Prehn, Cornelia

Human metabolic individuality in biomedical and pharmaceutical research

CARDIoGRAM, Suhre, K., Shin, S.-Y., Petersen, A.-K., Mohney, R. P., Meredith, D., Wägele, B., Altmaier, E., Deloukas, P., Erdmann, J., et al. (2011) · Nature

Genetic Associations and EpidemiologyMetabolomics and Mass Spectrometry Studies

Cited by 1,017

Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach

Floegel, A., Stefan, N., Yu, Z., Mühlenbruch, K., Drogan, D., Joost, H.-G., Fritsche, A., Häring, H.-U., Hrabě de Angelis, M., Peters, A., et al. (2013) · Diabetes

Metabolomics and Mass Spectrometry StudiesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 988

Novel biomarkers for pre-diabetes identified by metabolomics

Wang‐Sattler, R., Yu, Z., Herder, C., Messias, A. C., Floegel, A., He, Y., Heim, K., Campillos, M., Holzapfel, C., Thorand, B., et al. (2012) · Molecular Systems Biology

Metabolomics and Mass Spectrometry StudiesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 701

A genome-wide perspective of genetic variation in human metabolism

Illig, T., Gieger, C., Zhai, G., Römisch-Margl, W., Wang-Sattler, R., Prehn, C., Altmaier, E., Kastenmüller, G., Kato, B. S., Mewes, H.-W., et al. (2010) · Nature Genetics

Genetic Associations and EpidemiologyMetabolomics and Mass Spectrometry Studies

Cited by 653

Rapamycin extends murine lifespan but has limited effects on aging

Neff, F., Flores-Dominguez, D., Ryan, D. P., Horsch, M., Schröder, S., Adler, T., Afonso, L. C., Aguilar-Pimentel, J. A., Becker, L., Garrett, L., et al. (2013) · Journal of Clinical Investigation

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 374

Human serum metabolic profiles are age dependent

Yu, Z., Zhai, G., Singmann, P., He, Y., Xu, T., Prehn, C., Römisch‐Margl, W., Lattka, E., Gieger, C., Soranzo, N., et al. (2012) · Aging Cell

Metabolomics and Mass Spectrometry StudiesGenetics, Aging, and Longevity in Model Organisms

Cited by 340

The dynamic range of the human metabolome revealed by challenges

Krug, S., Kastenmüller, G., Stückler, F., Rist, M. J., Skurk, T., Sailer, M., Raffler, J., Römisch‐Margl, W., Adamski, J., Prehn, C., et al. (2012) · The FASEB Journal

Metabolomics and Mass Spectrometry StudiesHealth, Environment, Cognitive Aging

Cited by 327

Interlaboratory Reproducibility of a Targeted Metabolomics Platform for Analysis of Human Serum and Plasma

Siskos, A. P., Jain, P., Römisch-Margl, W., Bennett, M., Achaintre, D., Asad, Y., Marney, L., Richardson, L., Koulman, A., Griffin, J. L., et al. (2017) · Analytical Chemistry

Metabolomics and Mass Spectrometry StudiesClinical Laboratory Practices and Quality Control

Cited by 269

Discovery of phosphatidylcholines and sphingomyelins as biomarkers for ovarian endometriosis

Vouk, K., Hevir, N., Ribič-Pucelj, M., Haarpaintner, G., Scherb, H., Osredkar, J., Möller, G., Prehn, C., Rižner, T. L., & Adamski, J. (2012) · Human Reproduction

Endometriosis Research and TreatmentMetabolomics and Mass Spectrometry Studies

Cited by 143

Metabolites associate with kidney function decline and incident chronic kidney disease in the general population

Goek, O.-N., Prehn, C., Sekula, P., Römisch-Margl, W., Döring, A., Gieger, C., Heier, M., Koenig, W., Wang-Sattler, R., Illig, T., et al. (2013) · Nephrology Dialysis Transplantation

