Ting, Jenny P.-Y.

The NLRP3 inflammasome: molecular activation and regulation to therapeutics

Swanson, K. V., Deng, M., & Ting, J. P.-Y. (2019) · Nature Reviews Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 4,884

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

Davis, B. K., Wen, H., & Ting, J. P.-Y. (2011) · Annual Review of Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 1,618

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

Allen, I. C., Scull, M. A., Moore, C. B., Holl, E. K., McElvania-TeKippe, E., Taxman, D. J., Guthrie, E. H., Pickles, R. J., & Ting, J. P.-Y. (2009) · Immunity

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 1,113

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

Allen, I. C., TeKippe, E. M., Woodford, R.-M. T., Uronis, J. M., Holl, E. K., Rogers, A. B., Herfarth, H. H., Jobin, C., & Ting, J. P.-Y. (2010) · Journal of Experimental Medicine

Inflammasome and immune disordersInflammatory Bowel Disease

Cited by 826

Autophagy Links Inflammasomes to Atherosclerotic Progression

Razani, B., Feng, C., Coleman, T., Emanuel, R., Wen, H., Hwang, S., Ting, J. P., Virgin, H. W., Kastan, M. B., & Semenkovich, C. F. (2012) · Cell Metabolism

Atherosclerosis and Cardiovascular DiseasesAutophagy in Disease and Therapy

Cited by 601

A 360° view of the inflammasome: Mechanisms of activation, cell death, and diseases

Barnett, K. C., Li, S., Liang, K., & Ting, J. P.-Y. (2023) · Cell

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 458

NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses

Gris, D., Ye, Z., Iocca, H. A., Wen, H., Craven, R. R., Gris, P., Huang, M., Schneider, M., Miller, S. D., & Ting, J. P.-Y. (2010) · The Journal of Immunology

Inflammasome and immune disordersMultiple Sclerosis Research Studies

Cited by 429

NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes

Freeman, L., Guo, H., David, C. N., Brickey, W. J., Jha, S., & Ting, J. P.-Y. (2017) · Journal of Experimental Medicine

Inflammasome and immune disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 397

NLRs at the intersection of cell death and immunity

Ting, J. P.-Y., Willingham, S. B., & Bergstralh, D. T. (2008) · Nature Reviews Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 371

The Inflammasome Sensor, NLRP3, Regulates CNS Inflammation and Demyelination via Caspase-1 and Interleukin-18

Jha, S., Srivastava, S. Y., Brickey, W. J., Iocca, H., Toews, A., Morrison, J. P., Chen, V. S., Gris, D., Matsushima, G. K., & Ting, J. P.-Y. (2010) · The Journal of Neuroscience

Inflammasome and immune disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 310

The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation

Rodgers, M. A., Bowman, J. W., Fujita, H., Orazio, N., Shi, M., Liang, Q., Amatya, R., Kelly, T. J., Iwai, K., Ting, J., et al. (2014) · Journal of Experimental Medicine

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 247

Induction of MHC Class I Expression by the MHC Class II Transactivator CIITA

Martin, B. K., Chin, K.-C., Olsen, J. C., Skinner, C. A., Dey, A., Ozato, K., & Ting, J. P.-Y. (1997) · Immunity

Genomics and Chromatin DynamicsImmunotherapy and Immune Responses

Cited by 208

The Inflammasome Component Nlrp3 Impairs Antitumor Vaccine by Enhancing the Accumulation of Tumor-Associated Myeloid-Derived Suppressor Cells

van Deventer, H. W., Burgents, J. E., Wu, Q. P., Woodford, R.-M. T., Brickey, W. J., Allen, I. C., McElvania-Tekippe, E., Serody, J. S., & Ting, J. P.-Y. (2010) · Cancer Research

Immunotherapy and Immune ResponsesInflammasome and immune disorders

Cited by 172

Double-stranded RNA innate immune response activation from long-term adeno-associated virus vector transduction

Shao, W., Earley, L. F., Chai, Z., Chen, X., Sun, J., He, T., Deng, M., Hirsch, M. L., Ting, J., Samulski, R. J., et al. (2018) · JCI Insight

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 119

The SecA2 Secretion Factor of Mycobacterium tuberculosis Promotes Growth in Macrophages and Inhibits the Host Immune Response

Kurtz, S., McKinnon, K. P., Runge, M. S., Ting, J. P.-Y., & Braunstein, M. (2006) · Infection and Immunity

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 114

MHC class II exacerbates demyelination in vivo independently of T cells

Hiremath, M. M., Chen, V. S., Suzuki, K., Ting, J. P.-Y., & Matsushima, G. K. (2008) · Journal of Neuroimmunology

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 77

The protective role of nitric oxide in a neurotoxicant-induced demyelinating model

Arnett, H. A., Hellendall, R. P., Matsushima, G. K., Suzuki, K., Laubach, V. E., Sherman, P., & Ting, J. P.-Y. (2002) · The Journal of Immunology

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 71

The 19S proteasome ATPase Sug1 plays a critical role in regulating MHC class II transcription

Bhat, K. P., Turner, J. D., Myers, S. E., Cape, A. D., Ting, J. P.-Y., & Greer, S. F. (2008) · Molecular Immunology

Genomics and Chromatin DynamicsUbiquitin and proteasome pathways

Cited by 53

Lymphotoxin β Receptor (LtβR): Dual Roles in Demyelination and Remyelination and Successful Therapeutic Intervention Using LtβR–Ig Protein

Plant, S. R., Iocca, H. A., Wang, Y., Thrash, J. C., O'Connor, B. P., Arnett, H. A., Fu, Y.-X., Carson, M. J., & Ting, J. P.-Y. (2007) · The Journal of Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 51