Duncan, Andrew W.

Wnt proteins are lipid-modified and can act as stem cell growth factors

Willert, K., Brown, J. D., Danenberg, E., Duncan, A. W., Weissman, I. L., Reya, T., Yates, J. R., & Nusse, R. (2003) · Nature

Wnt/β-catenin signaling in development and cancerHedgehog Signaling Pathway Studies

Cited by 2,257

A role for Wnt signalling in self-renewal of haematopoietic stem cells

Reya, T., Duncan, A. W., Ailles, L., Domen, J., Scherer, D. C., Willert, K., Hintz, L., Nusse, R., & Weissman, I. L. (2003) · Nature

Hematopoietic Stem Cell TransplantationWnt/β-catenin signaling in development and cancer

Cited by 2,159

The ploidy conveyor of mature hepatocytes as a source of genetic variation

Duncan, A. W., Taylor, M. H., Hickey, R. D., Hanlon Newell, A. E., Lenzi, M. L., Olson, S. B., Finegold, M. J., & Grompe, M. (2010) · Nature

Liver physiology and pathologyMicrotubule and mitosis dynamics

Cited by 525

Frequent Aneuploidy Among Normal Human Hepatocytes

Duncan, A. W., Hanlon Newell, A. E., Smith, L., Wilson, E. M., Olson, S. B., Thayer, M. J., Strom, S. C., & Grompe, M. (2012) · Gastroenterology

Microtubule and mitosis dynamicsLiver physiology and pathology

Cited by 197

The Polyploid State Restricts Hepatocyte Proliferation and Liver Regeneration in Mice

Wilkinson, P. D., Delgado, E. R., Alencastro, F., Leek, M. P., Roy, N., Weirich, M. P., Stahl, E. C., Otero, P. A., Chen, M. I., Brown, W. K., et al. (2019) · Hepatology

Liver physiology and pathologyOrgan Transplantation Techniques and Outcomes

Cited by 135

Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells

Takeishi, K., Collin de l’Hortet, A., Wang, Y., Handa, K., Guzman-Lepe, J., Matsubara, K., Morita, K., Jang, S., Haep, N., Florentino, R. M., et al. (2020) · Cell Reports

Tissue Engineering and Regenerative MedicinePluripotent Stem Cells Research

Cited by 118

MicroRNA‐122 regulates polyploidization in the murine liver

Hsu, S., Delgado, E. R., Otero, P. A., Teng, K., Kutay, H., Meehan, K. M., Moroney, J. B., Monga, J. K., Hand, N. J., Friedman, J. R., et al. (2016) · Hepatology

Liver physiology and pathologyMicroRNA in disease regulation

Cited by 84

Polyploid Hepatocytes Facilitate Adaptation and Regeneration to Chronic Liver Injury

Wilkinson, P. D., Alencastro, F., Delgado, E. R., Leek, M. P., Weirich, M. P., Otero, P. A., Roy, N., Brown, W. K., Oertel, M., & Duncan, A. W. (2019) · The American Journal of Pathology

Liver physiology and pathologyOrgan Transplantation Techniques and Outcomes

Cited by 60

ESRP2–microRNA-122 axis promotes the postnatal onset of liver polyploidization and maturation

Bangru, S., Chen, J., Baker, N., Das, D., Chembazhi, U. V., Derham, J. M., Chorghade, S., Arif, W., Alencastro, F., Duncan, A. W., et al. (2025) · Genes & Development

RNA Research and SplicingLiver physiology and pathology

Cited by 4