Gasmi, Mehdi

Preclinical evaluation of ADVM-022, a novel gene therapy approach to treating wet age-related macular degeneration

Grishanin, R., Vuillemenot, B., Sharma, P., Keravala, A., Greengard, J., Gelfman, C., Blumenkrantz, M., Lawrence, M., Hu, W., Kiss, S., et al. (2019) · Molecular Therapy

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 127

Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress

Dorrell, M. I., Aguilar, E., Jacobson, R., Yanes, O., Gariano, R., Heckenlively, J., Banin, E., Ramirez, G. A., Gasmi, M., Bird, A., et al. (2009) · Journal of Clinical Investigation

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 127

Transgene Expression, Bioactivity, and Safety of CERE-120 (AAV2-Neurturin) Following Delivery to the Monkey Striatum

Herzog, C. D., Dass, B., Gasmi, M., Bakay, R., Stansell, J. E., Tuszynski, M., Bankiewicz, K., Chen, E.-Y., Chu, Y., Bishop, K., et al. (2008) · Molecular Therapy

Virus-based gene therapy researchParkinson's Disease Mechanisms and Treatments

Cited by 72

Comprehensive preclinical assessment of ADVM-022, an intravitreal anti-VEGF gene therapy for the treatment of neovascular AMD and diabetic macular edema

Gelfman, C. M., Grishanin, R., Bender, K. O., Nguyen, A., Greengard, J., Sharma, P., Nieves, J., Kiss, S., & Gasmi, M. (2021) · Journal of Ocular Pharmacology and Therapeutics

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 55

Long-term safety evaluation of continuous intraocular delivery of aflibercept by the intravitreal gene therapy candidate ADVM-022 in nonhuman primates

Kiss, S., Oresic Bender, K., Grishanin, R. N., Hanna, K. M., Nieves, J. D., Sharma, P., Nguyen, A. T., Rosario, R. J., Greengard, J. S., Gelfman, C. M., et al. (2021) · Translational Vision Science & Technology

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 36

Structure comparison of the chimeric AAV2.7m8 vector with parental AAV2

Bennett, A., Keravala, A., Makal, V., Kurian, J., Belbellaa, B., Aeran, R., Tseng, Y.-S., Sousa, D., Spear, J., Gasmi, M., et al. (2020) · Journal of Structural Biology

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 33

Analysis of Aflibercept Expression in NHPs following Intravitreal Administration of ADVM-022, a Potential Gene Therapy for nAMD

Kiss, S., Grishanin, R., Nguyen, A., Rosario, R., Greengard, J. S., Nieves, J., Gelfman, C. M., & Gasmi, M. (2020) · Molecular Therapy - Methods & Clinical Development

Retinal Diseases and TreatmentsVirus-based gene therapy research

Cited by 29