Denk, Winfried

Two-photon laser scanning fluorescence microscopy

Denk, W., Strickler, J. H., & Webb, W. W. (1990) · Science

Advanced Fluorescence Microscopy TechniquesNonlinear Optical Materials Studies

Cited by 9,488

Serial Block-Face Scanning Electron Microscopy to Reconstruct Three-Dimensional Tissue Nanostructure

Denk, W., & Horstmann, H. (2004) · PLoS Biology

Advanced Electron Microscopy Techniques and ApplicationsElectron and X-Ray Spectroscopy Techniques

Cited by 1,644

Connectomic reconstruction of the inner plexiform layer in the mouse retina

Helmstaedter, M., Briggman, K. L., Turaga, S. C., Jain, V., Seung, H. S., & Denk, W. (2013) · Nature

Visual perception and processing mechanismsNeuroscience and Neuropharmacology Research

Cited by 997

Dendritic spines as basic functional units of neuronal integration

Yuste, R., & Denk, W. (1995) · Nature

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 950

Wiring specificity in the direction-selectivity circuit of the retina

Briggman, K. L., Helmstaedter, M., & Denk, W. (2011) · Nature

Visual perception and processing mechanismsNeuroscience and Neuropharmacology Research

Cited by 883

Fluctuations and stimulus-induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex

Kleinfeld, D., Mitra, P. P., Helmchen, F., & Denk, W. (1998) · Proceedings of the National Academy of Sciences

Barrier Structure and Function StudiesBlood properties and coagulation

Cited by 832

Lentivirus-based genetic manipulations of cortical neurons and their optical and electrophysiological monitoring in vivo

Dittgen, T., Nimmerjahn, A., Komai, S., Licznerski, P., Waters, J., Margrie, T. W., Helmchen, F., Denk, W., Brecht, M., & Osten, P. (2004) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchVirus-based gene therapy research

Cited by 485

Direct measurement of coupling between dendritic spines and shafts

Svoboda, K., Tank, D. W., & Denk, W. (1996) · Science

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 472

Space–time wiring specificity supports direction selectivity in the retina

EyeWirers, T., Kim, J. S., Greene, M. J., Zlateski, A., Lee, K., Richardson, M., Turaga, S. C., Purcaro, M., Balkam, M., Robinson, A., et al. (2014) · Nature

Visual perception and processing mechanismsNeuroscience and Neuropharmacology Research

Cited by 450

High-precision automated reconstruction of neurons with flood-filling networks

Januszewski, M., Kornfeld, J., Li, P. H., Pope, A., Blakely, T., Lindsey, L., Maitin-Shepard, J., Tyka, M., Denk, W., & Jain, V. (2018) · Nature Methods

Cell Image Analysis TechniquesAdvanced Electron Microscopy Techniques and Applications

Cited by 380

Convolutional Networks Can Learn to Generate Affinity Graphs for Image Segmentation

Turaga, S. C., Murray, J. F., Jain, V., Roth, F., Helmstaedter, M., Briggman, K., Denk, W., & Seung, H. S. (2010) · Neural Computation

Medical Image Segmentation TechniquesAdvanced Neural Network Applications

Cited by 376

Axons and synaptic boutons are highly dynamic in adult visual cortex

Stettler, D. D., Yamahachi, H., Li, W., Denk, W., & Gilbert, C. D. (2006) · Neuron

Neuroscience and Neuropharmacology ResearchVisual perception and processing mechanisms

Cited by 256

Supervised Learning of Image Restoration with Convolutional Networks

Jain, V., Murray, J. F., Roth, F., Turaga, S., Zhigulin, V., Briggman, K. L., Helmstaedter, M. N., Denk, W., & Seung, H. S. (2007) · 2007 IEEE 11th International Conference on Computer Vision

Image and Signal Denoising MethodsAdvanced Image Processing Techniques

Cited by 217

Rapid axonal sprouting and pruning accompany functional reorganization in primary visual cortex

Yamahachi, H., Marik, S. A., McManus, J. N. J., Denk, W., & Gilbert, C. D. (2009) · Neuron

Visual perception and processing mechanismsNeuroscience and Neuropharmacology Research

Cited by 193

Single-spike detection in vitro and in vivo with a genetic Ca2+ sensor

Wallace, D. J., zum Alten Borgloh, S. M., Astori, S., Yang, Y., Bausen, M., Kügler, S., Palmer, A. E., Tsien, R. Y., Sprengel, R., Kerr, J. N. D., et al. (2008) · Nature Methods

Advanced Fluorescence Microscopy TechniquesNeuroscience and Neuropharmacology Research

Cited by 191

The Mind of a Mouse

Abbott, L. F., Bock, D. D., Callaway, E. M., Denk, W., Dulac, C., Fairhall, A. L., Fiete, I., Harris, K. M., Helmstaedter, M., Jain, V., et al. (2020) · Cell

Functional Brain Connectivity StudiesNeuroscience and Neuropharmacology Research

Cited by 172

Automated synapse-level reconstruction of neural circuits in the larval zebrafish brain

Svara, F., Förster, D., Kubo, F., Januszewski, M., dal Maschio, M., Schubert, P. J., Kornfeld, J., Wanner, A. A., Laurell, E., Denk, W., et al. (2022) · Nature Methods

Advanced Electron Microscopy Techniques and ApplicationsCell Image Analysis Techniques

Cited by 124