Barchet, Winfried

Cyclic [G(2′,5′)pA(3′,5′)p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.

Gao, P., Ascano, M., Wu, Y., Barchet, W., Gaffney, B. L., Zillinger, T., Serganov, A. A., Liu, Y., Jones, R. A., Hartmann, G., et al. (2013) · Cell

interferon and immune responsesPhosphodiesterase function and regulation

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Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5

Züst, R., Cervantes-Barragan, L., Habjan, M., Maier, R., Neuman, B. W., Ziebuhr, J., Szretter, K. J., Baker, S. C., Barchet, W., Diamond, M. S., et al. (2011) · Nature Immunology

interferon and immune responsesRNA modifications and cancer

Cited by 811

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

Goubau, D., Schlee, M., Deddouche, S., Pruijssers, A. J., Zillinger, T., Goldeck, M., Schuberth, C., Van der Veen, A. G., Fujimura, T., Rehwinkel, J., et al. (2014) · Nature

interferon and immune responsesImmune Response and Inflammation

Cited by 557

Cd8 + T Cells Orchestrate pDC-XCR1 + Dendritic Cell Spatial and Functional Cooperativity to Optimize Priming

Brewitz, A., Eickhoff, S., Dähling, S., Quast, T., Bedoui, S., Kroczek, R. A., Kurts, C., Garbi, N., Barchet, W., Iannacone, M., et al. (2017) · Immunity

Immunotherapy and Immune ResponsesT-cell and B-cell Immunology

Cited by 339

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

Liehl, P., Zuzarte-Luís, V., Chan, J., Zillinger, T., Baptista, F., Carapau, D., Konert, M., Hanson, K. K., Carret, C., Lassnig, C., et al. (2014) · Nature Medicine

interferon and immune responsesMalaria Research and Control

Cited by 313

ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING

Aden, K., Tran, F., Ito, G., Sheibani-Tezerji, R., Lipinski, S., Kuiper, J. W., Tschurtschenthaler, M., Saveljeva, S., Bhattacharyya, J., Häsler, R., et al. (2018) · Journal of Experimental Medicine

Inflammatory Bowel Diseaseinterferon and immune responses

Cited by 167

Suppressive oligodeoxynucleotides containing TTAGGG motifs inhibit cGAS activation in human monocytes

Steinhagen, F., Zillinger, T., Peukert, K., Fox, M., Thudium, M., Barchet, W., Putensen, C., Klinman, D., Latz, E., & Bode, C. (2018) · European Journal of Immunology

interferon and immune responsesSystemic Lupus Erythematosus Research

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