Maechler, Pierre

Mitochondrial function in normal and diabetic β-cells

Maechler, P., & Wollheim, C. B. (2001) · Nature

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 519

Regulation of Insulin Secretion by SIRT4, a Mitochondrial ADP-ribosyltransferase

Ahuja, N., Schwer, B., Carobbio, S., Waltregny, D., North, B. J., Castronovo, V., Maechler, P., & Verdin, E. (2007) · Journal of Biological Chemistry

Sirtuins and Resveratrol in MedicinePancreatic function and diabetes

Cited by 422

Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA

Parone, P. A., Da Cruz, S., Tondera, D., Mattenberger, Y., James, D. I., Maechler, P., Barja, F., & Martinou, J.-C. (2008) · PLoS ONE

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 415

Saturated fatty acid‐induced insulin resistance is associated with mitochondrial dysfunction in skeletal muscle cells

Hirabara, S. M., Curi, R., & Maechler, P. (2010) · Journal of Cellular Physiology

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 215

In beta-cells, mitochondria integrate and generate metabolic signals controlling insulin secretion

Maechler, P., Carobbio, S., & Rubi, B. (2006) · The International Journal of Biochemistry & Cell Biology

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 140

The sensitivity of pancreatic β-cells to mitochondrial injuries triggered by lipotoxicity and oxidative stress.

Li, N., Frigerio, F., & Maechler, P. (2008) · Biochemical Society Transactions

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 114

Diabetes-associated mitochondrial DNA mutation A3243G impairs cellular metabolic pathways necessary for beta cell function

de Andrade, P. B. M., Rubi, B., Frigerio, F., van den Ouweland, J. M. W., Maassen, J. A., & Maechler, P. (2006) · Diabetologia

Mitochondrial Function and PathologyPancreatic function and diabetes

Cited by 98

Loss of Prohibitin Induces Mitochondrial Damages Altering β-Cell Function and Survival and Is Responsible for Gradual Diabetes Development

Supale, S., Thorel, F., Merkwirth, C., Gjinovci, A., Herrera, P. L., Scorrano, L., Meda, P., Langer, T., & Maechler, P. (2013) · Diabetes

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 94

GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution

Karaca, M., Frigerio, F., Migrenne, S., Martin-Levilain, J., Skytt, D. M., Pajecka, K., Martin-del-Rio, R., Gruetter, R., Tamarit-Rodriguez, J., Waagepetersen, H. S., et al. (2015) · Cell Reports

Neuroscience and Neuropharmacology ResearchRegulation of Appetite and Obesity

Cited by 60