Kuhns, Douglas B.

Residual NADPH Oxidase and Survival in Chronic Granulomatous Disease

Kuhns, D. B., Alvord, W. G., Heller, T., Feld, J. J., Pike, K. M., Marciano, B. E., Uzel, G., DeRavin, S. S., Priel, D. A. L., Soule, B. P., et al. (2010) · New England Journal of Medicine

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmunodeficiency and Autoimmune Disorders

Cited by 568

A Hypermorphic Missense Mutation in PLCG2 , Encoding Phospholipase Cγ2, Causes a Dominantly Inherited Autoinflammatory Disease with Immunodeficiency

Zhou, Q., Lee, G.-S., Brady, J., Datta, S., Katan, M., Sheikh, A., Martins, M. S., Bunney, T. D., Santich, B. H., Moir, S., et al. (2012) · The American Journal of Human Genetics

Immunodeficiency and Autoimmune DisordersInflammasome and immune disorders

Cited by 374

CRISPR-Cas9 gene repair of hematopoietic stem cells from patients with X-linked chronic granulomatous disease

De Ravin, S. S., Li, L., Wu, X., Choi, U., Allen, C., Koontz, S., Lee, J., Theobald-Whiting, N., Chu, J., Garofalo, M., et al. (2017) · Science Translational Medicine

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 258

Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19

Sacco, K., Castagnoli, R., Vakkilainen, S., Liu, C., Delmonte, O. M., Oguz, C., Kaplan, I. M., Alehashemi, S., Burbelo, P. D., Bhuyan, F., et al. (2022) · Nature Medicine

Kawasaki Disease and Coronary ComplicationsCOVID-19 Clinical Research Studies

Cited by 247

HEM1 deficiency disrupts mTORC2 and F-actin control in inherited immunodysregulatory disease

Cook, S. A., Comrie, W. A., Poli, M. C., Similuk, M., Oler, A. J., Faruqi, A. J., Kuhns, D. B., Yang, S., Vargas-Hernández, A., Carisey, A. F., et al. (2020) · Science

Immunodeficiency and Autoimmune DisordersPI3K/AKT/mTOR signaling in cancer

Cited by 102

Genetic immunodeficiency and autoimmune disease reveal distinct roles of Hem1 in the WAVE2 and mTORC2 complexes

Comrie, W. A., Poli, M. C., Cook, S. A., Similuk, M., Oler, A. J., Faruqi, A. J., Kuhns, D. B., Yang, S., Carisey, A. F., Fournier, B., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory)

Immunodeficiency and Autoimmune DisordersT-cell and B-cell Immunology

Cited by 3