Sawasaki, Tatsuya

Thalidomide and its metabolite 5‐hydroxythalidomide induce teratogenicity via the cereblon neosubstrate PLZF

Yamanaka, S., Murai, H., Saito, D., Abe, G., Tokunaga, E., Iwasaki, T., Takahashi, H., Takeda, H., Suzuki, T., Shibata, N., et al. (2021) · The EMBO Journal

Protein Degradation and InhibitorsPharmacological Effects and Toxicity Studies

Cited by 89

Structural bases of IMiD selectivity that emerges by 5-hydroxythalidomide

Furihata, H., Yamanaka, S., Honda, T., Miyauchi, Y., Asano, A., Shibata, N., Tanokura, M., Sawasaki, T., & Miyakawa, T. (2020) · Nature Communications

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 89

Lenalidomide derivatives and proteolysis-targeting chimeras for controlling neosubstrate degradation

Yamanaka, S., Furihata, H., Yanagihara, Y., Taya, A., Nagasaka, T., Usui, M., Nagaoka, K., Shoya, Y., Nishino, K., Yoshida, S., et al. (2023) · Nature Communications

Protein Degradation and InhibitorsMultiple Myeloma Research and Treatments

Cited by 73

An IMiD-induced SALL4 degron system for selective degradation of target proteins

Yamanaka, S., Shoya, Y., Matsuoka, S., Nishida-Fukuda, H., Shibata, N., & Sawasaki, T. (2020) · Communications Biology

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 29

Proximity extracellular protein-protein interaction analysis of EGFR using AirID-conjugated fragment of antigen binding

Yamada, K., Shioya, R., Nishino, K., Furihata, H., Hijikata, A., Kaneko, M. K., Kato, Y., Shirai, T., Kosako, H., & Sawasaki, T. (2023) · Nature Communications

Biotin and Related StudiesHER2/EGFR in Cancer Research

Cited by 18

DNA-binding profiling of human hormone nuclear receptors via fluorescence correlation spectroscopy in a cell-free system

Kobayashi, T., Kodani, Y., Nozawa, A., Endo, Y., & Sawasaki, T. (2008) · FEBS Letters

Estrogen and related hormone effectsProtein Interaction Studies and Fluorescence Analysis

Cited by 14