Tan, Aik Choon

Patient-derived tumour xenografts as models for oncology drug development

Tentler, J. J., Tan, A. C., Weekes, C. D., Jimeno, A., Leong, S., Pitts, T. M., Arcaroli, J. J., Messersmith, W. A., & Eckhardt, S. G. (2012) · Nature Reviews Clinical Oncology

Cancer Cells and MetastasisCancer Genomics and Diagnostics

Cited by 1,277

Caspase 3–mediated stimulation of tumor cell repopulation during cancer radiotherapy

Huang, Q., Li, F., Liu, X., Li, W., Shi, W., Liu, F.-F., O'Sullivan, B., He, Z., Peng, Y., Tan, A.-C., et al. (2011) · Nature Medicine

Cell death mechanisms and regulationCancer Cells and Metastasis

Cited by 886

Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors

Henry, C. J., Casás-Selves, M., Kim, J., Zaberezhnyy, V., Aghili, L., Daniel, A. E., Jimenez, L., Azam, T., McNamee, E. N., Clambey, E. T., et al. (2015) · Journal of Clinical Investigation

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

Cited by 148

ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53

Sullivan, K. D., Padilla-Just, N., Henry, R. E., Porter, C. C., Kim, J., Tentler, J. J., Eckhardt, S. G., Tan, A. C., DeGregori, J., & Espinosa, J. M. (2012) · Nature Chemical Biology

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 67

Gene Array and Fluorescence In situ Hybridization Biomarkers of Activity of Saracatinib (AZD0530), a Src Inhibitor, in a Preclinical Model of Colorectal Cancer

Arcaroli, J. J., Touban, B. M., Tan, A. C., Varella-Garcia, M., Powell, R. W., Eckhardt, S. G., Elvin, P., Gao, D., & Messersmith, W. A. (2010) · Clinical Cancer Research

Colorectal Cancer Treatments and StudiesCancer Mechanisms and Therapy

Cited by 64

Dual Pharmacological Targeting of the MAP Kinase and PI3K/mTOR Pathway in Preclinical Models of Colorectal Cancer

Pitts, T. M., Newton, T. P., Bradshaw-Pierce, E. L., Addison, R., Arcaroli, J. J., Klauck, P. J., Bagby, S. M., Hyatt, S. L., Purkey, A., Tentler, J. J., et al. (2014) · PLoS ONE

PI3K/AKT/mTOR signaling in cancerColorectal Cancer Treatments and Studies

Cited by 54

PAGER 2.0: an update to the pathway, annotated-list and gene-signature electronic repository for Human Network Biology

Yue, Z., Zheng, Q., Neylon, M. T., Yoo, M., Shin, J., Zhao, Z., Tan, A. C., & Chen, J. Y. (2018) · Nucleic Acids Research

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

Cited by 27