited by 26
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RNA as an emergent entity: an understanding gained through studying its nonfunctional alternatives
Krishnamurthy, R. (2014) · Synlett
RNA and protein synthesis mechanismsOrigins and Evolution of Life
Cited by 17
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