Theodoris, Christina V.

Transfer learning enables predictions in network biology

Theodoris, C. V., Xiao, L., Chopra, A., Chaffin, M. D., Al Sayed, Z. R., Hill, M. C., Mantineo, H., Brydon, E. M., Zeng, Z., Liu, X. S., et al. (2023) · Nature

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 1,193

Human Disease Modeling Reveals Integrated Transcriptional and Epigenetic Mechanisms of NOTCH1 Haploinsufficiency

Theodoris, C. V., Li, M., White, M. P., Liu, L., He, D., Pollard, K. S., Bruneau, B. G., & Srivastava, D. (2015) · Cell

Genomics and Chromatin DynamicsCardiac Valve Diseases and Treatments

Cited by 210

Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease

Theodoris, C. V., Zhou, P., Liu, L., Zhang, Y., Nishino, T., Huang, Y., Kostina, A., Ranade, S. S., Gifford, C. A., Uspenskiy, V., et al. (2021) · Science

Computational Drug Discovery MethodsGene Regulatory Network Analysis

Cited by 105

MIRA: joint regulatory modeling of multimodal expression and chromatin accessibility in single cells

Lynch, A. W., Theodoris, C. V., Long, H. W., Brown, M., Liu, X. S., & Meyer, C. A. (2022) · Nature Methods

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 80