Arkinson, Connor

Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site

Rennie, M. L., Arkinson, C., Chaugule, V. K., & Walden, H. (2022) · Science Advances

Ubiquitin and proteasome pathwaysEnzyme Structure and Function

Cited by 40

Structural and Biochemical Insights into the Mechanism of Action of the Clinical USP1 Inhibitor, KSQ-4279

Rennie, M. L., Gundogdu, M., Arkinson, C., Liness, S., Frame, S., & Walden, H. (2024) · Journal of Medicinal Chemistry

Ubiquitin and proteasome pathwaysEnzyme Structure and Function

Cited by 27

Nub1 traps unfolded FAT10 for ubiquitin-independent degradation by the 26S proteasome

Arkinson, C., Dong, K. C., Gee, C. L., Costello, S. M., Marqusee, S., & Martin, A. (2024) · Nature Structural & Molecular Biology

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 21

NUB1 traps unfolded FAT10 for ubiquitin-independent degradation by the 26S proteasome

Arkinson, C., Dong, K. C., Gee, C. L., Costello, S. M., Soe, A. C., Hura, G. L., Marqusee, S., & Martin, A. (2025) · Nature Structural & Molecular Biology

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 21