Darton, Thomas C

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

Voysey, M., Clemens, S. A. C., Madhi, S. A., Weckx, L. Y., Folegatti, P. M., Aley, P. K., Angus, B., Baillie, V. L., Barnabas, S. L., Bhorat, Q. E., et al. (2021) · The Lancet

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Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials

Voysey, M., Costa Clemens, S. A., Madhi, S. A., Weckx, L. Y., Folegatti, P. M., Aley, P. K., Angus, B., Baillie, V. L., Barnabas, S. L., Bhorat, Q. E., et al. (2021) · The Lancet

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Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial

Emary, K. R. W., Golubchik, T., Aley, P. K., Ariani, C. V., Angus, B., Bibi, S., Blane, B., Bonsall, D., Cicconi, P., Charlton, S., et al. (2021) · The Lancet

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

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An outpatient, ambulant-design, controlled human infection model using escalating doses of Salmonella Typhi challenge delivered in sodium bicarbonate solution

Waddington, C. S., Darton, T. C., Jones, C., Haworth, K., Peters, A., John, T., Thompson, B. A. V., Kerridge, S. A., Kingsley, R. A., Zhou, L., et al. (2014) · Clinical Infectious Diseases

Salmonella and Campylobacter epidemiologyBacterial Infections and Vaccines

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Design, recruitment, and microbiological considerations in human challenge studies

Darton, T. C., Blohmke, C. J., Moorthy, V. S., Altmann, D. M., Hayden, F. G., Clutterbuck, E. A., Levine, M. M., Hill, A. V. S., & Pollard, A. J. (2015) · The Lancet Infectious Diseases

Ethics in Clinical ResearchBacterial Infections and Vaccines

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Typhoid epidemiology, diagnostics and the human challenge model

Darton, T. C., Blohmke, C. J., & Pollard, A. J. (2014) · Current Opinion in Gastroenterology

Salmonella and Campylobacter epidemiologyBacterial Infections and Vaccines

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Rapidly Escalating Hepcidin and Associated Serum Iron Starvation Are Features of the Acute Response to Typhoid Infection in Humans

Darton, T. C., Blohmke, C. J., Giannoulatou, E., Waddington, C. S., Jones, C., Sturges, P., Webster, C., Drakesmith, H., Pollard, A. J., & Armitage, A. E. (2015) · PLOS Neglected Tropical Diseases

Iron Metabolism and DisordersSalmonella and Campylobacter epidemiology

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Efficacy of ChAdOx1 nCoV-19 (AZD1222) Vaccine Against SARS-CoV-2 VOC 202012/01 (B.1.1.7)

Emary, K. R. W., Golubchik, T., Aley, P. K., Ariani, C. V., Angus, B. J., Bibi, S., Blane, B., Bonsall, D., Cicconi, P., Charlton, S., et al. (2021) · SSRN Electronic Journal

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