Dalkara, Deniz

Adeno-Associated Virus (AAV) - Based Gene Therapies for Retinal Diseases: Where are We?

Ail, D., Malki, H., Zin, E. A., & Dalkara, D. (2023) · The Application of Clinical Genetics

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 40

Outer retinal transduction by AAV2-7m8 following intravitreal injection in a sheep model of CNGA3 achromatopsia

Ross, M., Obolensky, A., Averbukh, E., Desrosiers, M., Ezra-Elia, R., Honig, H., Yamin, E., Rosov, A., Dvir, H., Gootwine, E., et al. (2022) · Gene Therapy

Retinal Development and DisordersVirus-based gene therapy research

Cited by 13

Direct delivery of Cas9 or base editor protein and guide RNA complex enables genome editing in the retina

Pulman, J., Botto, C., Malki, H., Ren, D., Oudin, P., De Cian, A., As, M., Izabelle, C., Saubamea, B., Forster, V., et al. (2024) · Molecular Therapy Nucleic Acids

CRISPR and Genetic EngineeringRetinal Development and Disorders

Cited by 12

268. Optogenetic Engineering of Retinal Ganglion Cells with AAV2.7m8-ChrimsonR-tdTomato (GS030-DP) Is Well Tolerated and Induces Functional Responses to Light in Non-Human Primates

Douar, A. M., Bouquet, C., Pruneau, D., Chavas, J., Dalkara, D., Duebel, J., Benosman, R., Chenegros, G., Picaud, S., Sahel, J., et al. (2016) · Molecular Therapy

Retinal Development and DisordersPhotoreceptor and optogenetics research

Cited by 11

Peripheral cellular immune responses induced by subretinal adeno-associated virus gene transfer can Be restrained by the subretinal-associated immune inhibition mechanism

Vendomèle, J., Chauveau, G. A., Dalkara, D., Galy, A., & Fisson, S. (2024) · Human Gene Therapy

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 6

Characterization of anti-AAV2 neutralizing antibody levels in sheep prior to and following intravitreal AAV2.7m8 injection

Ross, M., Sade, K., Obolensky, A., Averbukh, E., Desrosiers, M., Rosov, A., Dvir, H., Gootwine, E., Banin, E., Dalkara, D., et al. (2024) · Gene Therapy

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 3