Mahoney, Jacob P.

Conformational biosensors reveal GPCR signalling from endosomes

Irannejad, R., Tomshine, J. C., Tomshine, J. R., Chevalier, M., Mahoney, J. P., Steyaert, J., Rasmussen, S. G. F., Sunahara, R. K., El-Samad, H., Huang, B., et al. (2013) · Nature

Receptor Mechanisms and SignalingCellular transport and secretion

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Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist

Masureel, M., Zou, Y., Picard, L.-P., van der Westhuizen, E., Mahoney, J. P., Rodrigues, J. P. G. L. M., Mildorf, T. J., Dror, R. O., Shaw, D. E., Bouvier, M., et al. (2018) · Nature Chemical Biology

Receptor Mechanisms and SignalingNeuroscience and Neuropharmacology Research

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The co-receptor Tetraspanin12 directly captures Norrin to promote ligand-specific β-catenin signaling

Bruguera, E. S., Mahoney, J. P., & Weis, W. I. (2025) · eLife

Wnt/β-catenin signaling in development and cancerCell Adhesion Molecules Research

Cited by 9

The co-receptor Tetraspanin12 directly captures Norrin to promote ligand-specific β-catenin signaling

Bruguera, E. S., Mahoney, J. P., & Weis, W. I. (2025) · eLife

Wnt/β-catenin signaling in development and cancerCell Adhesion Molecules Research

Cited by 2

The co-receptor Tetraspanin12 directly captures Norrin to promote ligand-specific β-catenin signaling

Bruguera, E. S., Mahoney, J. P., & Weis, W. I. (2024) · eLife

Wnt/β-catenin signaling in development and cancerCell Adhesion Molecules Research

Cited by 2