Goldring, Christopher E.

Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

Bell, C. C., Hendriks, D. F. G., Moro, S. M. L., Ellis, E., Walsh, J., Renblom, A., Fredriksson Puigvert, L., Dankers, A. C. A., Jacobs, F., Snoeys, J., et al. (2016) · Scientific Reports

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

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Physical and functional interaction of sequestosome 1 with Keap1 regulates the Keap1-Nrf2 cell defense pathway

Copple, I. M., Lister, A., Obeng, A. D., Kitteringham, N. R., Jenkins, R. E., Layfield, R., Foster, B. J., Goldring, C. E., & Park, B. K. (2010) · Journal of Biological Chemistry

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

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Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity—Implications for therapeutic targeting of Nrf2

Olayanju, A., Copple, I. M., Bryan, H. K., Edge, G. T., Sison, R. L., Wong, M. W., Lai, Z.-Q., Lin, Z.-X., Dunn, K., Sanderson, C. M., et al. (2015) · Free Radical Biology and Medicine

Genomics, phytochemicals, and oxidative stressBioactive Compounds and Antitumor Agents

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Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation

Lauschke, V. M., Vorrink, S. U., Moro, S. M. L., Rezayee, F., Nordling, Å., Hendriks, D. F. G., Bell, C. C., Sison‐Young, R., Park, B. K., Goldring, C. E., et al. (2016) · Hepatology

Liver physiology and pathologyMicroRNA in disease regulation

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Network Analysis of Primary Hepatocyte Dedifferentiation Using a Shotgun Proteomics Approach

Rowe, C., Goldring, C. E. P., Kitteringham, N. R., Jenkins, R. E., Lane, B. S., Sanderson, C., Elliott, V., Platt, V., Metcalfe, P., & Park, B. K. (2010) · Journal of Proteome Research

Liver physiology and pathologyAdvanced Proteomics Techniques and Applications

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Proteomic profiling of murine biliary-derived hepatic organoids and their capacity for drug disposition, bioactivation and detoxification

Howell, L., Jenkins, R. E., Lynch, S., Duckworth, C., Kevin Park, B., & Goldring, C. (2021) · Archives of Toxicology

Drug-Induced Hepatotoxicity and ProtectionPharmacogenetics and Drug Metabolism

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