Yang, Ming

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

Chowdhury, R., Yeoh, K. K., Tian, Y., Hillringhaus, L., Bagg, E. A., Rose, N. R., Leung, I. K. H., Li, X. S., Woon, E. C. Y., Yang, M., et al. (2011) · The EMBO Reports

Cancer, Hypoxia, and MetabolismEpigenetics and DNA Methylation

Cited by 1,035

Serine and one-carbon metabolism in cancer

Yang, M., & Vousden, K. H. (2016) · Nature Reviews Cancer

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 992

GDF15 mediates the effects of metformin on body weight and energy balance

Coll, A. P., Chen, M., Taskar, P., Rimmington, D., Patel, S., Tadross, J. A., Cimino, I., Yang, M., Welsh, P., Virtue, S., et al. (2020) · Nature

GDF15 and Related BiomarkersRegulation of Appetite and Obesity

Cited by 584

Convergent somatic mutations in metabolism genes in chronic liver disease

Ng, S. W. K., Rouhani, F. J., Brunner, S. F., Brzozowska, N., Aitken, S. J., Yang, M., Abascal, F., Moore, L., Nikitopoulou, E., Chappell, L., et al. (2021) · Nature

Cancer Genomics and DiagnosticsLiver Disease Diagnosis and Treatment

Cited by 190

The emerging role of fumarate as an oncometabolite

Yang, M., Soga, T., Pollard, P. J., & Adam, J. (2012) · Frontiers in Oncology

Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism

Cited by 189

Inhibition of Mitochondrial Aconitase by Succination in Fumarate Hydratase Deficiency

Ternette, N., Yang, M., Laroyia, M., Kitagawa, M., O’Flaherty, L., Wolhulter, K., Igarashi, K., Saito, K., Kato, K., Fischer, R., et al. (2013) · Cell Reports

Cancer, Hypoxia, and MetabolismMitochondrial Function and Pathology

Cited by 158

Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans

Ge, W., Wolf, A., Feng, T., Ho, C.-H., Sekirnik, R., Zayer, A., Granatino, N., Cockman, M. E., Loenarz, C., Loik, N. D., et al. (2012) · Nature Chemical Biology

RNA and protein synthesis mechanismsRNA modifications and cancer

Cited by 154

A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia

Adam, J., Yang, M., Bauerschmidt, C., Kitagawa, M., O’Flaherty, L., Maheswaran, P., Özkan, G., Sahgal, N., Baban, D., Kato, K., et al. (2013) · Cell Reports

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 97