Berkhout, Ben

Selecting the optimal Tet‐On system for doxycycline‐inducible gene expression in transiently transfected and stably transduced mammalian cells

Das, A. T., Zhou, X., Metz, S. W., Vink, M. A., & Berkhout, B. (2016) · Biotechnology Journal

Virus-based gene therapy researchGene Regulatory Network Analysis

Cited by 36

Efficient Human Immunodeficiency Virus Replication Requires a Fine-Tuned Level of Transcription

Marzio, G., Vink, M., Verhoef, K., de Ronde, A., & Berkhout, B. (2002) · Journal of Virology

HIV Research and TreatmentEvolution and Genetic Dynamics

Cited by 35

Autoregulatory lentiviral vectors allow multiple cycles of doxycycline-inducible gene expression in human hematopoietic cells in vivo.

Centlivre, M., Zhou, X., Pouw, S. M., Weijer, K., Kleibeuker, W., Das, A. T., Blom, B., Seppen, J., Berkhout, B., & Legrand, N. (2010) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 30

The HIV-1 integrase-LEDGF allosteric inhibitor MUT-A: resistance profile, impairment of virus maturation and infectivity but without influence on RNA packaging or virus immunoreactivity

Amadori, C., van der Velden, Y. U., Bonnard, D., Orlov, I., van Bel, N., Le Rouzic, E., Miralles, L., Brias, J., Chevreuil, F., Spehner, D., et al. (2017) · Retrovirology

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 22

A Sensitive Cell-Based Assay to Measure the Doxycycline Concentration in Biological Samples

Kleibeuker, W., Zhou, X., Centlivre, M., Legrand, N., Page, M., Almond, N., Berkhout, B., & Das, A. T. (2009) · Human Gene Therapy

bioluminescence and chemiluminescence researchAnalytical Methods in Pharmaceuticals

Cited by 20

Conditionally-live attenuated SIV upregulates global T effector memory cell frequency under replication permissive conditions

Manoussaka, M. S., Berry, N., Ferguson, D., Stebbings, R., Robinson, M., Ham, C., Page, M., Li, B., Das, A. T., Berkhout, B., et al. (2013) · Retrovirology

HIV Research and TreatmentT-cell and B-cell Immunology

Cited by 16

Depletion of CD4 T lymphocytes in human lymphoid tissue infected ex vivo with doxycycline-dependent HIV-1

Kiselyeva, Y., Ito, Y., Lima, R. G., Grivel, J.-C., Das, A. T., Berkhout, B., & Margolis, L. B. (2004) · Virology

HIV Research and TreatmentT-cell and Retrovirus Studies

Cited by 13

A doxycycline-dependent human immunodeficiency virus type 1 replicates in vivo without inducing CD4+ T-cell depletion

Legrand, N., van der Velden, G. J., Fang, R. H. T., Douaisi, M., Weijer, K., Das, A. T., Blom, B., Uittenbogaart, C. H., Berkhout, B., & Centlivre, M. (2012) · Journal of General Virology

HIV Research and TreatmentVirus-based gene therapy research

Cited by 8

Construction of Nef-positive doxycycline-dependent HIV-1 variants using bicistronic expression elements

van der Velden, Y. U., Kleibeuker, W., Harwig, A., Klaver, B., Siteur-van Rijnstra, E., Frankin, E., Berkhout, B., & Das, A. T. (2016) · Virology

HIV Research and TreatmentVirus-based gene therapy research

Cited by 3