Duncan, James S.

Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex

Zawistowski, J. S., Bevill, S. M., Goulet, D. R., Stuhlmiller, T. J., Beltran, A. S., Olivares-Quintero, J. F., Singh, D., Sciaky, N., Parker, J. S., Rashid, N. U., et al. (2017) · Cancer Discovery

Melanoma and MAPK PathwaysChromatin Remodeling and Cancer

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The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells

Kurimchak, A. M., Herrera-Montávez, C., Montserrat-Sangrà, S., Araiza-Olivera, D., Hu, J., Neumann-Domer, R., Kuruvilla, M., Bellacosa, A., Testa, J. R., Jin, J., et al. (2022) · Science Signaling

Protein Degradation and InhibitorsDrug Transport and Resistance Mechanisms

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NetrinG1(+) cancer-associated fibroblasts generate unique extracellular vesicles that support the survival of pancreatic cancer cells under nutritional stress

Raghavan, K. S., Francescone, R., Franco-Barraza, J., Gardiner, J. C., Vendramini-Costa, D. B., Luong, T., Pourmandi, N., Andren, A., Kurimchak, A., Ogier, C., et al. (2022) · Cancer Research Communications

Extracellular vesicles in diseasePancreatic and Hepatic Oncology Research

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Rac1 selectively binds a specific lamellipodin isoform via a noncanonical helical interface

Gao, T., Zhang, P., Kurimchak, A. M., Duncan, J. S., & Wu, J. (2026) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

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Rac1 Selectively Binds a Specific Lamellipodin Isoform via a Noncanonical Helical Interface

Gao, T., Zhang, P., Kurimchak, A. M., Duncan, J. S., & Wu, J. (2025) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

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