Dyer, Michael A.

Recurrent Somatic Structural Variations Contribute to Tumorigenesis in Pediatric Osteosarcoma

Chen, X., Bahrami, A., Pappo, A., Easton, J., Dalton, J., Hedlund, E., Ellison, D., Shurtleff, S., Wu, G., Wei, L., et al. (2014) · Cell Reports

Sarcoma Diagnosis and TreatmentCancer Genomics and Diagnostics

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Inactivation of the p53 pathway in retinoblastoma

Laurie, N. A., Donovan, S. L., Shih, C.-S., Zhang, J., Mills, N., Fuller, C., Teunisse, A., Lam, S., Ramos, Y., Mohan, A., et al. (2006) · Nature

Cancer-related Molecular PathwaysOcular Oncology and Treatments

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Orthotopic patient-derived xenografts of paediatric solid tumours

Stewart, E., Federico, S. M., Chen, X., Shelat, A. A., Bradley, C., Gordon, B., Karlstrom, A., Twarog, N. R., Clay, M. R., Bahrami, A., et al. (2017) · Nature

Cancer Genomics and DiagnosticsCancer Cells and Metastasis

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MDMX: from bench to bedside

Marine, J.-C. W., Dyer, M. A., & Jochemsen, A. G. (2007) · Journal of Cell Science

Cancer-related Molecular PathwaysUbiquitin and proteasome pathways

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Identification and Characterization of the First Small Molecule Inhibitor of MDMX

Reed, D., Shen, Y., Shelat, A. A., Arnold, L. A., Ferreira, A. M., Zhu, F., Mills, N., Smithson, D. C., Regni, C. A., Bashford, D., et al. (2010) · Journal of Biological Chemistry

Cancer-related Molecular PathwaysHeat shock proteins research

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Rb regulates proliferation and rod photoreceptor development in the mouse retina

Zhang, J., Gray, J., Wu, L., Leone, G., Rowan, S., Cepko, C. L., Zhu, X., Craft, C. M., & Dyer, M. A. (2004) · Nature Genetics

Retinal Development and DisordersNeurogenesis and neuroplasticity mechanisms

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Differentiated Horizontal Interneurons Clonally Expand to Form Metastatic Retinoblastoma in Mice

Ajioka, I., Martins, R. A. P., Bayazitov, I. T., Donovan, S., Johnson, D. A., Frase, S., Cicero, S. A., Boyd, K., Zakharenko, S. S., & Dyer, M. A. (2007) · Cell

Retinal Development and DisordersOcular Oncology and Treatments

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The search for the retinoblastoma cell of origin

Dyer, M. A., & Bremner, R. (2005) · Nature Reviews Cancer

Ocular Oncology and TreatmentsRetinal Development and Disorders

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Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses

Stewart, E., McEvoy, J., Wang, H., Chen, X., Honnell, V., Ocarz, M., Gordon, B., Dapper, J., Blankenship, K., Yang, Y., et al. (2018) · Cancer Cell

Sarcoma Diagnosis and TreatmentChromatin Remodeling and Cancer

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Analysis of MDM2 and MDM4 Single Nucleotide Polymorphisms, mRNA Splicing and Protein Expression in Retinoblastoma

McEvoy, J., Ulyanov, A., Brennan, R., Wu, G., Pounds, S., Zhang, J., & Dyer, M. A. (2012) · PLoS ONE

Cancer-related Molecular PathwaysOcular Oncology and Treatments

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Whole-body physiologically based pharmacokinetic model for nutlin-3a in mice after intravenous and oral administration

Zhang, F., Tagen, M., Throm, S., Mallari, J., Miller, L., Guy, R. K., Dyer, M. A., Williams, R. T., Roussel, M. F., Nemeth, K., et al. (2011) · Drug Metabolism and Disposition

Pharmaceutical studies and practicesPharmacogenetics and Drug Metabolism

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On the Mechanism of Action of SJ-172550 in Inhibiting the Interaction of MDM4 and p53

Bista, M., Smithson, D., Pecak, A., Salinas, G., Pustelny, K., Min, J., Pirog, A., Finch, K., Zdzalik, M., Waddell, B., et al. (2012) · PLoS ONE

Cancer-related Molecular PathwaysHeat shock proteins research

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Combinatorial screening using orthotopic patient derived xenograft-expanded early phase cultures of osteosarcoma identify novel therapeutic drug combinations

Loh, A. H. P., Stewart, E., Bradley, C. L., Chen, X., Daryani, V., Stewart, C. F., Calabrese, C., Funk, A., Miller, G., Karlstrom, A., et al. (2019) · Cancer Letters

Sarcoma Diagnosis and TreatmentBone Tumor Diagnosis and Treatments

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