Metabolomics and Mass Spectrometry StudiesChronic Kidney Disease and Diabetes

Cited by 143

Reliability of serum metabolite concentrations over a 4-month period using a targeted metabolomic approach

Floegel, A., Drogan, D., Wang-Sattler, R., Prehn, C., Illig, T., Adamski, J., Joost, H.-G., Boeing, H., & Pischon, T. (2011) · PLoS ONE

Metabolomics and Mass Spectrometry StudiesClinical Laboratory Practices and Quality Control

Cited by 135

Serum Metabolite Concentrations and Decreased GFR in the General Population

Goek, O.-N., Döring, A., Gieger, C., Heier, M., Koenig, W., Prehn, C., Römisch-Margl, W., Wang-Sattler, R., Illig, T., Suhre, K., et al. (2012) · American Journal of Kidney Diseases

Metabolomics and Mass Spectrometry StudiesChronic Kidney Disease and Diabetes

Cited by 121

Amino acids, lipid metabolites, and ferritin as potential mediators linking red meat consumption to type 2 diabetes

Wittenbecher, C., Mühlenbruch, K., Kröger, J., Jacobs, S., Kuxhaus, O., Floegel, A., Fritsche, A., Pischon, T., Prehn, C., Adamski, J., et al. (2015) · The American Journal of Clinical Nutrition

Nutritional Studies and DietMetabolomics and Mass Spectrometry Studies

Cited by 120

Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models

Allesøe, R. L., Lundgaard, A. T., Hernández Medina, R., Aguayo-Orozco, A., Johansen, J., Nissen, J. N., Brorsson, C., Mazzoni, G., Niu, L., Biel, J. H., et al. (2023) · Nature Biotechnology

Bioinformatics and Genomic NetworksComputational Drug Discovery Methods

Cited by 111

Machine Learning Approaches Reveal Metabolic Signatures of Incident Chronic Kidney Disease in Individuals With Prediabetes and Type 2 Diabetes

Huang, J., Huth, C., Covic, M., Troll, M., Adam, J., Zukunft, S., Prehn, C., Wang, L., Nano, J., Scheerer, M. F., et al. (2020) · Diabetes

Chronic Kidney Disease and DiabetesMetabolomics and Mass Spectrometry Studies

Cited by 60

A single night of sleep curtailment increases plasma acylcarnitines: Novel insights in the relationship between sleep and insulin resistance

van den Berg, R., Mook-Kanamori, D. O., Donga, E., van Dijk, M., van Dijk, J. G., Lammers, G.-J., van Kralingen, K. W., Prehn, C., Adamski, J., Romijn, J. A., et al. (2016) · Archives of Biochemistry and Biophysics

Sleep and Work-Related FatigueSleep and related disorders

Cited by 55

12-Months metabolic changes among gender dysphoric individuals under cross-sex hormone treatment: a targeted metabolomics study

Auer, M. K., Cecil, A., Roepke, Y., Bultynck, C., Pas, C., Fuss, J., Prehn, C., Wang-Sattler, R., Adamski, J., Stalla, G. K., et al. (2016) · Scientific Reports

Metabolomics and Mass Spectrometry StudiesLGBTQ Health, Identity, and Policy

Cited by 54

A novel N‐ethyl‐N‐nitrosourea–induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model

Abe, K., Fuchs, H., Boersma, A., Hans, W., Yu, P., Kalaydjiev, S., Klaften, M., Adler, T., Calzada‐Wack, J., Mossbrugger, I., et al. (2011) · Arthritis & Rheumatism

Rheumatoid Arthritis Research and TherapiesSystemic Lupus Erythematosus Research

Cited by 46

Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-induced diabetic mice

Franko, A., Huypens, P., Neschen, S., Irmler, M., Rozman, J., Rathkolb, B., Neff, F., Prehn, C., Dubois, G., Baumann, M., et al. (2016) · Diabetes

Peroxisome Proliferator-Activated ReceptorsDiabetes Treatment and Management

Cited by 42