Tawfik, Dan S.

The Moderately Efficient Enzyme: Evolutionary and Physicochemical Trends Shaping Enzyme Parameters

Bar-Even, A., Noor, E., Savir, Y., Liebermeister, W., Davidi, D., Tawfik, D. S., & Milo, R. (2011) · Biochemistry

Evolution and Genetic DynamicsEnzyme Catalysis and Immobilization

Cited by 1,050

Enzyme promiscuity: evolutionary and mechanistic aspects

Khersonsky, O., Roodveldt, C., & Tawfik, D. S. (2006) · Current Opinion in Chemical Biology

Evolution and Genetic DynamicsProtein Structure and Dynamics

Cited by 641

Local fitness landscape of the green fluorescent protein

Sarkisyan, K. S., Bolotin, D. A., Meer, M. V., Usmanova, D. R., Mishin, A. S., Sharonov, G. V., Ivankov, D. N., Bozhanova, N. G., Baranov, M. S., Soylemez, O., et al. (2016) · Nature

Evolution and Genetic DynamicsRNA and protein synthesis mechanisms

Cited by 591

Conformational diversity and protein evolution – a 60-year-old hypothesis revisited

James, L. C., & Tawfik, D. S. (2003) · Trends in Biochemical Sciences

Protein Structure and DynamicsEvolution and Genetic Dynamics

Cited by 579

Robustness–epistasis link shapes the fitness landscape of a randomly drifting protein

Bershtein, S., Segal, M., Bekerman, R., Tokuriki, N., & Tawfik, D. S. (2006) · Nature

Evolution and Genetic DynamicsRNA and protein synthesis mechanisms

Cited by 414

Amplification of complex gene libraries by emulsion PCR

Williams, R., Peisajovich, S. G., Miller, O. J., Magdassi, S., Tawfik, D. S., & Griffiths, A. D. (2006) · Nature Methods

Molecular Biology Techniques and ApplicationsGenomics and Phylogenetic Studies

Cited by 358

Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase

Jackson, C. J., Foo, J.-L., Tokuriki, N., Afriat, L., Carr, P. D., Kim, H.-K., Schenk, G., Tawfik, D. S., & Ollis, D. L. (2009) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsPhysical Organic Chemistry and Reaction Kinetics

Cited by 119

Potential role of phenotypic mutations in the evolution of protein expression and stability

Goldsmith, M., & Tawfik, D. S. (2009) · Proceedings of the National Academy of Sciences

Evolution and Genetic DynamicsRNA and protein synthesis mechanisms

Cited by 81